Navigation Links
2013 Gastrointestinal Cancers Symposium reveals new advances for GI cancers
Date:1/22/2013

ALEXANDRIA, Va. New research into the treatment and prognosis of gastrointestinal cancers was released today in advance of the tenth annual Gastrointestinal Cancers Symposium being held January 24-26, 2013, at The Moscone West Building in San Francisco, CA.

Five important studies were highlighted today in a live presscast:

  • Postoperative Treatment with S-1 Chemotherapy Reduces Relapses and Extends Survival in Patients with Pancreatic Cancer: Early results from a Phase III clinical trial conducted in Japan show patients who received the chemotherapy drug S-1 after surgery for Stage I-III pancreatic adenocarcinoma had a 44 percent lower risk of dying compared with patients treated with gemcitabine. While S-1 is not yet approved in the United States, it is available in several Asian and European countries.

  • New Molecular Classification System for Colorectal Cancer May Help Guide Treatment Choice for Individual Patients: Researchers identified three distinct colorectal cancer subtypes based on gene expression patterns in patients' tumors. The findings may lead to new molecular tests for determining if a patient needs adjuvant treatment and which treatment might be most beneficial.

  • Surgery Following Imatinib Therapy Substantially Improves Survival for Certain Patients with Gastrointestinal Stromal Tumors (GISTs): A new retrospective study validated the benefit of performing surgery to remove residual tumor lesions after imatinib therapy. Patients who received surgery after imatinib had a 5.5 fold lower risk of dying and a nearly 4-year longer time to disease worsening compared with those who received imatinib alone.

  • Profiling Gene Expression in Circulating Tumor Cells Shows Promise as a New Prognostic Strategy for Patients with Pancreatic Cancer: A study profiling gene expression in cells shed from pancreatic tumors into the bloodstream detected genomic changes associated with response and resistance to different treatments. This new profiling strategy may help predict whether or not a patient would respond to a particular chemotherapy regimen.

  • Second-Line Docetaxel Chemotherapy Improves Survival in Patients with Treatment-Resistant Esophageal or Gastric Cancers: A Phase III study showed that patients with esophageal or stomach cancers whose disease worsened despite first-line chemotherapy live on average 50 percent longer if they received second-line docetaxel than if they receive active symptom control (radiotherapy, steroids, and/or supportive medications). While docetaxel is already being used in this setting, the new study provides definitive evidence of survival benefit with second-line docetaxel.

"Research continues to deliver advances that will improve the lives of patients with gastrointestinal cancers, and we are learning to understand how to use molecular characteristics of tumors to choose and customize therapy for individual patients," said Neal J. Meropol, MD, who moderated the presscast. "At this conference, we will see the results of new studies showing life-extending treatments for some of our deadliest and hardest to treat cancers and new insights on tumor classification and prognosis."

Gastrointestinal cancers include those of the colon/rectum, stomach, pancreas, esophagus, small intestine, anus and other digestive organs. In 2012, it was estimated that nearly 285,000 people in the U.S. were diagnosed with these cancers and more than 142,000 will died from them.


'/>"/>

Contact: Susie Tappouni
susie.tappouni@asco.org
571-483-1355
American Society of Clinical Oncology
Source:Eurekalert

Related medicine news :

1. Antibody therapy prevents gastrointestinal damage following radiation exposure in mice
2. Gastroenterology Societies issue sedation curriculum for gastrointestinal endoscopy
3. Dietary fiber alters gut bacteria, supports gastrointestinal health
4. New analysis of drinking water-related gastrointestinal illness
5. Study Assesses Blood Thinner Use After Gastrointestinal Bleeding
6. Targeting neurotransmitter may help treat gastrointestinal conditions
7. Which Hospital Patients Need Drugs to Prevent Gastrointestinal Bleeding?
8. Potential new treatment for gastrointestinal cancers discovered
9. HPV-Related Head, Neck Cancers on the Rise
10. LSUHSC research finds HPV-related head & neck cancers rising, highest in middle-aged white men
11. Kinase test may yield big gains for drug-resistant cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... ... 2016 , ... ODU, a worldwide leader in designing ... advanced highly customizable contact technology solutions. , ODU Single Contact Technology portfolio includes: ... for a wide range of applications that require customization from industries like emobility, ...
(Date:12/7/2016)... ... December 07, 2016 , ... Augustine ... services to families and business owners in the greater Dallas metropolitan area, is ... Dallas Fallen Officer Foundation. , Established in 2009 by active police professionals in ...
(Date:12/7/2016)... ... 2016 , ... A. Kevin Spann Insurance, a New York-based firm offering insurance ... launching a charity drive to raise funds that will benefit the Marine Corps League. ... and Navy FMF Corpsmen. Working closely with the MCL, the A. Kevin Spann team ...
(Date:12/7/2016)... ... December 07, 2016 , ... The ... its fully redesigned website, which launched October 17, 2016, features comprehensive information regarding ... and easy-to-navigate layout. Visitors and patients can discover the latest clinical dermatology treatments ...
(Date:12/7/2016)... Dallas, TX (PRWEB) , ... December 07, 2016 ... ... service based in Dallas, Texas, is condemning "scam operations" carried out by unethical ... to bring these scam operations to a halt. According to Texas Premier Locksmith, ...
Breaking Medicine News(10 mins):
(Date:12/7/2016)... Dec. 7, 2016 KEY FINDINGS ... benefits such as reducing loss of blood during ... cardiac arrests, rapid recovery after surgeries, and decreasing ... be segmented into convective warming system, surface warming ... turn reduce the stay at hospitals thus, lowering ...
(Date:12/7/2016)... DUBLIN , Dec 7, 2016 Research ... Product, Application and End User - Global Forecast to 2021" report ... , , ... reach USD 2.12 Billion by 2021, growing at a CAGR of 7.3% ... such as the growing prevalence of cancer and rapidly increasing geriatric population ...
(Date:12/7/2016)... , Dec. 7, 2016 DelveInsight,s, ... report provides in depth insights on the ... the Janus Kinase 3 (JAK3) Inhibitors. The ... various stages of development including Discovery, Pre-clinical, ... and Preregistration. Report covers the product clinical ...
Breaking Medicine Technology: