Navigation Links
2013 Gastrointestinal Cancers Symposium reveals new advances for GI cancers
Date:1/22/2013

ALEXANDRIA, Va. New research into the treatment and prognosis of gastrointestinal cancers was released today in advance of the tenth annual Gastrointestinal Cancers Symposium being held January 24-26, 2013, at The Moscone West Building in San Francisco, CA.

Five important studies were highlighted today in a live presscast:

  • Postoperative Treatment with S-1 Chemotherapy Reduces Relapses and Extends Survival in Patients with Pancreatic Cancer: Early results from a Phase III clinical trial conducted in Japan show patients who received the chemotherapy drug S-1 after surgery for Stage I-III pancreatic adenocarcinoma had a 44 percent lower risk of dying compared with patients treated with gemcitabine. While S-1 is not yet approved in the United States, it is available in several Asian and European countries.

  • New Molecular Classification System for Colorectal Cancer May Help Guide Treatment Choice for Individual Patients: Researchers identified three distinct colorectal cancer subtypes based on gene expression patterns in patients' tumors. The findings may lead to new molecular tests for determining if a patient needs adjuvant treatment and which treatment might be most beneficial.

  • Surgery Following Imatinib Therapy Substantially Improves Survival for Certain Patients with Gastrointestinal Stromal Tumors (GISTs): A new retrospective study validated the benefit of performing surgery to remove residual tumor lesions after imatinib therapy. Patients who received surgery after imatinib had a 5.5 fold lower risk of dying and a nearly 4-year longer time to disease worsening compared with those who received imatinib alone.

  • Profiling Gene Expression in Circulating Tumor Cells Shows Promise as a New Prognostic Strategy for Patients with Pancreatic Cancer: A study profiling gene expression in cells shed from pancreatic tumors into the bloodstream detected genomic changes associated with response and resistance to different treatments. This new profiling strategy may help predict whether or not a patient would respond to a particular chemotherapy regimen.

  • Second-Line Docetaxel Chemotherapy Improves Survival in Patients with Treatment-Resistant Esophageal or Gastric Cancers: A Phase III study showed that patients with esophageal or stomach cancers whose disease worsened despite first-line chemotherapy live on average 50 percent longer if they received second-line docetaxel than if they receive active symptom control (radiotherapy, steroids, and/or supportive medications). While docetaxel is already being used in this setting, the new study provides definitive evidence of survival benefit with second-line docetaxel.

"Research continues to deliver advances that will improve the lives of patients with gastrointestinal cancers, and we are learning to understand how to use molecular characteristics of tumors to choose and customize therapy for individual patients," said Neal J. Meropol, MD, who moderated the presscast. "At this conference, we will see the results of new studies showing life-extending treatments for some of our deadliest and hardest to treat cancers and new insights on tumor classification and prognosis."

Gastrointestinal cancers include those of the colon/rectum, stomach, pancreas, esophagus, small intestine, anus and other digestive organs. In 2012, it was estimated that nearly 285,000 people in the U.S. were diagnosed with these cancers and more than 142,000 will died from them.


'/>"/>

Contact: Susie Tappouni
susie.tappouni@asco.org
571-483-1355
American Society of Clinical Oncology
Source:Eurekalert

Related medicine news :

1. Antibody therapy prevents gastrointestinal damage following radiation exposure in mice
2. Gastroenterology Societies issue sedation curriculum for gastrointestinal endoscopy
3. Dietary fiber alters gut bacteria, supports gastrointestinal health
4. New analysis of drinking water-related gastrointestinal illness
5. Study Assesses Blood Thinner Use After Gastrointestinal Bleeding
6. Targeting neurotransmitter may help treat gastrointestinal conditions
7. Which Hospital Patients Need Drugs to Prevent Gastrointestinal Bleeding?
8. Potential new treatment for gastrointestinal cancers discovered
9. HPV-Related Head, Neck Cancers on the Rise
10. LSUHSC research finds HPV-related head & neck cancers rising, highest in middle-aged white men
11. Kinase test may yield big gains for drug-resistant cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs ... College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. ... treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a method ... —Johnson is one of the first doctors to perform the treatment. Orthobiologics are ...
(Date:6/24/2016)... Michigan (PRWEB) , ... June 24, 2016 , ... June ... about the dangers associated with chronic pain and the benefits of holistic treatments, ... individuals who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) is ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Comfort ... the American Cancer Society and the Road To Recovery® program to drive cancer patients ... seniors and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® ... Group (TGIG), has initiated cultivation and processing operations at its production facility, and ... Nevada. , Puradigm is the manufacturer of a complete system of proactive air ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... -- Research and Markets has announced ... Applications, Technologies, Forecasts" report to their offering. ... Smart Skin, Structural Health Monitoring, Composite Smart Structures, ... involves electronic and/or electrical components and circuits that ... such as vehicle bodies or conformally placed upon ...
(Date:6/24/2016)... and SAN CLEMENTE, Calif. , June ... -based mobile pulmonary function testing company, is now able to ... devices developed by ndd Medical Technologies , Inc. ... done in hospital-based labs.  Thanks to ndd,s EasyOne PRO ® , ... , can get any needed testing done in the comfort of ...
(Date:6/24/2016)... 2016   Pulmatrix, Inc ., (NASDAQ: ... drugs, announced today that it was added to the ... its comprehensive set of U.S. and global equity indexes ... important milestone for Pulmatrix," said Chief Executive Officer ... our progress in developing drugs for crucial unmet medical ...
Breaking Medicine Technology: