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2013 Gastrointestinal Cancers Symposium reveals new advances for GI cancers
Date:1/22/2013

ALEXANDRIA, Va. New research into the treatment and prognosis of gastrointestinal cancers was released today in advance of the tenth annual Gastrointestinal Cancers Symposium being held January 24-26, 2013, at The Moscone West Building in San Francisco, CA.

Five important studies were highlighted today in a live presscast:

  • Postoperative Treatment with S-1 Chemotherapy Reduces Relapses and Extends Survival in Patients with Pancreatic Cancer: Early results from a Phase III clinical trial conducted in Japan show patients who received the chemotherapy drug S-1 after surgery for Stage I-III pancreatic adenocarcinoma had a 44 percent lower risk of dying compared with patients treated with gemcitabine. While S-1 is not yet approved in the United States, it is available in several Asian and European countries.

  • New Molecular Classification System for Colorectal Cancer May Help Guide Treatment Choice for Individual Patients: Researchers identified three distinct colorectal cancer subtypes based on gene expression patterns in patients' tumors. The findings may lead to new molecular tests for determining if a patient needs adjuvant treatment and which treatment might be most beneficial.

  • Surgery Following Imatinib Therapy Substantially Improves Survival for Certain Patients with Gastrointestinal Stromal Tumors (GISTs): A new retrospective study validated the benefit of performing surgery to remove residual tumor lesions after imatinib therapy. Patients who received surgery after imatinib had a 5.5 fold lower risk of dying and a nearly 4-year longer time to disease worsening compared with those who received imatinib alone.

  • Profiling Gene Expression in Circulating Tumor Cells Shows Promise as a New Prognostic Strategy for Patients with Pancreatic Cancer: A study profiling gene expression in cells shed from pancreatic tumors into the bloodstream detected genomic changes associated with response and resistance
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Contact: Susie Tappouni
susie.tappouni@asco.org
571-483-1355
American Society of Clinical Oncology
Source:Eurekalert

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