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2011 Louis-Jeantet Prize for Medicine
Date:1/26/2011

better understand how they interact with other cells of the entorhinal cortex and hippocampus also contributing to spatial navigation and memory.

The award ceremony will be held in Geneva (Switzerland) on Thursday, 14 April 2011.

Stefan Jentsch

Stefan Jentsch was born 1955 in Berlin, where he studied and obtained his PhD in 1983. Post-doctoral work then followed at the Massachusetts Institute of Technology (MIT) in Cambridge (USA). On his return to Germany, he was research group leader at the Friedrich- Miescher Laboratory of the Max-Planck Society in Tbingen and then professor at the University of Heidelberg. In 2003, he moved to the Max-Planck Institute of Biochemistry in Martinsried, where he heads the Department of Molecular Cell Biology. He is the second member of his family to be awarded the Louis-Jeantet Prize for Medicine: his brother Thomas Jentsch, Head of Department at the Leibniz-Institute for Molecular Pharmacology (FMP/MDC) in Berlin, already won the prize in 2000.

Stefan Jentsch is a fellow of the German National Academy of Sciences Leopoldina and of the European Molecular Biology Organization (EMBO), as well as honorary professor at Fudan University in Shanghai (China). He has already received several distinctions, in particular the Otto Klung Prize for Chemistry, the Otto Bayer Prize, the Gottfried Wilhelm Leibniz Prize and the Max-Planck Research Award from the Humboldt and Max-Planck Societies.

Ubiquitin and human diseases

Each cell has a large number of proteins at its disposal, which steer all life functions. Each protein takes on special tasks, but these can be altered through protein modifications.

Modification of proteins by ubiquitin usually targets the proteins for degradation. Not only did Stefan Jentsch reveal that ubiquitin also plays a crucial role in genome maintenance and DNA repair, but he also was the first to discover the genes for ubiquitin activation an
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Contact: Prof. Bernard C. Rossier
bernard.rossier@unil.ch
41-216-925-351
European Molecular Biology Organization
Source:Eurekalert

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