Navigation Links
2008 AAAS Newcomb Cleveland Prize recognizes science paper on limb regeneration in newts
Date:2/11/2009

A United Kingdom research team's discovery of a new molecular cue that promotes limb regeneration in newts a finding that could help guide the field of regenerative medicine received the 2008 Newcomb Cleveland Prize of the American Association for the Advancement of Science (AAAS).

The Association's oldest prize, now supported by Affymetrix, the Newcomb Cleveland Prize annually recognizes the author or authors of an outstanding paper published in the Research Articles or Reports sections of the journal Science between June and the following May.

When an amphibian's limb is severed, a variety of cell types revert to their earlier stem cell form and then proliferate at the tip of the stump to form a mass of undifferentiated cells, the "blastema," from which the new limb grows. The formation of the blastema requires signaling molecules from nearby nerves, though this process has been poorly understood.

Five Science authors Anoop Kumar, James W. Godwin, Phillip B. Gates, and Jeremy P. Brockes of University College London, along with A. Acely Garza-Garcia of the U.K.'s National Institute for Medical Research, were recognized for their article, entitled "Molecular Basis for the Nerve Dependence of Limb Regeneration in an Adult Vertebrate." (Reference: Science, 2 November 2007, Vol. 318, no. 5851, pp. 772-777. DOI: 10.1126/science.1147710.)

The researchers reported that the protein nAG helps to stimulate the proliferation of the blastema cells. The protein is secreted by both nervous-system cells called Schwann cells and epidermal cells near the wound, which helps explain why nerves are required for blastema formation. Even when the nerve was severed beneath the stump tip, the authors were able to coax the formation of a blastema by artificially inducing cells to express the protein. The blastema was capable of generating a new limb with normal shape, though the limb wasn't fully functional and lacked norm
'/>"/>

Contact: Molly McElroy
mmcelroy@aaas.org
202-326-6434
American Association for the Advancement of Science
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Cleveland Clinic Launches Ground-Breaking Wellness Program To Reverse Effects of Common Chronic Diseases
2. Cleveland House a Sober living Resort, is Celebrating 7 Year Anniversary
3. Cleveland Clinic and Mubadala Healthcare Name CEO of Cleveland Clinic Abu Dhabi
4. Hip Replacement Patients at Possible Risk, Cleveland Law Firm Adds Zimmer Durom Cup Lawsuit Info on SpangLaw.com
5. U.S. Continues to Lag Behind European Countries in Teen Sexual Health - Cleveland Sex Ed Initiative Takes Promising Science-Based Approach
6. Solos Endoscopy, Inc. Receives Purchase Order from Cleveland Clinic
7. PR Newswire Provides Grant to Ronald McDonald House and Habitat for Humanity in Cleveland
8. LifeBanc Assists Cleveland Clinic in First Near Total Face Transplant in the United States
9. Cleveland Injury Attorneys Among 'The Best Lawyers in America'
10. University Hospitals in Cleveland Selects Solution Suite from Agilysys
11. The American Lung Association of Ohio Encourages Cleveland Residents to See Themselves Among The Many Faces of Influenza
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/18/2015)... Omaha, NE (PRWEB) April 18, 2015 ... leader in healthcare staffing, including physical therapy jobs, ... exhibitor at the South Carolina Physical Therapy Association ... at the Kroc Center in Greenville, SC. ... networking opportunities, and exhibits with products and services. ...
(Date:4/18/2015)... (PRWEB) April 18, 2015 PHOENIX, ARIZONA ... County, along with 11 other secure destruction professionals across ... Destruction Specialists (CSDS). He will now display “CSDS” as ... were offered before the National Association of Information Destruction ... and another Grapevine, Texas. Of the 20 people who ...
(Date:4/17/2015)... (PRWEB) April 18, 2015 Heritage Woods ... begin its Supportive Living Week Celebration on April 20 ... having a healthy mind, body and soul. , The ... McLeansboro, Illinois, serves older adults of all incomes, including ... their independence. , Supportive Living Week is observed every ...
(Date:4/17/2015)... Rosetta Radiology is proud to now offer ... of diagnostic imaging services. This solidifies them as a ... East Side of Manhattan. , The new imaging equipment ... of PET-CT, combined with Rosetta’s state of the art ... with patients through several stages of the cancer care ...
(Date:4/17/2015)... (PRWEB) April 17, 2015 Riviera ... Dr. Kevin Sadati of the Gallery of Cosmetic ... County’s top beauty experts. The publication focused on ... facial stem cell fat grafting, eyelid surgery, laser resurfacing ... facial plastic surgery has resulted in thousands of ...
Breaking Medicine News(10 mins):Health News:Healthcare Staffing Leader, Aureus Medical Group, to Exhibit at the South Carolina Physical Therapy Association Annual Conference 2Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 2Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 3Health News:Orange County Facial Plastic Surgeon Featured in Premier Magazine Focused on Beauty 2Health News:Orange County Facial Plastic Surgeon Featured in Premier Magazine Focused on Beauty 3
... (Nasdaq: AMGN ) will present at the ... May 18, 2009 at the InterContinental, Boston, Mass., beginning ... Executive Officer Kevin Sharer will present. Live audio of ... can be accessed from Amgen,s Web site, www.amgen.com ...
... risk by 35%, study finds , , WEDNESDAY, May ... medications may ease the symptoms of bronchiolitis -- a ... research suggests this treatment may reduce the risk of ... wheezing sooner and get babies back to normal feeding ...
... Plan Yields Positive ResultsCLEVELAND, May 13 DATATRAK International, ... services company focused on global eClinical solutions for the ... the first quarter of 2009. Revenue for the first ... to $2,088,000 in the same period of 2008. Gross ...
... VIEW, Calif., May 13 MAP Pharmaceuticals, Inc. (Nasdaq: ... at the Deutsche Bank Securities 34th Annual Health ... (ET) in Boston, MA.A live webcast of the presentation will ... website at http://www.mappharma.com . A replay will also be ...
... from a study of managed-care cancer patients receiving chemotherapy ... the cumulative ESA cost with Epoetin alfa (EPO) was ... The analysis, published in the Spring issue of ... by Centocor Ortho Biotech Services, LLC. The retrospective ...
... a lawsuit against the U.S. Patent and Trademark Office and Myriad ... as BRCA1 and BRCA2, which are indicators for hereditary predisposition to ... ... May 13, 2009 -- The College of American Pathologists today joined ...
Cached Medicine News:Health News:Combo Treatment Eases Wheezing in Babies 2Health News:Combo Treatment Eases Wheezing in Babies 3Health News:DATATRAK International, Inc. Announces First Quarter Results for 2009 2Health News:DATATRAK International, Inc. Announces First Quarter Results for 2009 3Health News:DATATRAK International, Inc. Announces First Quarter Results for 2009 4Health News:DATATRAK International, Inc. Announces First Quarter Results for 2009 5Health News:DATATRAK International, Inc. Announces First Quarter Results for 2009 6Health News:Retrospective Analysis Finds Treatment of Cancer Chemotherapy Patients With Epoetin Alfa Associated With Lower Drug Cost Than Darbepoetin Alfa 2Health News:Retrospective Analysis Finds Treatment of Cancer Chemotherapy Patients With Epoetin Alfa Associated With Lower Drug Cost Than Darbepoetin Alfa 3Health News:Retrospective Analysis Finds Treatment of Cancer Chemotherapy Patients With Epoetin Alfa Associated With Lower Drug Cost Than Darbepoetin Alfa 4Health News:Retrospective Analysis Finds Treatment of Cancer Chemotherapy Patients With Epoetin Alfa Associated With Lower Drug Cost Than Darbepoetin Alfa 5Health News:Retrospective Analysis Finds Treatment of Cancer Chemotherapy Patients With Epoetin Alfa Associated With Lower Drug Cost Than Darbepoetin Alfa 6Health News:CAP Joins Landmark Lawsuit Challenging Legality of Myriad Genetics Gene Patents 2
(Date:4/17/2015)... DIEGO , April 17, 2015  Trovagene, ... diagnostics, announced today that clinical data presented at ... that its urine-based Precision Cancer Monitoring ℠ ... and monitoring of EGFR T790M mutations ... Detection of EGFR T790M Mutation in Urinary ...
(Date:4/17/2015)... DUBLIN , Apr. 17, 2015 Research and ... addition of the "Medical Oxygen Systems - Global ... This report analyzes the worldwide markets for Medical ... Oxygen Concentrators, Liquid Oxygen Systems, Oxygen Cylinders & Regulators, ... analytics for the US, Canada , ...
(Date:4/17/2015)... -- Today, the Pharmaceutical Research and Manufacturers of ... companies as "We Work For Health Champions" for ... service. Established in 2009, the We ... the biopharmaceutical industry to honor employees who have ... also shown an outstanding commitment to their communities ...
Breaking Medicine Technology:Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 2Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 3Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 4Medical Oxygen Systems - 2015 Global Strategic Business Report Featuring Leading Players, Caire, Invacare & Philips Respironics 2PhRMA Applauds 2015 We Work For Health Champion Award Winners 2PhRMA Applauds 2015 We Work For Health Champion Award Winners 3
... Water Street Healthcare Partners , a strategic private equity ... it has acquired MarketLab, Inc.  Water Street,s ... specialty healthcare distribution sector.  The acquisition expands Water Street,s ... life sciences, medical devices and services to 13. ...
... -- Dehaier Medical Systems Ltd. (NASDAQ: ... in the development, assembly, marketing and sale of medical ... that it was granted three new patents by State ... ("SIPO"). The patent awards were related to the design ...
Cached Medicine Technology:Water Street Healthcare Partners Acquires MarketLab, Inc. 2Water Street Healthcare Partners Acquires MarketLab, Inc. 3Dehaier Strengthens Intellectual Property Portfolio 2Dehaier Strengthens Intellectual Property Portfolio 3
... Choose from a complete ... and AC halogen light ... cool illumination. A solid-state ... intensity, and our exclusive ...
Inquire...
... inverted microscope technology that offers you much more ... in this category. You will be impressed by ... been designed to make lab work as easy ... efficiency of your workflow. Your advantage: more time ...
... represents the most advanced motorized inverted microscope ... and optical design provides 9 access ports ... to four ports can have simultaneous access ... motorized Z-axis drive, 6-position nosepiece and light ...
Medicine Products: