Navigation Links
2 tests in combination can provide better asthma diagnosis
Date:9/24/2013

It was previously thought that the two test methods signalled the same type of asthma. But a new study, led by researchers at Uppsala University, Sweden, shows that the methods actually signal two different inflammatory processes. With the tests used in combination, the chances are probably greater for the patient to receive just the right treatment. The study is being published in the October issue of Journal of Allergy and Clinical Immunology.

Measurement of the concentration of exhaled nitric oxide (FeNO) is today a routine clinical method for determining the degree of steroid-sensitive inflammation in the airways in asthma. For many years a count of eosinophil granulocytes in the blood has also been used to support a diagnosis of asthma.

These two methods were previously thought to signal the same inflammation process in asthma. In the new study, researchers investigated the importance of these two clinically used inflammation markers with the help of information from a large American population-based database (National Health and Nutrition Examination Survey) where 12,408 individuals aged 6󈞼 were included.

The scientists were able to determine that the association between FeNO and blood eosinophils was very weak. Instead, they observed that simultaneously elevated levels of the two markers, in a synergistic way, but independently of each other, increased the likelihood of individuals reporting, for example, asthma symptoms or asthma attacks in the last year.

The results supported the researchers' hypothesis that the two markers represent two different inflammation processes.

- We therefore propose that both of these measurements be carried out in combination in order to better understand the inflammation in asthma patients. They thus constitute a better platform for selecting the proper treatment for these patients, says Kjell Alving, professor at the Department of Children's and Women's Health, Uppsala University.


'/>"/>

Contact: Kjell Alving
Kjell.Alving@kbh.uu.se
46-070-659-8870
Uppsala University
Source:Eurekalert

Related medicine news :

1. Physician Groups Call for Fewer Medical Tests
2. Range of diagnostic spinal fluid tests needed to differentiate concurrent brain diseases
3. URMC clinical trial tests new regimen for hypertension
4. Smell Tests Dont Predict Alzheimers, Study Finds
5. Are Post-Angioplasty Stress Tests Unnecessary?
6. OSHAs Safety Tests Protect Workers at Little Cost: Study
7. Gene Tests May Not Drive Patients to More Medical Care
8. Better tests for sleeping sickness
9. U.S. Advisers Say No to Routine PSA Tests for Prostate Cancer
10. Breast cancer clinical trial tests combo of heat shock protein inhibitor and hormonal therapy
11. Super-sensitive tests could detect diseases earlier
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/19/2017)... New York, NY (PRWEB) , ... June 19, 2017 , ... ... and this year, it’s going to be a humdinger. A warm winter and wet ... devour summer wedding guests. “No one wants to be swatting away pesky mosquitoes when ...
(Date:6/19/2017)... ... June 19, 2017 , ... ... to foster the international exchange of actionable insights to improve health globally through ... mission to make clinical trial management faster, easier, and less painful. Attendees can ...
(Date:6/19/2017)... ... June 19, 2017 , ... Intalere, ... its annual Emerging Technology Show at its Elevate 2017 meeting in Orlando, Fla. ... those proposing new, enhanced products and services to Intalere members. , “Intalere is ...
(Date:6/19/2017)... Lake Orion, Michigan (PRWEB) , ... June 19, ... ... with respect to fertility once they have been diagnosed with endometriosis. These women ... intercourse, but they also require a comprehensive approach that can help for preservation ...
(Date:6/19/2017)... , ... June 19, 2017 , ... ... a health care company that offers health insurance plans to families and individuals ... be the sole provider of breast pumps for Molina members effective July 2017. ...
Breaking Medicine News(10 mins):
(Date:6/1/2017)... Pa. , June 1, 2017 Nutriceutical ... and Veterinarian Recommended Solutions (VRS), and KD Pharma Group ... in Nutriceutical Holdings by KD Pharma Group. KD Pharma ... with the option to acquire the entire company. ... in KD. They are committed to growing the NH ...
(Date:5/30/2017)... May 30, 2017 Therapix Biosciences Ltd. (Nasdaq: ... in the development of cannabinoid-based drugs, today announced ... overview at three upcoming scientific and investor conferences ... Micro Invitational: ... Date:                     Wednesday, ...
(Date:5/26/2017)... SANTA BARBARA, Calif. , May 25, 2017 /PRNewswire-USNewswire/ ... the United States , Direct Relief is working ... of overdose-reversing Naloxone available at no cost to community ... and other nonprofit providers nationwide. "Pfizer ... expanding access to medicines and ensuring patient safety through ...
Breaking Medicine Technology: