Navigation Links
2 tests in combination can provide better asthma diagnosis
Date:9/24/2013

It was previously thought that the two test methods signalled the same type of asthma. But a new study, led by researchers at Uppsala University, Sweden, shows that the methods actually signal two different inflammatory processes. With the tests used in combination, the chances are probably greater for the patient to receive just the right treatment. The study is being published in the October issue of Journal of Allergy and Clinical Immunology.

Measurement of the concentration of exhaled nitric oxide (FeNO) is today a routine clinical method for determining the degree of steroid-sensitive inflammation in the airways in asthma. For many years a count of eosinophil granulocytes in the blood has also been used to support a diagnosis of asthma.

These two methods were previously thought to signal the same inflammation process in asthma. In the new study, researchers investigated the importance of these two clinically used inflammation markers with the help of information from a large American population-based database (National Health and Nutrition Examination Survey) where 12,408 individuals aged 6󈞼 were included.

The scientists were able to determine that the association between FeNO and blood eosinophils was very weak. Instead, they observed that simultaneously elevated levels of the two markers, in a synergistic way, but independently of each other, increased the likelihood of individuals reporting, for example, asthma symptoms or asthma attacks in the last year.

The results supported the researchers' hypothesis that the two markers represent two different inflammation processes.

- We therefore propose that both of these measurements be carried out in combination in order to better understand the inflammation in asthma patients. They thus constitute a better platform for selecting the proper treatment for these patients, says Kjell Alving, professor at the Department of Children's and Women's Health, Uppsala University.


'/>"/>

Contact: Kjell Alving
Kjell.Alving@kbh.uu.se
46-070-659-8870
Uppsala University
Source:Eurekalert

Related medicine news :

1. Physician Groups Call for Fewer Medical Tests
2. Range of diagnostic spinal fluid tests needed to differentiate concurrent brain diseases
3. URMC clinical trial tests new regimen for hypertension
4. Smell Tests Dont Predict Alzheimers, Study Finds
5. Are Post-Angioplasty Stress Tests Unnecessary?
6. OSHAs Safety Tests Protect Workers at Little Cost: Study
7. Gene Tests May Not Drive Patients to More Medical Care
8. Better tests for sleeping sickness
9. U.S. Advisers Say No to Routine PSA Tests for Prostate Cancer
10. Breast cancer clinical trial tests combo of heat shock protein inhibitor and hormonal therapy
11. Super-sensitive tests could detect diseases earlier
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/30/2016)... (PRWEB) , ... April 30, 2016 , ... “Aging well is a challenge for all of us, but there are ... Dr. Parul T. Kohli . “Research is showing more and more that there are simple, ... disease and disability as we age.” Top priorities Dr. Kohli’s recommends for her patients include;, ...
(Date:4/29/2016)... Dobbs Ferry, New York (PRWEB) , ... April 30, 2016 , ... ... and the Dobbs Ferry campus. The following programs will be expanding due to ... Resources Management (HRM). The expansion will begin this summer. , School ...
(Date:4/29/2016)... Hollywood, Fl (PRWEB) , ... April 29, 2016 ... ... was recently notified by the Accreditation Council for Graduate Medical Education (ACGME) that ... , This is the first accreditation of three residency programs that Memorial ...
(Date:4/29/2016)... Atlanta, Georgia (PRWEB) , ... April 29, 2016 , ... ... 60 rural hospitals across the Southeast, celebrated the signature of Gov. Nathan Deal on ... by Rep. Geoff Duncan (R - Cumming), offers a 70% tax credit to individuals ...
(Date:4/29/2016)... ... 2016 , ... The White House announced efforts yesterday to ... about their loan terms and accounts, and more protections for borrowers. The announcement ... private loans, has reached $1.3 trillion, with 43 million Americans holding student loans ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... , April 28, 2016 Dr. ... and Ste phen ... ArisGlobal®, a leading provider of cloud-based software solutions for life ... Pharmacovigilance team to bring a wealth of insight to a growing ... pharmacovigilance knowledge. George Phillips joined ArisGlobal in ...
(Date:4/28/2016)... , April 28, 2016  ValGenesis, Inc., ... Management Solutions (VLMS) today announced that a ... for sufferers of chronic kidney failure has ... manage their corporate validation process. The global ... software solution to manage their validation processes ...
(Date:4/27/2016)... 2016  Hologic, Inc. (Nasdaq: HOLX ... the fiscal second quarter ended March 26, 2016.  ... increased 41.2%, and non-GAAP diluted EPS of $0.47 ... on a reported basis, and 6.3% on a ... another good quarter, highlighted by 14.6% growth in ...
Breaking Medicine Technology: