Navigation Links
2 tests in combination can provide better asthma diagnosis
Date:9/24/2013

It was previously thought that the two test methods signalled the same type of asthma. But a new study, led by researchers at Uppsala University, Sweden, shows that the methods actually signal two different inflammatory processes. With the tests used in combination, the chances are probably greater for the patient to receive just the right treatment. The study is being published in the October issue of Journal of Allergy and Clinical Immunology.

Measurement of the concentration of exhaled nitric oxide (FeNO) is today a routine clinical method for determining the degree of steroid-sensitive inflammation in the airways in asthma. For many years a count of eosinophil granulocytes in the blood has also been used to support a diagnosis of asthma.

These two methods were previously thought to signal the same inflammation process in asthma. In the new study, researchers investigated the importance of these two clinically used inflammation markers with the help of information from a large American population-based database (National Health and Nutrition Examination Survey) where 12,408 individuals aged 6󈞼 were included.

The scientists were able to determine that the association between FeNO and blood eosinophils was very weak. Instead, they observed that simultaneously elevated levels of the two markers, in a synergistic way, but independently of each other, increased the likelihood of individuals reporting, for example, asthma symptoms or asthma attacks in the last year.

The results supported the researchers' hypothesis that the two markers represent two different inflammation processes.

- We therefore propose that both of these measurements be carried out in combination in order to better understand the inflammation in asthma patients. They thus constitute a better platform for selecting the proper treatment for these patients, says Kjell Alving, professor at the Department of Children's and Women's Health, Uppsala University.


'/>"/>

Contact: Kjell Alving
Kjell.Alving@kbh.uu.se
46-070-659-8870
Uppsala University
Source:Eurekalert

Related medicine news :

1. Physician Groups Call for Fewer Medical Tests
2. Range of diagnostic spinal fluid tests needed to differentiate concurrent brain diseases
3. URMC clinical trial tests new regimen for hypertension
4. Smell Tests Dont Predict Alzheimers, Study Finds
5. Are Post-Angioplasty Stress Tests Unnecessary?
6. OSHAs Safety Tests Protect Workers at Little Cost: Study
7. Gene Tests May Not Drive Patients to More Medical Care
8. Better tests for sleeping sickness
9. U.S. Advisers Say No to Routine PSA Tests for Prostate Cancer
10. Breast cancer clinical trial tests combo of heat shock protein inhibitor and hormonal therapy
11. Super-sensitive tests could detect diseases earlier
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 10, 2016 , ... 10 Best Water is ... leading bottled water brand owners that topped the list as a result of their ... conversion. The premier brand was Tibet 5100, a top notch water company that specializes ...
(Date:2/10/2016)... , ... February 10, 2016 , ... ... Diego, will bring together more than 200 of the country’s top healthcare executives ... future. , “The true benefit of the Forum is the provider-centric perspective, experience, ...
(Date:2/10/2016)... ... , ... Armune BioScience signed a definitive agreement with ARCpoint ... across the country. Launched in April of 2015, Apifiny is the only cancer specific, ... order volume exceeded 3,000 tests in 2015. Primary care physicians and urologists have utilized ...
(Date:2/10/2016)... ... February 10, 2016 , ... A national ... Congress and Expo event March 9-11, 2016. Hosted by Ohio's Bureau of Worker's ... , As the longest running and largest worker's compensation event in Ohio, organizers ...
(Date:2/10/2016)... ... February 10, 2016 , ... ... February 26th: Amateur & Professional Divisions - Time: 7:00pm – 10:00pm | ... | Ticket Prices $30, Social Media: http://www.USPoleSportsFed.org , Facebook: http://www.facebook.com/uspolesportsfederation ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... LONDON , February 10, 2016 ... window and M 1 receptor selectivity   ... Heptares StaR® technology, which has entered clinical development ... patients with dementia and schizophrenia.   --> ... StaR® technology, which has entered clinical development as ...
(Date:2/9/2016)... FARMINGDALE, N.Y., Feb. 9, 2016  Misonix, Inc. ... company that designs, manufactures and markets innovative therapeutic ... wound debridement, cosmetic surgery, laparoscopic surgery and other ... second quarter and the first half of fiscal ... --> --> Highlights ...
(Date:2/9/2016)... Mass. , Feb. 9, 2016  Insulet Corporation (NASDAQ: ... tubeless insulin pump technology with its OmniPod ... David A. Lemoine has been appointed to Insulet,s Board ... of nine directors, eight of whom are independent. ... 40 years of audit and finance experience and a deep ...
Breaking Medicine Technology: