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2 new cost-effective ways to predict prostate cancer
Date:9/23/2011

cer, and with a two to eight-fold increased risk of them dying from prostate cancer.

"Benign prostatic hyperplasia and prostate cancer are the most common prostatic conditions with a large number of incident and prevalent cases each year. A possible association has been debated for several years but previous studies have generated ambiguous results. Our study is the largest to date and has consistent results showing an association," research team member Dr Stig Bojesen will tell the congress.

Additional research is needed to determine whether benign prostate enlargement could be a possible cause of prostate cancer, but the results already have important implications given the large number of patients affected. "The possible clinical implication of our study might be that physicians treating men with benign prostatic hyperplasia should follow these men carefully, to ensure early diagnosis and treatment of a possible prostate cancer, thereby enhancing the chance of curative treatment. However, our study does not allow us to suggest the optimal surveillance programme for these men. This question should be addressed in future studies," says Dr Bojesen.

The second Danish study, also led by Dr rsted, looked at whether prostate-specific antigen levels could predict prostate cancer incidence and mortality in the general population.

Prostate-specific antigen is a protein produced by the prostate gland. Healthy men have low levels of the antigen in their blood, and raised levels are considered an indicator of prostate cancer as well as other conditions of the gland. However, it is largely unknown whether antigen levels in healthy men predict long-term risk of developing prostate cancer.

Researchers looked at blood collected from 4,383 men aged between 20 and 94 years of age from the general population, who had taken part in the Copenhagen City Heart Study and followed them from 1981 through to 2009. They measured baseline levels o
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Contact: Saffina Rana
saffina.rana@europe.com
ECCO-the European CanCer Organisation
Source:Eurekalert

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