Navigation Links
2 Grand Challenges Explorations grants for global health
Date:5/11/2012

The innovative research of three Northwestern University professors who are making a big difference in the highly promising area of synthetic biology has been recognized with two early-stage discovery awards from Grand Challenges Explorations, an initiative funded by the Bill & Melinda Gates Foundation.

The global health projects will focus on creating new compounds to combat malaria and on producing biosensors for low-cost, in-home diagnoses.

The prestigious awards are two of 107 Grand Challenges Explorations (GCE) grants announced this week. The funding supports scientists, researchers and entrepreneurs worldwide who are testing unconventional ideas that show great promise to improve the health of people in the developing world.

Northwestern now has received a total of three GCE grants as part of the Gates Foundation's call to "Apply Synthetic Biology to Global Health Challenges." (Synthetic biology is the design and construction of new types of biological systems.) To date, only 30 synthetic biology grants have been awarded as part of this initiative, acknowledging Northwestern as being at the forefront of its use to address global health issues.

"The Gates Foundation support allows us to pursue high-risk, high-reward projects that are utilizing cutting-edge techniques to engineer biological systems," said Keith Tyo, an investigator on all three grants. "Success on any one of these projects could result in a dramatic improvement in quality of life for millions of suffering people."

Tyo is an assistant professor of chemical and biological engineering in the McCormick School of Engineering and Applied Science.

Andreas Matouschek, professor of molecular biosciences in the Weinberg College of Arts and Sciences, and Tyo will develop synthetic compounds that target essential proteins in the Plasmodium parasite for destruction by its own protein degradation mechanisms. This strategy could lead to new treatment modalities as well as small molecule drug development efforts to combat malaria.

In the other project, Tyo and Joshua Leonard, an assistant professor of chemical and biological engineering, will work to engineer yeast-based biosensors that identify protein biomarkers in samples like blood and urine. An array of yeast strains could serve as a low-cost, in-home device providing patients with a panel of diagnostics to improve treatment and diagnosis in resource-poor settings.

Each project will receive an 18-month grant of $100,000. Successful projects have an opportunity to receive a second grant of up to $1 million.

"Grand Challenges Explorations encourages individuals worldwide to expand the pipeline of ideas where creative, unorthodox thinking is most urgently needed," said Chris Wilson, director of Global Health Discovery and Translational Sciences at the Bill & Melinda Gates Foundation. "We're excited to provide additional funding for select grantees so that they can continue to advance their idea towards global impact."

Synthetic biology researchers at Northwestern are leading a new wave of design-based biological engineering, exploring three major areas: biomolecular networks, cellular devices and therapeutics, and approaches that expand the chemistry of life. The engineers, scientists and physicians represent three schools -- McCormick, Weinberg and the Feinberg School of Medicine.


'/>"/>

Contact: Megan Fellman
fellman@northwestern.edu
847-491-3115
Northwestern University
Source:Eurekalert

Related medicine news :

1. Nearly 1 in 4 grandparents store prescription medicines where children can easily find them
2. University of Colorado Denver receives Grand Challenges Explorations funding
3. St. Michaels Hospital receives Grand Challenges Explorations funding
4. UC Santa Barbara receives Grand Challenges Explorations funding
5. The Childrens Hospital of Philadelphia receives Grand Challenges Explorations funding
6. Kids Fare Better in Crashes When Grandparents Driving: Study
7. Strength training for grandma and grandpa
8. Grand Opening of GreenProductsandGifts.com Online Store Offering Eco Friendly Gifts that are Proudly Made in the USA
9. Talon Air Adds A Brand New Cessna Grand Caravan Turbo Prop To Its Growing Private Jet Charter Fleet
10. Grandpas Decision-Making Skills May Be Just Fine
11. Penn State receives Grand Challenges Explorations grant for innovative global health research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... March 24, 2017 , ... Northridge ... now offering treatments for sleep apnea and TMJ at their office. TMJ, or ... , specifically the obstructive type, is increasingly being treated at dental offices with ...
(Date:3/24/2017)... ... 2017 , ... Empower Brokerage, located in Southlake, Texas, intends ... , In February, 2017, Empower Brokerage introduced their new “Performance Partners” program to ... teach how to maximize their sales efforts, as well as how to best ...
(Date:3/24/2017)... ... March 24, 2017 , ... “The Communion of Saints: A ... God in congregations across the United States. “The Communion of Saints” is ... who has served congregations in seven states throughout his long career of devotion ...
(Date:3/23/2017)... ... March 23, 2017 , ... Demonstrating their commitment ... more public health departments have been awarded national accreditation through the Public ... into the expanding network of communities across the nation whose health departments meet ...
(Date:3/23/2017)... ... March 23, 2017 , ... 82% of adults are unaware of the dangers that ... brush their teeth the minimum two times a day that dentists recommend. The ramifications of ... million hours of school and adults missing 164 million hours of work each year due ...
Breaking Medicine News(10 mins):
(Date:3/23/2017)... Ala. , March 23, 2017 Mosaic Life Care, based in ... the patient registration process across its network of 58 clinics, located in 22 cities, ... seeking new and innovative ways to improve the delivery of health care to its ... Continue Reading ... Mosaic Life Care St. Joseph Medical ...
(Date:3/23/2017)... March 23, 2017  Transportation Insight, a multi-modal lead ... supply chain management firm with expertise serving clients in ... Rick Zaffarano was named a 2017 ... Chain by the only publication exclusively dedicated to covering ... chain. "Rick has brought to Transportation Insight ...
(Date:3/23/2017)... March 23, 2017 As a result ... with the prevalence of allergic diseases, cutting edge ... currently revolutionising the ways in which pharmaceutical and ... 2017 promises to be both a high quality ... allergy interest groups, immunologists, research scholars and doctors. ...
Breaking Medicine Technology: