Navigation Links
2 Genes Implicated in Autism
Date:2/9/2009

Finding might lead to better diagnosis, treatment, study suggests

MONDAY, Feb. 9 (HealthDay News) -- Multiple, interacting genetic risk factors may influence the severity of autism, a new study suggests.

Massachusetts Institute of Technology researchers said they've pinpointed two genes that cause autism-like symptoms in mice. The findings support a long-held theory that more than one gene is involved in people with genetic-based autism.

The researchers said their discovery could lead to the development of drugs that target signaling mechanisms between genes that interact to cause some symptoms of autistic spectrum disorders (ASDs).

The study found that mice with mutations in two different candidate autism susceptibility genes -- PTEN and the serotonin transporter gene -- had more severe symptoms than mice with only a single mutation. Mice with a mutation in PTEN alone or in the serotonin transporter gene alone had brains that were larger than normal, while mice with mutations in both genes had even larger brains.

About 24 percent of people with autism have larger-than-normal brain size. In people with ASDs, brain size is correlated with the severity of behavioral problems, the researchers said.

The MIT study also found that female mice with a mutation in the PTEN gene had impaired sociability, and those with mutations in both PTEN and the serotonin transporter gene had more severe symptoms.

"We found that two genetic risk factors for ASDs act cooperatively in mice to influence brain size and social behavior, both of which are altered in ASDs," lead investigator Damon T. Page, a postdoctoral fellow at MIT's Picower Institute for Learning and Memory, said in an MIT news release.

"Our results provide evidence that the severity of autistic symptoms may be the product of variations in DNA in multiple locations in the genome," Page added.

The study was published in the F
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Genesis Successfully Defends Multi-Million Dollar Arbitration Filed by CRG and CRGP; Related Parties Withdraw Remaining Demands for Arbitration Against Genesis
2. Genesis Pharmaceuticals Successfully Defends Itself in a Multi-Million Dollar Arbitration, Two Other Arbitration Proceedings Against Genesis are Withdrawn
3. New genes involved in acute lymphoblastic leukemia play fundamental role in prognosis of the disease
4. Angiogenesis linked to poor survival in patients with rare type of ovarian cancer
5. Penn study finds link between Parkinsons disease genes and manganese poisoning
6. Genesis Pharmaceuticals Enters Into Agreement to Purchase Hongrui Pharmaceuticals, and Acquire 22 New Traditional Chinese Medicines
7. Cardiogenesis Announces Successful Educational Symposium at Society of Thoracic Surgeons Meeting in San Francisco
8. In Kids, Genes May Affect Leukemia Treatment
9. Popular or Not? Your Genes May Help Decide
10. Common Genes Link Bipolar Disorder, Schizophrenia
11. UCSF Researchers Use New Tools to Move in on Cancer Susceptibility Genes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)... May 28, 2015 Ticket Down is a ... match between Mexico and Argentina in early September. ... world will compete on the pitch at AT&T Stadium in ... in an international friendly on Tuesday, September 8th at 9 ... nations in the world including some of the most loved ...
(Date:5/28/2015)... Real Time Pain Relief (RTPR), makers of ... their best-selling lotion is now available in a convenient new ... FDA registered OTC pain relief product. It contains a proprietary ... Vera, Arnica, Capsicum, Chondroitin, Emu Oil, Glucosamine, Menthol and MSM. ... 1.25% – to avoid buildup of Substance P in joints ...
(Date:5/28/2015)... GA (PRWEB) May 28, 2015 Hexagon ... Inc. (BHI) , a provider of engineering, spatial data ... generate and analyze thousands of point clouds for urban ... From 2012 to 2014, the BHI Spatial Data Division ... from digital stereo aerial imagery. Collected by a variety ...
(Date:5/28/2015)... IL (PRWEB) May 28, 2015 Cancer ... program exhibited improvements in physical activity, fitness and quality ... Irwin of Yale Cancer Center and Jennifer Ligibel, MD, ... Women’s Cancers, Dana Farber Cancer Institute. The findings will ... Clinical Oncology (ASCO) Annual Meeting in Chicago. ...
(Date:5/28/2015)... The MIT Sloan Center for Information Systems Research ... of the MIT CISR research team interviewed members of ... case study about Healthcare IQ’s business model within the ... ‘Healthcare IQ: Competing as the “Switzerland” of Health Spend ... hospital financial software provider through its evolution to becoming ...
Breaking Medicine News(10 mins):Health News:Mexico vs. Argentina Tickets at AT&T Stadium: Ticket Down Slashes Ticket Prices on Argentina vs. Mexico Presale Tickets at AT&T Stadium for 9/8/15 Friendly Match 2Health News:Mexico vs. Argentina Tickets at AT&T Stadium: Ticket Down Slashes Ticket Prices on Argentina vs. Mexico Presale Tickets at AT&T Stadium for 9/8/15 Friendly Match 3Health News:Real Time Pain Relief Introduces New Four Ounce Pump Bottle for their Popular Pain Relief Lotion 2Health News:Hexagon Geospatial Supports Urban Change Detection Programs in New Mexico 2Health News:Hexagon Geospatial Supports Urban Change Detection Programs in New Mexico 3Health News:LIVESTRONG at the YMCA Program Shows Significant Gains for Cancer Survivor Participants 2Health News:LIVESTRONG at the YMCA Program Shows Significant Gains for Cancer Survivor Participants 3Health News:LIVESTRONG at the YMCA Program Shows Significant Gains for Cancer Survivor Participants 4Health News:Healthcare IQ, the “Switzerland” of Healthcare Spend Analytics, Featured in MIT Case Study 2Health News:Healthcare IQ, the “Switzerland” of Healthcare Spend Analytics, Featured in MIT Case Study 3
... taking too much supplemental calcium are on the rise, ... of the Journal of the American Society Nephrology ... calcium-alkali syndrome is growing in large part because of ... The milk-alkali syndrome arose in the early 1900s ...
... rural southern Asia are exposed every day to unsafe levels ... doubles their risks for cancer, causes cardiovascular disease, and inhibits ... The World Health Organization (WHO) has referred to the situation ... as "the largest mass poisoning of a population in history." ...
... Experts are now recommending that low-dose aspirin therapy to prevent ... younger than 50 and women younger than 60, who have ... aspirin. The new recommendations are based on an analysis ... side effects such as stomach bleeding, and to a much ...
... found if young adults were more fit, 34% of high ... (HealthDay News) -- Low levels of physical activity and fitness ... 20-year study of young adults shows. , The study, released ... print issue of the journal Hypertension , found that ...
... to play in disease detection , TUESDAY, June 1 (HealthDay ... signs of prostate cancer in human urine, adding to the ... friend. , Some scientists have questioned similar reports of dogs ... lead author of this latest study said the findings are ...
... patients who,ve been told to rest and avoid exercise can ... both during and after treatment, according to new national guidelines. ... Biostatistics and a member of the Abramson Cancer Center at ... guidelines at an educational session at the 2010 meeting of ...
Cached Medicine News:Health News:Calcium supplements: too much of a good thing? 2Health News:Researchers offer solutions to poisonous well-water crisis in southern Asia 2Health News:Researchers offer solutions to poisonous well-water crisis in southern Asia 3Health News:Aspirin recommendations changed for many younger diabetic patients 2Health News:Being Young and Sedentary Raises Hypertension Risk Later 2Health News:Being Young and Sedentary Raises Hypertension Risk Later 3Health News:Dog Sniffs Out Prostate Cancer in Small Study 2Health News:New cancer guidelines: Exercise during and after treatment is now encouraged 2Health News:New cancer guidelines: Exercise during and after treatment is now encouraged 3
(Date:5/28/2015)... 2015  Pharmaceutic Labs announces its official status ... of the FDA,s Drug Quality and Security Act. ... subject to Current Good Manufacturing Practice (CGMP) and ... the highest standards of CGMP 21 CFR Part ... comply with FDA regulations and ensure patient safety, ...
(Date:5/28/2015)... RARITAN, N.J. , May 28, 2015  Janssen ... today announced the initiation of CALLISTO, a new comprehensive ... in patients with active cancer. The studies are evaluating ... blood clots in patients with a wide range of ... the risk of venous thromboembolism (VTE), which is a ...
(Date:5/28/2015)... May 28, 2015  Cardinal Health today announced that ... & Johnson,s Cordis business for $1.944 billion in cash ... with relevant works councils and trade unions. The transaction ... States and key non-U.S. countries towards the ... customary closing conditions. Headquartered in ...
Breaking Medicine Technology:New Clinical Research Program Initiated for the Prevention and Treatment of Life-Threatening Blood Clots in Patients with Cancer 2New Clinical Research Program Initiated for the Prevention and Treatment of Life-Threatening Blood Clots in Patients with Cancer 3New Clinical Research Program Initiated for the Prevention and Treatment of Life-Threatening Blood Clots in Patients with Cancer 4New Clinical Research Program Initiated for the Prevention and Treatment of Life-Threatening Blood Clots in Patients with Cancer 5New Clinical Research Program Initiated for the Prevention and Treatment of Life-Threatening Blood Clots in Patients with Cancer 6New Clinical Research Program Initiated for the Prevention and Treatment of Life-Threatening Blood Clots in Patients with Cancer 7New Clinical Research Program Initiated for the Prevention and Treatment of Life-Threatening Blood Clots in Patients with Cancer 8New Clinical Research Program Initiated for the Prevention and Treatment of Life-Threatening Blood Clots in Patients with Cancer 9New Clinical Research Program Initiated for the Prevention and Treatment of Life-Threatening Blood Clots in Patients with Cancer 10New Clinical Research Program Initiated for the Prevention and Treatment of Life-Threatening Blood Clots in Patients with Cancer 11New Clinical Research Program Initiated for the Prevention and Treatment of Life-Threatening Blood Clots in Patients with Cancer 12Cardinal Health Binding Offer To Acquire Cordis Accepted 2Cardinal Health Binding Offer To Acquire Cordis Accepted 3Cardinal Health Binding Offer To Acquire Cordis Accepted 4
... Aug. 20 Do you currently have a study,that ... sites,recruitment tools and a budget for media but still ... is an extra set of hands to help,your sites ... assistance and consultation., "Through our Argonauta Assist(TM) service," ...
... SYDNEY, Australia, Aug. 20 /Xinhua-PRNewswire-FirstCall/ --,Pharmaceutical company Pharmaxis ... 3 clinical trial evaluating the long term safety ... no serious,adverse events attributed to the drug following ... 123 subjects started treatment with 320 mg Bronchitol ...
Cached Medicine Technology:Argonauta Assist(TM)ance: Argonauta Communications Strives to Enhance Site-Based Recruitment Efforts 212 Month Phase 3 Trial Finds Bronchitol Safe in Bronchiectasis 212 Month Phase 3 Trial Finds Bronchitol Safe in Bronchiectasis 3
... provides high quality ventilation and monitoring ... technologies of the AV2+ ventilator, breathing ... GS user-friendly and intuitive. , ... GS is the perfect introduction to ...
... facilities where space is a premium Fabius ... delivery technologies with an ergonomic and compact ... of the Draeger Infinity patient monitoring range ... environment that is a sound investment into ...
... The S/5 Aespire was developed using ... development close and continuous collaboration ... performance of the 7100 Ventilator with ... system solution designed for clinicians throughout ...
... Wound Dressing is a sterile, single use bundle ... dressing applications. The synthetic matrix absorbs excess ... contours, and entraps slough and necrotic debris within ... strands of the matrix are bound together by ...
Medicine Products: