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2 Common Blood Pressure Meds Fare Equally in Preventing Heart Woes
Date:8/27/2012

MONDAY, Aug. 27 (HealthDay News) -- In a review that compared two common heart drugs against each other, researchers found no difference between atenolol and metoprolol in terms of preventing stroke, heart attack or heart failure for patients with high blood pressure who were placed on the medications.

Atenolol (Tenormin) and metoprolol tartrate (Lopressor) are beta blockers that are widely used to treat high blood pressure and heart problems. Previous research has suggested that atenolol might be less effective than other high blood pressure drugs for preventing cardiovascular events in patients with high blood pressure.

In this study, researchers reviewed the medical records of nearly 121,000 U.S. patients with high blood pressure but no history of heart disease who started taking one of the two drugs between 2000 and 2009. Atenolol was used by about 10 times more patients than metoprolol.

During a follow-up averaging about five years, there was no statistically significant difference in rates of heart attack, stroke or heart failure between the two groups of patients.

"In conclusion, we found no differences in [heart] event rates ... with either atenolol or metoprolol," said review author Emily Parker, of HealthPartners Institute for Education and Research in Minneapolis, and colleagues. However, the researchers added that the findings "should be interpreted cautiously, since there have been no trials comparing these two beta blockers directly."

Two experts not connected to the study said patients have many options for treating high blood pressure.

"Like many of my colleagues, I also use beta blockers as an add-on antihypertensive strategy for those patients being treated for hypertension and not yet having other cardiac problems," said Dr. David Friedman, chief of heart failure services at North Shore-LIJ's Plainview Hospital, in Plainview, N.Y. He added, however, that "when it comes to treating bl
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