Navigation Links
2 BUSM faculty receive Alzheimer's disease grants
Date:7/11/2013

(Boston) - David Harris, MD, PhD, chair and professor of biochemistry and Benjamin Wolozin, MD, PhD, professor of pharmacology and experimental therapeutics and neurology at Boston University School of Medicine (BUSM), have received Massachusetts Neuroscience Consortium (MNC) Awards. Each will receive a $250,000 grant allowing their teams to explore new therapeutic targets for Alzheimer's disease.

Harris is developing a novel approach to the therapy of Alzheimer's disease based on targeting a newly recognized molecular pathway responsible for neurodegeneration. Based on this approach, drug compounds have the potential to overcome some of the limitations of existing medications. Current treatments are largely ineffective and do not halt the cognitive decline associated with the disease.

"This award will significantly enhance our ability to develop improved therapies for Alzheimer's disease by allowing us to interact with industry partners, which is an important element of drug development," said Harris.

Harris' laboratory at BUSM investigates the molecular and cellular mechanisms underlying two classes of human neurodegenerative disorders: prion diseases and Alzheimer's disease. Prion and Alzheimer's diseases are part of a larger group of neurodegenerative disorders, including Parkinson's, Huntington's and several other diseases.

Wolozin is developing compounds that inhibit aggregation and toxicity caused by TDP-43, a protein that forms aggregates in Alzheimer's disease as well as other diseases, such as amyotrophic lateral sclerosis and frontotemporal dementia. He is known for his Alzheimer's research, which focuses on the role of cholesterol in Alzheimer's disease and investigating mechanisms in which statins may impact the pathophysiology of the disease.

"This grant emphasizes the importance of collaboration between BUSM and development programs at major pharmaceutical companies in the Boston area," said Wolozin.

Principal Investigator of the project, Wolozin is working with Marcie Glicksman, PhD, and Kevin Hodgetts, PhD, co-directors of the Laboratory for Drug Discovery in Neurodegeneration (LDDN) at Brigham and Women's Hospital. The teams will divide the work between biology and chemistry.


'/>"/>

Contact: Gina Orlando
gina.orlando@bmc.org
617-638-8490
Boston University Medical Center
Source:Eurekalert

Related medicine news :

1. Faculty of 1000 announces partnership between F1000Prime and docwise
2. Creighton University Welcomes New Faculty Member to Master of Public Health Program
3. Faculty List for Continuing Medical Education (CME) Conference 17th Annual Conference on Hypertension, Diabetes and Dyslipidemia Released by Continuing Education Company
4. 8th edition of LSUHSC facultys textbook published
5. Concordia University, Nebraska Faculty Member Headed to Guatemala for Mission Trip
6. Renowned medical genetics pioneer to join LA BioMed faculty
7. MCG faculty member, former hostage returns to Kuwait as Fulbright Scholar
8. Radiation Research Society honors 2 faculty
9. RIT receives $3.2 million award from the NSF to advance female faculty
10. Faculty from UCLA Center for Autism Research and Treatment receive multiple NIH awards
11. College biology faculty named Leadership Fellows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... ... ... TherapySites, the leading website and online marketing ... Association. This new relationship allows TherapySites to continue to extend their online ... and promotional offers. , "TCA is extremely excited about this new partnership, as ...
(Date:6/27/2016)... ... ... TopConsumerReviews.com recently awarded their highest five-star rating to Best Buy Eyeglasses, an ... United States and Canada wear eyeglasses. Once considered to be a purely functional part ... fashion statement. Even celebrities use glasses as a way of creating an iconic image—like ...
(Date:6/26/2016)... ... June 26, 2016 , ... Pixel Film Studios Released ProSlice Levels, ... editors can give their videos a whole new perspective by using the title ... Pixel Film Studios. , ProSlice Levels contains over 30 Different presets to choose ...
(Date:6/26/2016)... ... June 26, 2016 , ... Many women are confused ... endometriosis. These women need a treatment plan to not only alleviate symptoms and ... help for preservation of fertility and ultimately achieving a pregnancy. The specialists at ...
(Date:6/25/2016)... ... , ... The temporary closing of Bruton Memorial Library on June 21 due to a possible ... often overlooked aspect of head lice: the parasite’s ability to live away from a human ... but a necessary one in the event that lice have simply gotten out of control. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... -- , , , WHEN: , ... , , , LOCATION: , , , Online, with free ... EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice President ... Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... is witnessing an exceptional era. Several new demand spaces, such as ...
(Date:6/23/2016)... , June 23, 2016  Guerbet announced today ... Inc.,s Supplier Horizon Award . One ... Guerbet was recognized for its support of Premier members ... through clinical excellence, and commitment to lower costs. ... receive this recognition of our outstanding customer service from ...
(Date:6/23/2016)... -- The Biotechnology industry might still be ... opportunities to investors. Stock-Callers.com assesses the recent performances of ... XON ), Vertex Pharmaceuticals Inc. (NASDAQ: ... ), and Regeneron Pharmaceuticals Inc. (NASDAQ: REGN ... complimentary trade alerts at: http://stock-callers.com/registration ...
Breaking Medicine Technology: