Navigation Links
2 BUSM faculty receive Alzheimer's disease grants
Date:7/11/2013

(Boston) - David Harris, MD, PhD, chair and professor of biochemistry and Benjamin Wolozin, MD, PhD, professor of pharmacology and experimental therapeutics and neurology at Boston University School of Medicine (BUSM), have received Massachusetts Neuroscience Consortium (MNC) Awards. Each will receive a $250,000 grant allowing their teams to explore new therapeutic targets for Alzheimer's disease.

Harris is developing a novel approach to the therapy of Alzheimer's disease based on targeting a newly recognized molecular pathway responsible for neurodegeneration. Based on this approach, drug compounds have the potential to overcome some of the limitations of existing medications. Current treatments are largely ineffective and do not halt the cognitive decline associated with the disease.

"This award will significantly enhance our ability to develop improved therapies for Alzheimer's disease by allowing us to interact with industry partners, which is an important element of drug development," said Harris.

Harris' laboratory at BUSM investigates the molecular and cellular mechanisms underlying two classes of human neurodegenerative disorders: prion diseases and Alzheimer's disease. Prion and Alzheimer's diseases are part of a larger group of neurodegenerative disorders, including Parkinson's, Huntington's and several other diseases.

Wolozin is developing compounds that inhibit aggregation and toxicity caused by TDP-43, a protein that forms aggregates in Alzheimer's disease as well as other diseases, such as amyotrophic lateral sclerosis and frontotemporal dementia. He is known for his Alzheimer's research, which focuses on the role of cholesterol in Alzheimer's disease and investigating mechanisms in which statins may impact the pathophysiology of the disease.

"This grant emphasizes the importance of collaboration between BUSM and development programs at major pharmaceutical companies in the Boston area," said Wolozin.

Principal Investigator of the project, Wolozin is working with Marcie Glicksman, PhD, and Kevin Hodgetts, PhD, co-directors of the Laboratory for Drug Discovery in Neurodegeneration (LDDN) at Brigham and Women's Hospital. The teams will divide the work between biology and chemistry.


'/>"/>

Contact: Gina Orlando
gina.orlando@bmc.org
617-638-8490
Boston University Medical Center
Source:Eurekalert

Related medicine news :

1. Faculty of 1000 announces partnership between F1000Prime and docwise
2. Creighton University Welcomes New Faculty Member to Master of Public Health Program
3. Faculty List for Continuing Medical Education (CME) Conference 17th Annual Conference on Hypertension, Diabetes and Dyslipidemia Released by Continuing Education Company
4. 8th edition of LSUHSC facultys textbook published
5. Concordia University, Nebraska Faculty Member Headed to Guatemala for Mission Trip
6. Renowned medical genetics pioneer to join LA BioMed faculty
7. MCG faculty member, former hostage returns to Kuwait as Fulbright Scholar
8. Radiation Research Society honors 2 faculty
9. RIT receives $3.2 million award from the NSF to advance female faculty
10. Faculty from UCLA Center for Autism Research and Treatment receive multiple NIH awards
11. College biology faculty named Leadership Fellows
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2017)... ... May 26, 2017 , ... Mediaplanet is proud to announce the ... USA Today, which will educate readers on how to take care of all aspects ... focus is placed on melanoma. Dancing with the Stars professional, Witney Carson, shares her ...
(Date:5/26/2017)... ... May 26, 2017 , ... Somnoware, a leading provider of ... with its Somnoware Sleep Device Interface (SDI). Somnoware SDI is a sleep device ... this platform, initializing devices and importing studies are just one-click operations. This plugin ...
(Date:5/26/2017)... (PRWEB) , ... May 26, 2017 , ... After raising ... Antzy Top gadget will continue to be available at a discounted crowdfunding price on ... with stress wherever they are, I also wanted to bring a fidget toy to ...
(Date:5/26/2017)... ... May 26, 2017 , ... “When the Stars Lead Home”: a poignant ... of published author Laura Weigel Douglas, an avid reader who lives in the Pacific ... sometimes feels like Green Hills Adventure Camp. She couldn’t be more grateful. , Twelve-year ...
(Date:5/26/2017)... (PRWEB) , ... May 26, 2017 , ... Water damage ... Lee, New Jersey School District had left education officials with a number of critical ... replacement of the flooring had to be accomplished with little or no disruption to ...
Breaking Medicine News(10 mins):
(Date:5/9/2017)... , May 9, 2017  Oramed Pharmaceuticals Inc. ... a clinical-stage pharmaceutical company focused on the development ... the Canadian Intellectual Property Office has granted Oramed ... Administration of Exenatide". The patent covers Oramed,s invention ... GLP-1 is an incretin hormone that stimulates ...
(Date:5/6/2017)... Texas , May 5, 2017   Provista , ... with more than 200,000 customers, today announced Jim Cunniff ... a wealth of executive and business experience to Provista, including ... compounding pharmacy in California . He assumed ... "Jim is a great fit for Provista," says ...
(Date:5/4/2017)... 2017  A recent study published in the ... light as a means of disinfection anesthesia workstations ... bioburden on anesthesia workstations. In the study, UVC ... medical equipment surfaces contaminated with three (3) organisms ... study further validates the body of literature supporting ...
Breaking Medicine Technology: