Navigation Links
19th century therapy for Parkinson's disease may help patients today
Date:4/19/2012

(CHICAGO) In the 19th century, Jean-Martin Charcot, the celebrated neurologist, developed a "vibration chair," to relieve symptoms of Parkinson's disease. Charcot reported improvements in his patients, but he died shortly thereafter and a more complete evaluation of the therapy was never conducted. Now, a group of neurological researchers at Rush University Medical Center have replicated his work in a study to see if Charcot's observation holds true against modern scientific testing.

Results from the study indicate that while vibration therapy does significantly improve some symptoms of Parkinson's disease, the effect is due to placebo or other nonspecific factors, and not the vibration. The findings are published in the April issue of Journal of Parkinson's Disease.

"We attempted to mimic Charcot's protocol with modern equipment in order to confirm or refute an historical observation," explains lead investigator Christopher G. Goetz, MD, director of the Parkinson's disease and Movement Disorders Center at Rush. "Both the treated group and the control group improved similarly, suggesting other factors had an effect on Parkinson's disease motor function."

Charcot's patients told him that during long carriage rides or train journeys, uncomfortable or painful symptoms of Parkinson's disease seemed to disappear, and the relief lasted quite some time after the journey. He developed a chair that mimicked the continuous jerking of a carriage or train.

Goetz and his colleagues randomly assigned 23 patients to either a vibrating chair or the same chair without vibration. During the treatment sessions, both groups of study participants listened to a relaxation CD of nature sounds. Study participants underwent daily treatment for a month.

The patients in the vibration treatment group showed significant improvement in motor function after daily 30-minute treatments for four weeks. Although not as high, motor function scores for the no vibration group also improved significantly. Both groups showed similar and significant improvement in depression, anxiety, fatigue, and nighttime sleep and both groups reported similar high satisfaction with their treatment.

"Our results confirm Charcot's observation of improvement in Parkinson's disease symptomology with chronic vibration treatment, but we did not find the effect specific to vibration," said Goetz. "Instead, our data suggest that auditory sensory stimulation with relaxation in a lounge chair or simply the participation in a research protocol has equivalent benefit as vibration on motor function."

"While we can agree that our results may not change scientific thinking on treatment mechanisms, our results will allow clinicians to guide patients to at least one apparatus that is safe and associated with objective changes in parkinsonian impairment scores," said Goetz. "Charcot's advice to colleagues resonates as one places vibration therapy in the context of potential options for patients. 'It is no small gain to be able to relieve the sufferers of paralysis agitans.'"


'/>"/>

Contact: Deb Song
deb_song@rush.edu
312-942-0588
Rush University Medical Center
Source:Eurekalert

Related medicine news :

1. Solving mystery of how sulfa drugs kill bacteria yields 21st century drug development target
2. Breastfeeding saved babies in 19th- Century Montreal
3. Century-old brains may hold future of treatment for mentally ill, Indiana University pathologist says
4. Nationwide trends for sepsis in the 21st century
5. ASCO: Glioblastoma in the 21st century: Wealthier patients living longer than poorer patients
6. Tests on century-old equipment show how far X-rays have come
7. 19th Century Polygamy Meant Fewer Kids Per Wife, Data Shows
8. Polygamy hurt 19th century Mormon wives evolutionary fitness
9. Famed neurosurgeons century-old notes reveal modern style admission of medical error
10. Social class and changes in mortality from liver cirrhosis over the 20th Century
11. EcoFocus Study Identifies Opportunities for Companies to Target the New 21st Century Mom
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/9/2016)... ... December 09, 2016 , ... ... pharmaceutical inserts and outserts. As a means of expanding capabilities Flottman has ... enable Flottman to individually code professional inserts (PIs) and patient package inserts (PPIs) ...
(Date:12/9/2016)... York, NY (PRWEB) , ... December 09, 2016 , ... ... raises awareness for organ transplantation while encouraging readers to sign up as an organ ... a lifesaving organ transplant. , An organ donor can save up to 8 ...
(Date:12/8/2016)... (PRWEB) , ... December 08, 2016 , ... ... will become Quality Insights beginning January 1, 2017. The name change aligns ... commitment to measuring and improving health care quality. , “We are very proud ...
(Date:12/8/2016)... Pa. (PRWEB) , ... December 08, 2016 , ... ... Medicine Southern Chester County, a Property owned by an affiliate of Seavest, has ... square foot Penn Medicine Southern Chester County ambulatory care center (ACC) was named ...
(Date:12/8/2016)... ... December 08, 2016 , ... Premier Fitness Camp (PFC) and The ... ultimate weight loss and wellness program, at their world headquarters of Omni La Costa ... and long-term results to anyone seeking weight loss, personal development, a healthy lifestyle, or ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... LLC announced today that Steven E. Dawson has been appointed as chief ... Photo - http://photos.prnewswire.com/prnh/20161209/447552 ... Harmar ... Mr. Dawson,s executive career includes leadership roles managing and executing transformation, ... brings to the company deep operational and leadership expertise, a strong financial ...
(Date:12/9/2016)... Research and Markets has announced the addition of the ... ... travel vaccines market to grow at a CAGR of 6.83% during ... and the growth prospects of the global travel vaccines market for ... generated from the sales of various vaccines administered to actively immunize ...
(Date:12/8/2016)... 8, 2016 IRIDEX Corporation (NASDAQ: IRIX ... shares of common stock, $0.01 par value (the "Offering" with ... offering.  The final terms of the Offering will depend on ... there can be no assurance as to whether or when ... use the net proceeds it will receive from this offering ...
Breaking Medicine Technology: