Navigation Links
18F-DG PET/CT can highly increase the detection of colorectal cancer
Date:10/10/2007

Combined positron emission tomography and computed tomography (PET/CT) is currently widely used in the clinical diagnosis of cancer to provide functional and morphological imaging. The value of PET/CT in detection of the recurrence and metastasis of colorectal cancer (CRC) was recently confirmed in an article appearing in the October 7 issue of the World Journal of Gastroenterology.

The research performed at the Department of Medical Oncology, Jinling Hospital, China. Dr. Chen and his colleagues observed a total of 68 postoperative CRC patients, 48 male and 20 female, who were examined in the Jinling Hospital PET/CT Center between August 2004 and August 2006. After PET/CT imaging, recurrence and/or metastasis were confirmed in 82.4% (56/68) of the patients, with 91.7% (22/24) cases with elevated serum CEA levels. PET/CT detected more lesions than CT or ultrasonography alone in 30.4 % (17/56) of the cases of recurrence and/or metastasis.

CRC is the most common gastrointestinal malignancy, and its incidence and mortality are rising in China. Radical resection remains as the major means of CRC management, but recurrence and/or metastasis occurs in 30 to 50 percent of patients after surgery. An accurate diagnosis of postoperative local recurrence and distant metastasis is crucial for prescribing optimal individualized management and thus elevating the survival rate. However, CRC is not normally detected by traditional imaging techniques, such as CT, magnetic resonance imaging (MRI) and ultrasonography, until the lesion reaches a considerable size.

PET/CT imaging provides a whole-body overview in one examination, and can detect abnormal glucose metabolism before the morphological changes of a lesion can be identified. In the current study, the treatment plans of 16.2% (11/68) of the cases were altered based on the PET/CT findings. Local metastasis focus was detected in the liver or lung in three cases; accordingly surgical resections were conducted instead of intravenous chemotherapy. Conversely, disseminated metastases were detected in six cases, and thus intravenous or oral chemotherapy was prescribed instead of surgery.

To most CRC patients, the cost of PET/CT is more expensive than traditional imaging techniques. However, Dr. Chen believes an optimal, individualized treatment plan is the most important aspect of treating this malignancy, as such a plan can indeed prolong the life and lessen both the mental and economical burdens of patients.

The researchers demonstrated the superiority of 18F-DG PET/CT in the imaging diagnosis of the postoperative recurrence and/or metastasis of CRC by conducting a retrospective study of 68 patients. Their findings are valuable when considering the choice of imaging techniques for detecting the recurrence and/or metastasis of CRC.


'/>"/>

Contact: You-De Chang
y.d.chang@wjgnet.com
86-108-538-1892
World Journal of Gastroenterology
Source:Eurekalert

Related medicine news :

1. PET/CT: The Best Test for Women With Ovarian Cancer
2. MRI with nanoparticles highly sensitive in detecting prostate cancer metastases
3. Highly Educated More Prone To Parkinsons Disease
4. Alzheimers Disease Progresses Rapidly In Highly Educated
5. Mapping Of Brain Highly Beneficial For Safer Brain Tumor Surgery
6. Highly Pure Form Of heroin Proving To be lethal Killer
7. Highly Potent TB Strain Plays Favorites Targeting Specific Ethnic Groups
8. Threat posed by highly resistant strains of TB
9. Highly-Concentrated Botulinum Preparation Can Result in Severe Illness
10. Therapy Modulates Highly Sensitized Immune System to Let Mother Give Kidney to Daughter
11. Act Now To Cleanse Highly Polluted River Hindon, Says Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... ... ... “Knowledge is God’s Lighthouse”: a moving and colorful collection of prayers that ... of published author, Gene Gaapf, a retired truck driver, and a long-time writer, whose ... since high school and have many different titles,” Gaapf mentions about his different works. ...
(Date:1/19/2017)... ... January 19, 2017 , ... ... an On-demand E-learning system for Clinical and Regulatory education for Physicians, Physician ... on Aerolib`s successful education methodology of Disease Specific Documentation Improvement. , The ...
(Date:1/19/2017)... ... , ... This month, the CEO and Clinical Director of Sober Living Outpatient, ... in Delray Beach, Florida has been changed from Sober Living Outpatient to ‘SLO Recovery ... Hoffman and Chris Farley are dying from heroin overdoses, but thousands of unnamed kids ...
(Date:1/19/2017)... CA (PRWEB) , ... January 19, 2017 , ... Cosmetic ... of plastic surgery procedures in order to make it easier for their readers to ... of the body they impact as well as the techniques used on those particular ...
(Date:1/19/2017)... ... January 19, 2017 , ... MB Business ... new $11,250,000 senior credit facility to Sunrise, Florida-based Management Health Systems, LLC, dba ... to facilitate a recapitalization of MedPro led by Harren Equity Partners. Brightwood ...
Breaking Medicine News(10 mins):
(Date:1/19/2017)... January 18, 2017 , , Marks E-QURE ... distribution agreement, following similar agreements in Israel ... Wound care is $2 5 billion ... E-QURE Corp. (OTCQB: EQUR), a leader in medical devices for the treatment of ... Médica Equipos Médicos S.A.S. (TeckMedica) in Colombia for the ...
(Date:1/19/2017)... , Jan. 18, 2017 The drug ... billion by 2021 from USD 1,179.20 billion in 2016, ... Increasing prevalence of chronic diseases, increasing demand for ... factors driving the growth of this market. Whereas, self-administration ... generic drugs offer significant growth opportunities for players operating ...
(Date:1/18/2017)... and PUNE, India , January 18, 2017 ... Market Research, titled, "Breast Imaging Technologies Market by Type: Global ... breast imaging technologies market size was valued at $2,544 million ... 2022, growing at a CAGR of 8.4% from 2016 to ... Europe together accounted for over three-fourths market share ...
Breaking Medicine Technology: