Navigation Links
15-Point Test Gauges Alzheimer's Risk
Date:5/13/2009

In older volunteeers, the screening tool predicted start of dementia

WEDNESDAY, May 13 (HealthDay News) -- Researchers have developed a 15-point test that can identify the risk for developing Alzheimer's disease in older people.

But the tool, which involves both simple questions as well as complex physiological testing, may not be practical for clinical use.

"Some of the points on there are fairly easy, such as age and mental status exams. We do those already in the clinic," said Dr. Michael Palm, an assistant professor of neuroscience and experimental therapeutics and internal medicine at the Texas A&M Health Science Center College of Medicine. "But, as far as the screening tests, I don't think we can order MRI and genetic testing on everybody who starts getting older."

And the simpler parts of the system, Palm added, are already routinely used in screening for Alzheimer's.

Palm was not involved with the study, conducted by researchers at the University of California, San Francisco, and published online May 13 issue in the journal Neurology.

According to the authors of the study, which was supported by the U.S. National Institutes of Health, while there are ways to predict dementia two decades in the future in middle-aged individuals, there is no system to predict onset of the disease later in life.

The study involved 3,375 people, mean age 76, none of whom had dementia when they were enrolled. About 60 percent were women, and 15 percent were black.

Risk factors in the index included: older age; poor performance on cognitive tests; low body-mass index; having the predisposing apolipoprotein E (APOE) gene; abnormal MRI findings; thicker carotid artery measurements and other vascular indications; slowness buttoning a shirt or performing other physical tasks; and not drinking alcohol.

Only 4 percent of participants with low scores went on to develop dementia (Alzheimer's and other forms of dementia including vascular dementia) over the next six years, versus 23 percent of those with mid-range scores and 56 percent of those with high scores.

Not surprisingly, older age and poorer performance on cognitive tests were the strongest indicators of future dementia.

Other risk factors were more surprising, said Dr. Gary Kennedy, director of geriatric psychiatry at Montefiore Medical Center in New York City. Those included lower body-mass index and abstaining from alcohol, which contradict previous findings.

Still, Kennedy agreed with Palm when he pointed out that some aspects of the tool are not likely to be adopted on a large scale, such as an MRI.

More information

The Alzheimer's Association has more on risk factors for this disease.



SOURCES: Gary J. Kennedy, M.D., director, geriatric psychiatry, Montefiore Medical Center, New York City; Michael Palm, M.D., assistant professor, neuroscience and experimental therapeutics and internal medicine, Texas A&M Health Science Center College of Medicine, and director, Parkinson's and Headache programs, Texas Brain and Spine Institute, Bryan; May 13, 2009, Neurology, online


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New Poll Gauges South Floridas Views on Health Care
2. Alzheimers Research Target May Be a Dead End
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
15-Point Test Gauges Alzheimer's Risk 
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... ... agency serving communities in the greater Dallas, Miami, and Raleigh regions, is organizing ... fighting to overcome a rare and deadly chromosome abnormality. , After struggling since ...
(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of Family Medicine's (ABFM) ... and Chief Executive Officer, succeeding Dr. James C. Puffer upon his retirement. Dr. Newton ... until Dr. Puffer’s retirement at the end of 2018. Upon assuming the role of ...
(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the ... national organization of elder law and special needs planning attorneys. “Membership in ElderCounsel helps ... provides a forum to network with elder law attorneys nationwide,” said Somekh. , ...
(Date:10/13/2017)... New York, NY (PRWEB) , ... October 13, 2017 , ... ... most influential people in business to advocate for action towards gender equality at their ... 18,000 views from around the globe, and reached a social audience of over 3 ...
(Date:10/13/2017)... VA (PRWEB) , ... October 13, 2017 , ... ... of DevOps and Agile Software Development, has been awarded a contract by the ... Blanket Purchase Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies ...
Breaking Medicine News(10 mins):
(Date:10/4/2017)...  According to the Centers for Disease Control and Prevention (CDC), ... Urgent Care is helping communities across Massachusetts , ... offering no-cost* flu shots through the end of the month. ... regulations. ... a flu shot is by the end of October, according to the ...
(Date:10/2/2017)... , Oct. 2, 2017  Eli Lilly and ... financial results for the third quarter of 2017 on ... conference call on that day with the investment community ... The conference call will begin at 9 ... can access a live webcast of the conference call ...
(Date:10/2/2017)... 2, 2017 The Rebound mobile app is poised ... reverse the tide of prescription drug addiction. The app empowers ... intake and stepping down their dosage in a safe, controlled ... December 2017; the first 100,000 people to sign up will ... http://www.rebound-solution.com/ ...
Breaking Medicine Technology: