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10 years of health innovation in Africa
Date:6/5/2013

re needed to support this strategy.

DNDi and a number of other new partnership initiatives set up during the last decade are bringing together the public and private sectors, in collaboration with WHO, TDR, and others to develop such new health tools. While not the ultimate solution to R&D gaps, these new models contribute significantly to the fight against neglected diseases.

'DNDi has developed six new treatments for four neglected diseases in the past decade, but there are still other neglected diseases that continue to lack good treatment options. While this progress is a good start, the treatments delivered are far from optimal. We have not yet developed new modern drugs which could change the history of certain neglected diseases,' said Dr Bernard Pcoul, Executive Director of DNDi. 'To truly fight neglect, we must push for more innovation and access of new treatments together with adequate coordination with control programmes. Progress to date shows this can be done in and with countries in Africa.'

DNDi and partners in Africa have established two regional R&D disease networks: the Leishmaniasis East Africa Platform (LEAP), launched in 2003 in Khartoum, Sudan; and the Human African Trypanosomiasis (HAT) Platform, launched in 2005 in Kinshasa, Democratic Republic of the Congo. LEAP was instrumental in the development of the combination drug SSG&PM (sodium stibogluconate and paromomycin) for the treatment of visceral leishmaniasis (kala azar) in East Africa, while the HAT Platform played a major role in the development of NECT (nifurtimox-eflornithine combination therapy) for the treatment of late-stage sleeping sickness.

'Around the world we are moving ahead in leaps and bounds, as ten years ago, good clinical practice was not the norm. Africa has moved very quickly in in this field and in the regulatory area and in ethics review. We need very strong clinical and regulatory practice to do good R&D,' said Dr Charles Mgone, E
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Contact: Violaine Dällenbach
vdallenbach@dndi.org
41-794-241-474
Drugs for Neglected Diseases Initiative
Source:Eurekalert

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