Navigation Links
10-fold life span extension reported in simple organism
Date:1/11/2008

Biologists have created bakers yeast capable of living to 800 in yeast years without apparent side effects.

The basic but important discovery, achieved through a combination of dietary and genetic changes, brings science closer to controlling the survival and health of the unit of all living systems: the cell.

Were setting the foundation for reprogramming healthy life, said study leader Valter Longo of the University of Southern California.

The study is scheduled to appear in the Jan. 25 issue of the journal PLOS Genetics. A companion study, showing that the same genetic changes in yeast reverse the course of an accelerated aging syndrome, appears in the Jan. 14 issue of the Journal of Cell Biology.

Longos group put bakers yeast on a calorie-restricted diet and knocked out two genes, RAS2 and SCH9, that promote aging in yeast and cancer in humans.

We got a 10-fold life span extension that is, I think, the longest one that has ever been achieved in any organism, Longo said. In 2005, the same research group reported a five-fold life span extension in the journal Cell. Normal yeast organisms live about a week.

I would say 10-fold is pretty significant, said Anna McCormick, chief of the genetics and cell biology branch at the National Institute on Aging and Longos program officer.

The NIA funds such research in the hope of extending healthy life span in humans through the development of drugs that mimic the life-prolonging techniques used by Longo and others, McCormick added.

Bakers yeast is one of the most studied and best understood organisms at the molecular and genetic level. Remarkably in light of its simplicity, yeast has led to the discovery of some of the most important genes and pathways regulating aging and disease in mice and other mammals.

A study recently published in Cell (Issue 130, pages 247-258, 2007) reported that a mouse with a gene mutation first
'/>"/>

Contact: Carl Marziali
marziali@usc.edu
213-219-6347
University of Southern California
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. KV Pharmaceutical Company Announces NYSE Listing Extension
2. CSC Signs Extension to Managed Applications Services Agreement With Sun Microsystems
3. Blunt Applauds Passage of Republican-Crafted SCHIP Extension
4. Kidney Patient Organizations, Kidney Community Come Out in Support of Medicare Secondary Payer (MSP) Extension
5. Ortho Organizers(R) Introduces Product Line Extension - Rectangular Super Elastic Nitanium(R) Black Ti(TM) Archwire
6. AstraZeneca Receives Six Months Pediatric Exclusivity Patent Extension for ARIMIDEX(R) (anastrozole) from the FDA
7. KARL STORZ and Global Care Quest Announce Extension of Marketing Agreement
8. Holiday Decorating and Extension Cords
9. NetSuite Partners Introduce New Vertical Versions of NetSuite and Horizontal Extensions to Core NetSuite Functionality
10. Imagentix Offers Extension of Warrants
11. Mylan Announces Extension of Tender Offers for Its 5.750% Senior Notes due 2010 and 6.375% Senior Notes due 2015
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2015)... ... July 28, 2015 , ... Carol McFarland, ... with discussion and demonstration of specific rehabilitation exercises and treatment protocols in the ... surgical process with an extensive interview conducted by Carol with a board certified ...
(Date:7/28/2015)... ... July 28, 2015 , ... Cupertino orthodontist , ... revolutionary orthodontic treatment that allows patients to straighten teeth even without braces. “The ... imaging technology. You wear each set of aligners for about two weeks, removing ...
(Date:7/27/2015)... ... 2015 , ... Almost a year ago, the US Preventive Services Task ... who are obese and those who are overweight with at least one cardiovascular risk ... any commercial health plan with a program year start after August 26, 2015. But ...
(Date:7/27/2015)... (PRWEB) , ... July 27, 2015 , ... ... and diabetes, are associated with smaller regional brain volumes that may be early ... the journal Radiology. , “We already know that vascular risk factors damage the ...
(Date:7/27/2015)... ... July 28, 2015 , ... ... as a 2015 Professional Woman of the Year. Ms. Baum-Lappe is recognized ... organization of professional women in the country, spanning virtually every industry and profession, ...
Breaking Medicine News(10 mins):Health News:North American Seminars Introduces a New OT PT PTA Online Continuing Education Course on the Treatment of Post Surgical Cervical and Lumbar Spine Patients 2Health News:North American Seminars Introduces a New OT PT PTA Online Continuing Education Course on the Treatment of Post Surgical Cervical and Lumbar Spine Patients 3Health News:North American Seminars Introduces a New OT PT PTA Online Continuing Education Course on the Treatment of Post Surgical Cervical and Lumbar Spine Patients 4Health News:North American Seminars Introduces a New OT PT PTA Online Continuing Education Course on the Treatment of Post Surgical Cervical and Lumbar Spine Patients 5Health News:North American Seminars Introduces a New OT PT PTA Online Continuing Education Course on the Treatment of Post Surgical Cervical and Lumbar Spine Patients 6Health News:Cupertino Invisalign Dentist, Dr. Setareh Mozafari, is Now Offering Complimentary Consultations for Invisalign 2Health News:How Digital Therapeutics Can Help Payers Out of Regulatory Fix 2Health News:How Digital Therapeutics Can Help Payers Out of Regulatory Fix 3Health News:RSNA: Specific Cardiovascular Risk Factors May Predict Alzheimer’s Disease 2Health News:RSNA: Specific Cardiovascular Risk Factors May Predict Alzheimer’s Disease 3Health News:NAPW Inducts Gilda Baum-Lappe, Journalist / Correspondent of Hollywood Foreign Press Association Into its VIP Woman of the Year Circle 2
... , ST. PAUL, Minn., Aug. 11 Though total ... - nearly twice the rate of inflation - pharmacy spending has increased ... Therapeutics (Prime), a thought leader in pharmacy benefit management. According to a ... time for Prime clients. , , According to the ...
... , , PRINCETON, N.J., ... subsidiary of Ranbaxy Laboratories Limited (RLL), announced today that RLL ... Administration to manufacture and market Sumatriptan Succinate Tablets, 25 mg ... Drugs, U.S. Food and Drug Administration, has determined the Ranbaxy ...
... Aug. 11 /PRNewswire-Asia/ -- Winner Medical Group Inc.,(OTC Bulletin Board: ... for the third quarter ended June 30, 2009.,The Company,s results ... States Securities and Exchange Commission. , , ... sales revenue increased by 5.56% over the third quarter of, ...
... , , ATLANTA, Aug. 11 ... responsibility, yet the lack of it is rampant. Some people are ... for being. , , "Consider the causes of ... running large corporations influenced the recent downturn of our economic situation, ...
... SOMERVILLE, N.J., Aug. 11 ETHICON, Inc., a Johnson ... Protective Disk with CHG (chlorhexidine gluconate) will include new ... surgeons, nurses and other healthcare providers to apply the product ... infections (CRBSIs). Distribution of BIOPATCH ((R)) with the enhanced ...
... SEA BRIGHT, N.J., Aug. 11 An insidious illness ... children. Its varied symptoms so closely mirror those of other ... matters worse, most doctors don,t know they could prevent the ... probiotics. , , Now Kathleen Kalaf, founder ...
Cached Medicine News:Health News:Prime Therapeutics 2009 Drug Trend Insights Shows Drug Spending Slows to Lowest Rate on Record 2Health News:Prime Therapeutics 2009 Drug Trend Insights Shows Drug Spending Slows to Lowest Rate on Record 3Health News:Ranbaxy Receives Final Approval To Market Sumatriptan Succinate Tablets 2Health News:Winner Medical Reports Third Quarter Fiscal 2009 Results 2Health News:Winner Medical Reports Third Quarter Fiscal 2009 Results 3Health News:Winner Medical Reports Third Quarter Fiscal 2009 Results 4Health News:Winner Medical Reports Third Quarter Fiscal 2009 Results 5Health News:Winner Medical Reports Third Quarter Fiscal 2009 Results 6Health News:Winner Medical Reports Third Quarter Fiscal 2009 Results 7Health News:Winner Medical Reports Third Quarter Fiscal 2009 Results 8Health News:Winner Medical Reports Third Quarter Fiscal 2009 Results 9Health News:Winner Medical Reports Third Quarter Fiscal 2009 Results 10Health News:Winner Medical Reports Third Quarter Fiscal 2009 Results 11Health News:Author Alison Stein Identifies Widespread Crisis in Personal Responsibility, Outlines Path to Solution in Reality 2Health News:ETHICON Introduces New Product Enhancement and Packaging for BIOPATCH(R) to Improve Ease of Application for Patients with Catheters 2Health News:Kathleen Kalaf's Atlantic Journey to Wellness Raises Awareness of Systemic Candida and Gains Sponsorship of Renowned Photographer Peter Simon 2Health News:Kathleen Kalaf's Atlantic Journey to Wellness Raises Awareness of Systemic Candida and Gains Sponsorship of Renowned Photographer Peter Simon 3
(Date:7/27/2015)... KONG , July 27, 2015 Bloomage ... 00963.HK) announces a strategic cooperation with the South Korean ... establish a joint venture Medybloom to develop and promote ... China . Medytox, the ... Korea, and is also the fourth company in the ...
(Date:7/27/2015)... 27, 2015  Cardica, Inc. (Nasdaq: CRDC ) today ... fourth quarter ended June 30, 2015, on Thursday, August 6, ... conference call at 4:30 p.m. Eastern Time to discuss the ... Conference Call Details To access the live ... Time via phone, please dial 877-703-6106 from the ...
(Date:7/27/2015)... Research and Markets ( http://www.researchandmarkets.com/research/7lz2fk/intraoperative ) has announced the ... (Intraoperative CT, Intraoperative MRI, Intraoperative Ultrasound) , by Geography ... 2019" report to their offering. ... $2.1 Billion by 2019 from $1.8 Billion in 2014, ... The intraoperative imaging market is divided ...
Breaking Medicine Technology:Bloomage (00963.HK) and Medytox Inc. set up a Joint Venture To Jointly Develop Botulinum Toxin Market in China 2Bloomage (00963.HK) and Medytox Inc. set up a Joint Venture To Jointly Develop Botulinum Toxin Market in China 3Cardica To Announce Fiscal 2015 Fourth Quarter Financial Results On Thursday, August 6, 2015 2Global Intraoperative Imaging (Intraoperative CT, Intraoperative MRI, Intraoperative Ultrasound) Market Forecasts & Trends 2015-2019 2
... Wash., Feb. 21, 2011 Royal Philips Electronics NV ... MSFT ) today announced the companies will collaborate ... to build and understand the complete clinical context of ... commitment to work together to connect technologies that will ...
... Medical, Inc. (Nasdaq: NXTM ), a leading ... recent independent study which reports that home hemodialysis with ... carbon footprint of therapy conducted with traditional in-center hemodialysis ... delivering superior clinical results is a core competency of ...
Cached Medicine Technology:Philips and Microsoft Collaborate to Streamline Radiology Workflow and Processes 2Philips and Microsoft Collaborate to Streamline Radiology Workflow and Processes 3Independent Study Reports 50% Smaller Carbon Footprint With NxStage System One™ vs. Standard In-Center Hemodialysis Machines 2Independent Study Reports 50% Smaller Carbon Footprint With NxStage System One™ vs. Standard In-Center Hemodialysis Machines 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: