Navigation Links
1 step closer to green chemistry and improved pharmaceuticals
Date:6/25/2008

Proteins are the workhorses of our cells. They help to digest our food, are at the core of our immune system, and literally shape our body from top to toe. Proteins also play an important role in biotechnology in the form of enzymes, which are important in the creation of anything from pharmaceuticals to bread, washing powder and much more. Their possibilities are virtually without limit.

To take advantage of their great potential, a detailed understanding of the three-dimensional shape of proteins is necessary. This is normally achieved through a complicated and expensive process in the laboratory. For years, researchers have tried to replace these experiments by computer simulations.

Now, two researchers at the Department of Biology at the University of Copenhagen, Assoc. professor Thomas Hamelryck and PhD-student Wouter Boomsma, have solved an important part of the problem of modeling the three dimensional shape of proteins. After 5 years of research, they have succeeded in developing a mathematical model that incorporates knowledge from physics, probability theory and geometry to describe the structure of proteins. This has given protein researchers a valuable new tool for the improved understanding of the shape and function of proteins.

"Each individual protein has its own unique chemical composition, consisting of 20 different amino acids in various different combinations. There are an endless number of such combinations, each giving rise to its own shape. We have developed a simple mathematical model that captures these different shapes. This means that it will become easier for industry and researchers to use proteins to achieve their goals. For example in the development of green chemistry, where dangerous chemicals are replaced with protein-based products, which are more environment friendly", says Thomas Hamelryck.

Thomas also points to the fact that their computer model can have a great impact on the pharmaceuti
'/>"/>

Contact: Thomas Hameryck
thamelryck@binf.ku.dk
452-396-0613
University of Copenhagen
Source:Eurekalert

Page: 1 2

Related medicine news :

1. UGA researchers 1 step closer to elusive cancer vaccine
2. Research Gets Closer to Origin of Parkinsons Disease
3. Study Gets Closer to Origins of Leukemia
4. Bug guts map brings scientists closer to understanding different bugs role in the body
5. UBs bioblower closer to protecting soldiers from biological attack
6. Closer Analysis Shows Consumer Groups Make Gains in Stem Cell Patent Challenges Against WARF; Appeal Still Planned Against Narrowed Claims
7. Governor Rendell Says Pennsylvania is One Step Closer to Providing Access to Health Care for Pennsylvanias Uninsured
8. Breast Cancer Lymph Node Biopsy May Need Closer Look
9. Thousands of volunteers needed to help bring cure for cancer closer
10. Family Healthcare Contributions Edge Closer to Full Months Salary, Says Aon Consulting
11. Accelerated Cure Project for Multiple Sclerosis is One Thousand Steps Closer to a Cure for MS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2014)... Researchers at the University of California, San Diego School ... those who have suffered a recent major loss are ... older adults. , The study is published in this ... Psychiatry . , Because compassionate behaviors are associated with ... findings offer insights into ways to improve the outcomes ...
(Date:4/17/2014)... biology team has created a new technology for ... could travel the body and selectively target cancer ... biological devices that monitor and modify human physiology ... However, no existing technology enabled bioengineers to build ... and respond in a customized fashion. , "The ...
(Date:4/17/2014)... The cause of neuronal death in Parkinson,s disease ... neurons may be mistaken for foreign invaders and killed ... way autoimmune diseases like type I diabetes, celiac disease, ... was published April 16, 2014, in Nature Communications ... idea in Parkinson,s disease; but if true, it could ...
(Date:4/17/2014)... EcoHealth Alliance, a nonprofit organization that focuses on conservation ... today examining the current state of knowledge of the ... improved global surveillance strategies to combat the emergence of ... in West Africa that has claimed the lives of ... According to the World Health Organization (WHO), the ...
(Date:4/17/2014)... April 2014) Population Council scientists and their partners have ... and can prevent the transmission of multiple sexually transmitted ... animals: HIV, herpes simplex virus 2 (HSV-2), and human ... data that the gel is effective against multiple strains ... the vagina against all three viruses of at least ...
Breaking Medicine News(10 mins):Health News:The ilk of human kindness 2Health News:Building 'smart' cell-based therapies 2Health News:Is Parkinson's an autoimmune disease? 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 3Health News:Animal study provides first evidence that gel can prevent multiple virus transmission in vagina/rectum 2
... surgery as infants for congenital heart disease (CHD) ... and hyperactivity, and,often require remedial services in school. ... problems, and our findings reinforce how important it,is ... said study leader Amanda J. Shillingford, M.D., a ...
... high in the antioxidant EGCG (epigallocatechin-3- gallate) which helps ... aged. Studies have suggested that the combination of green ... protection against certain types of cancers, including breast cancer. ... of Mississippi researchers now finds that consuming EGCG significantly ...
... in mammals (and this naturally includes humans) is an extraordinarily ... applies also to the formation in healthy eyes of elastic ... of the ciliary muscles, the lens can change its degree ... objects. As a result, a pin sharp image is created ...
... Care Services, WASHINGTON, April 7, 2008 As ... highlights the important role hospitals play,in supporting a strong ... and rank second as a source of private sector ... Hospital Association,s,(AHA) annual meeting in Washington. But hospitals and ...
... for Pre-Dilatation of Tight, ... That Require Best Crossability, HONG KONG, April ... received CE Mark approval for the Sapphire(TM) 1.25mm ... the interventional cardiology,community, Sapphire 1.25mm is a small-diameter ...
... Solutions, Inc.,(Accuro) (http://www.accurohealth.com ) today expanded its ... acquisition of TPMS, Inc. TPMS, based in,Framingham, Massachusetts, ... TPMS, corporate name will change to Accuro ... staffed with existing TPMS,personnel to continue to provide ...
Cached Medicine News:Health News:For Children With Heart Disease, a Risk of Attention and Behavior Problems 2Health News:Ingredient found in green tea significantly inhibits breast cancer growth in female mice 2Health News:When poor communication pokes you in the eye 2Health News:Analysis Highlights Economic Contribution of Hospitals to Communities 2Health News:OrbusNeich Receives CE Mark Approval for Sapphire(TM) 1.25MM PTCA Dilatation Catheter 2
(Date:1/15/2014)... NEW YORK , Jan. 15, 2014 ... research report is available in its catalogue: ... & Forecast – Worldwide Analysis ... Pump Market Analysis ...
(Date:1/15/2014)... 2014 Reportlinker.com announces that a new ... catalogue: Global Markets ... -- Focus on End Users ... A drug delivery system is ...
(Date:1/15/2014)... Ohio , Jan. 15, 2014  A novel wearable injector ... easy and painless for patients to self-inject prescription drugs in ... disorders, including cancer, blood diseases, autoimmune deficiencies, and genetic disorders.  ... to grow to $220B by 2018, according to analysts.   Many ...
Breaking Medicine Technology:Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 16Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 17Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on End Users 18Enable Injections Presents A New Class of Injectors for Drug Delivery at PEPTalk, Drug Delivery Partnership Meetings 2
... 2 Faced with rising technology costs and ... forced to make tough choices with scarce capital technology ... downright ugly. How do administrators choose which new technologies ... equipment can be reused? Keeping the right balance of ...
... , STAMFORD, Conn. , June 2 ... series of online instructional videos to help pain management advocates ... Social Media Guides provide an introduction to social media applications, ... setting up, using and maintaining these communication vehicles. Topics include ...
Cached Medicine Technology:ECRI Institute Reissues Cost-Saving Tips to Help Hospitals Make Capital Technology Purchases With Scarce Resources 2ECRI Institute Reissues Cost-Saving Tips to Help Hospitals Make Capital Technology Purchases With Scarce Resources 3ECRI Institute Reissues Cost-Saving Tips to Help Hospitals Make Capital Technology Purchases With Scarce Resources 4In the Face of PainĀ® Offers Social Media 101 for Pain Management Advocates 2
... is powerful, lightweight, easy ... soft, durable foam silicone ... covered by machine washable ... headband easily adjusts to ...
Solarc surgical headlight is durable, comfortable, lightweight and delivers the bright, white light expected from a xenon system, but at a fraction of the cost....
View Mex-3 is designed for out-patient surgery, hospital rounds and house calls....
It provides excellent illumination from an inexpensive platform and is mounted on the comfortable UltraLite headband....
Medicine Products: