Navigation Links
1 step closer to green chemistry and improved pharmaceuticals
Date:6/25/2008

Proteins are the workhorses of our cells. They help to digest our food, are at the core of our immune system, and literally shape our body from top to toe. Proteins also play an important role in biotechnology in the form of enzymes, which are important in the creation of anything from pharmaceuticals to bread, washing powder and much more. Their possibilities are virtually without limit.

To take advantage of their great potential, a detailed understanding of the three-dimensional shape of proteins is necessary. This is normally achieved through a complicated and expensive process in the laboratory. For years, researchers have tried to replace these experiments by computer simulations.

Now, two researchers at the Department of Biology at the University of Copenhagen, Assoc. professor Thomas Hamelryck and PhD-student Wouter Boomsma, have solved an important part of the problem of modeling the three dimensional shape of proteins. After 5 years of research, they have succeeded in developing a mathematical model that incorporates knowledge from physics, probability theory and geometry to describe the structure of proteins. This has given protein researchers a valuable new tool for the improved understanding of the shape and function of proteins.

"Each individual protein has its own unique chemical composition, consisting of 20 different amino acids in various different combinations. There are an endless number of such combinations, each giving rise to its own shape. We have developed a simple mathematical model that captures these different shapes. This means that it will become easier for industry and researchers to use proteins to achieve their goals. For example in the development of green chemistry, where dangerous chemicals are replaced with protein-based products, which are more environment friendly", says Thomas Hamelryck.

Thomas also points to the fact that their computer model can have a great impact on the pharmaceutical industry.

"Proteins and illness are highly related, and most pharmaceuticals are targeted at proteins in our body. As we increase our knowledge of these proteins, the chance of finding more efficient pharmaceuticals for illnesses such as cancer, diabetes and AIDS are greatly enhanced", Thomas continues.

The two researchers at the University of Copenhagen are currently collaborating closely with partners in the biotech industry to explore these possibilities.


'/>"/>

Contact: Thomas Hameryck
thamelryck@binf.ku.dk
452-396-0613
University of Copenhagen
Source:Eurekalert

Related medicine news :

1. UGA researchers 1 step closer to elusive cancer vaccine
2. Research Gets Closer to Origin of Parkinsons Disease
3. Study Gets Closer to Origins of Leukemia
4. Bug guts map brings scientists closer to understanding different bugs role in the body
5. UBs bioblower closer to protecting soldiers from biological attack
6. Closer Analysis Shows Consumer Groups Make Gains in Stem Cell Patent Challenges Against WARF; Appeal Still Planned Against Narrowed Claims
7. Governor Rendell Says Pennsylvania is One Step Closer to Providing Access to Health Care for Pennsylvanias Uninsured
8. Breast Cancer Lymph Node Biopsy May Need Closer Look
9. Thousands of volunteers needed to help bring cure for cancer closer
10. Family Healthcare Contributions Edge Closer to Full Months Salary, Says Aon Consulting
11. Accelerated Cure Project for Multiple Sclerosis is One Thousand Steps Closer to a Cure for MS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/20/2017)... ... 2017 , ... Uniform Advantage (UA), a multi-channel retailer of medical ... create tailored looks and athleisure-inspired outfits. UA Flex fabric is breathable, wrinkle resistant and ... With trendy looks hitting the medical community, UA Flex is for the medical professional ...
(Date:6/20/2017)... Dayton, OH (PRWEB) , ... June 20, 2017 ... ... medical staffing agency, recently became re-accredited by the Joint Commission, ... States. Joint Commission accreditation and certification is recognized nationwide as a symbol of ...
(Date:6/20/2017)... ... ... Uniworld Boutique River Cruise Collection recently gave cruisers a chance ... S.S. Joie de Vivre . What really sets this ship apart from the competition, ... small enough to dock directly in Paris. With The Cruise Web’s new infographic, you ...
(Date:6/20/2017)... ... June 20, 2017 , ... ... radio program, The Sharon Kleyne Hour Power of Water, Global Climate Change and ... to the world’s water crisis and how it affects the human eyes. ...
(Date:6/20/2017)... ... 20, 2017 , ... Bellus Medical, a leader in medical ... of Sales, a critical role to help spearhead business development, strategic sales plans ... McKenna is a seasoned business leader, joining Bellus Medical with more than 20 ...
Breaking Medicine News(10 mins):
(Date:6/12/2017)... Inc., a biotechnology company focused on the development of novel ... and Head of Virology Kristin Bedard has been invited to ... Beyond meeting sponsored by Life Science Washington.  This Symposium ... PDT at the Agora Conference Center in Seattle, ... joined by other leaders in infectious disease research and the ...
(Date:6/10/2017)... June 9, 2017  Shane K. Burchfield, DPM, is recognized by ... as a Podiatrist in Alabama . ... First Foot Care. He brings over 20 years of experience, as ... and healthcare, to his role. ... PC is pleased to welcome you to his practice," ...
(Date:6/9/2017)... , June 9, 2017 More than ... further effort to help spread lessons learned from clinical ... International Diabetes Federation (IDF) and Eli Lilly and Company ... the second phase of the Bringing Research in Diabetes ... their commitment to helping people with diabetes effectively manage ...
Breaking Medicine Technology: