Navigation Links
1 size may not fit all
Date:10/29/2007

INDIANAPOLIS While colonoscopy has become widely used for colorectal cancer screening, nearly two-thirds of screening colonoscopies show no cancer or pre-cancerous polyps. In an editorial in the October issue of the journal Gastroenterology, Thomas F. Imperiale, M.D., professor of medicine at the Indiana University School of Medicine and a Regenstrief Institute, Inc. research scientist, says that studies that can help determine who is at risk for colorectal cancer as well as who is not at risk and how to stratify risk for each group can help determine which screening test is best for each individual and will better serve both patients and the healthcare system.

If we knew more about risk factors for advanced neoplasia [cancer and advanced, precancerous polyps] and could effectively stratify risk, then screening and surveillance could be tailoredthat is, targeted to persons with high risk and away from those at low risk, who could either be examined with less invasive methods or perhaps not at all. Risk stratification and tailoring would improve the overall efficiency and effectiveness of colonoscopic screening and surveillance, Dr Imperiale wrote.

Dr. Imperiale is the lead investigator of the Risk Assessment in Colon Cancer Study, which is investigating whether using easily accessible factors such as age, family medical history, race, smoking history, body mass index, and other candidate factors can help determine who is and who is not at risk. That study also focuses on whether more sophisticated tools such as blood tests that look at genes, proteins or other markers of risk, would be effective.

Colonoscopy has become a common tool for screening partly by default, according to Dr. Imperiale.

Colonoscopy is the 500-pound gorilla. It has evolved into an acceptable screening test in part because many people believe that there are no other good options. To increase screening rates for colorectal cancers, we need to stress convenient and less invasive screening tests for those who are not at high risk for colorectal cancer and advanced, precancerous polyps, said Dr. Imperiale. First, however, we need a way to stratify risk among the nearly 90 percent of persons who are considered to be average-risk. Certainly, a hundred years from now - perhaps even 10 years from now screening colonoscopy will likely be looked upon as overkill, said Dr. Imperiale, who is a gastroenterologist and clinical epidemiologist.


'/>"/>

Contact: Cindy Fox Aisen
caisen@iupui.edu
317-274-7722
Indiana University
Source:Eurekalert

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2017)... ... January 20, 2017 , ... Doctor C LLC, a company based out ... trade show to continue the marketing and distribution of its product, The Right C. ... 400 percent better absorption than traditional vitamin C supplements. At the trade show, Doctor ...
(Date:1/20/2017)... ... , ... Michael and Betsy Brauser celebrated 5 years of Betsy’s participation in ... has been life-saving as she has been on the trial for more than ... with ovarian cancer in 2009. She underwent standard chemotherapy but a year later went ...
(Date:1/20/2017)... ... ... “Code Word: Chocolate Biscuit”: a biographical account following a man who went on to support ... author, Marlyn Ivey, born in Lynn Haven, Florida and at the age of 5, his ... of age, he joined the Navy and got married right out of boot camp. ...
(Date:1/20/2017)... ... ... “Knowledge is God’s Lighthouse”: a moving and colorful collection of prayers that reminds ... published author, Gene Gaapf, a retired truck driver, and a long-time writer, whose published ... high school and have many different titles,” Gaapf mentions about his different works. “I ...
(Date:1/19/2017)... ... 2017 , ... Next week after January 20th, the fear for many is ... circumvent health needs of over 30 million. Many interviews with Dr. Carol Francis at ... public servants were suppose to prioritize. Interviews provided below. , Among those ...
Breaking Medicine News(10 mins):
(Date:1/20/2017)... Research and Markets has announced the addition of ... report to their offering. ... This research service on the global pharmaceutical stability ... a snapshot of the key participants in the market. ... 2016 to 2020. The market is expected to grow at a ...
(Date:1/19/2017)... , Jan. 19, 2017 ... Summary GlobalData,s new report, "Germany Cataract Surgery ... on the Germany Cataract Surgery Devices market. The report ... units) and average prices (USD) within market segements - ... report also provides company shares and distribution shares data ...
(Date:1/19/2017)... Conference Call and Webcast to Follow Vanda Pharmaceuticals Inc. ... results for the fourth quarter of 2016 on Wednesday, February 15, ... ... PM ET on Wednesday, February 15, 2017, during which management will ... other corporate activities. To participate in the conference call, please dial ...
Breaking Medicine Technology: