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Respiratory Distress Treatment Studies Conflict
Date:2/12/2008

e lung with each breath, halved.

The new studies were aimed at settling a debate about how much PEEP should be applied at the end of each breath, enough to prevent lung collapse, but not so much as to damage lung tissue.

The basic point of the Canadian study to Hudson was tidal volume. "To me, what it says is that probably the most important thing about lung protection is making sure the tidal volume is low," he said. "That allows you to use as high a level of PEEP as you want."

Angus had a quite different view, saying that individually calculated higher PEEP levels were the decisive factors. "It's pretty hard to argue that we should continue to do what we have been doing," Angus said.

More information

For more on ARDS, head to the U.S. National Library of Medicine.



SOURCES: Derek C. Angus, M.D., chairman, department of critical care medicine, University of Pittsburgh; Leonard C. Hudson, M.D., head, division of pulmonary and critical medicine, University of Washington, Seattle; Gordon H. Guyatt, M.D., professor, medicine, McMaster University, Toronto; Feb. 13, 2008, Journal of the American Medical Association


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