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Parkinson's Transplant Mystery Solved, Researchers Say
Date:6/30/2010

patients is fascinating," Okun said. "Caution, however, should be exercised in interpreting these results. No conclusion can be drawn concerning long-term treatment efficacy, and these results cannot be applied in patients who did not receive fetal cell transplants."

The most common treatment for Parkinson's is levodopa, which is converted into dopamine in the brain. Over time, people who take levodopa can also develop dyskinesias, but perhaps because of a different mechanism, Politis said.

Previous research has hinted at the role of serotonin in dyskinesias for other Parkinson's patients.

More information

The National Parkinson Foundation has more on the disease.

SOURCES: Marios Politis, Ph.D., M.D, clinical science, Imperial College London; Michael S. Okun, M.D., national medical director, National Parkinson Foundation; June 30, 2010, Science Translational Medicine


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