Navigation Links
Parkinson's Transplant Mystery Solved, Researchers Say
Date:6/30/2010

ded no medication for Parkinson's -- not everyone improved, Politis said.

And over time, the majority of transplanted patients suffered dyskinesias, leading ethics commissions around the world to end human trials in the 1990s, he said.

In the new study, using brain imaging, Politis and his colleagues found that the dopamine neurons that decay in Parkinson's disease were restored and functioning in the two patients. But they also found abnormal levels of serotonin neurons within the transplanted tissue.

The serotonin neurons were releasing dopamine, which, when coming from the wrong source, caused the jerking movements.

When patients were given a serotonin receptor agonist, a drug that prevented the serotonin neurons from firing, the involuntary movements ceased.

"Both patients responded by a sudden and almost complete resolution of the troublesome abnormal movements, suggesting that the excess serotonergic neurons had in fact been pumping out dopamine, causing the dyskinesias," Politis said.

It's possible that removing serotonin cells during the preparation of transplanted tissue in future trials will prevent side effects from developing, he added.

"We believe the first priority is to make the whole procedure more safe," Politis said. "We need to establish patients won't have anything worse happening to them after the surgery. And this study addresses that."

European and North American researchers plan a new round of human trials with fetal cells in Parkinson's disease in 2012, Politis said.

Dr. Michael S. Okun, national medical director for the National Parkinson Foundation, said the study "offers some potentially important insights into the role of serotonin in off-medication dyskinesias that may be encountered following Parkinson's disease fetal cell grafting."

"The notion that a simple drug acting on the serotonin system, buspirone, proved useful in short, four-hour testing performed in two
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

1

GOOD

Page: 1 2 3

Related medicine news :

1. Higher cancer rates found in liver transplant patients receiving cyclosporine for immunosuppression
2. Israel Penn Registry marks 3,000 consults for transplant care providers
3. The experience of arterial reconstruction in adult-to-adult living donor liver transplantation
4. Longer Antiviral Therapy Reduces Lung Transplant Complications
5. Immune system helps transplanted stem cells navigate in central nervous system
6. Lack of private insurance contribute to higher deaths among black heart transplant patients
7. Color-coded tracking method helps scientists analyze outcomes of newly transplanted tissue
8. Shortage of Transplant Organs Spurs Proposals But No Solution
9. Gene pattern may identify kidney transplant recipients who dont need lifelong anti-rejection drugs
10. Gene pattern may identify kidney transplant recipients who dont need life-long anti-rejection drugs
11. African-Americans and women are less likely to undergo bone marrow transplantation
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
 Parkinson's Transplant Mystery Solved, Researchers Say 
(Date:6/20/2013)... The rates of obesity and weight-related diseases ... for the answer to fast weight loss. Doctors, scientists ... in addressing initial fat loss, but fail to provide ... in the future. Diet Doc developed these ... assist patients in achieving fast weight loss, they also ...
(Date:6/20/2013)... Indianapolis, IN (PRWEB) June 20, 2013 ... Many employers are concerned that this cost percentage will ... burden of caring for both aging parents and adult ... claims management can either provide workers a road block, ... , United Benefit Advisors (UBA), in ...
(Date:6/20/2013)... June 20, 2013 During a June ... director of the Maryland Health Benefit Exchange confirmed the ... that many in the industry consider,” writes panel moderator ... “as mythical as unicorns and leprechauns.” , “We ... the Federal Data Services Hub live,” Rebecca Pearce told ...
(Date:6/20/2013)... (PRWEB) June 20, 2013 Dr. Ramtin ... in New Jersey and NYC and ... practice since 1997, his philosophy is to provide individualized care ... facelifts, eyelid-lifts, and laser-lifts. The surgeon is partnering with the ... as Bain & Co for its specialized needs. , "We ...
(Date:6/20/2013)... (PRWEB) June 20, 2013 Volume based ... to dramatically reduce the retail pricing of both it's ... meal replacement products. , Premier Natural Health’s whey ... natural food sources and are formulated to help maintain ... calorie intake and slow the aging process. , ...
Breaking Medicine News(10 mins):Health News:hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offer Patients Fast Weight Loss With New hCG Diets, Easily Maintaining Weight In the Future With Healthy Eating 2Health News:hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offer Patients Fast Weight Loss With New hCG Diets, Easily Maintaining Weight In the Future With Healthy Eating 3Health News:United Benefit Advisors and Symetra Host Absence Management Webinar 2Health News:United Benefit Advisors and Symetra Host Absence Management Webinar 3Health News:Federal Data Services Hub Does Exist, AISHealth.com Blog Post Reports 2Health News:Celebrity Plastic Surgeon Dr. Kassir Teams Up With X Factor Selling Systems to Enhance Patient Experience 2Health News:Premier Natural Health, a Leading Provider of Natural Food Products and Herbal Solutions, Reduces Prices On Its Popular Whey Protein Product 2Health News:Premier Natural Health, a Leading Provider of Natural Food Products and Herbal Solutions, Reduces Prices On Its Popular Whey Protein Product 3
... 2011 Los Angeles Biomedical Research Institute at Harbor-UCLA ... biotechnology firm, have entered into a two-year research agreement ... "Cell Sheet Engineering," LA BioMed President and CEO David ... working to accelerate the pace of discovery and development ...
... a study published in Blood , the Journal ... relationship between pulmonary arterial hypertension (PAH)exceedingly high blood pressure ... the lungsand abnormalities of the blood-forming cells in the ... which was conducted by a team of researchers at ...
... , MONDAY, Feb. 28 (HealthDay News) -- In ... Pediatrics (AAP) said it supports legislation that would bar children ... Stricter regulations are currently being mulled by the U.S. Food ... already advocated barring minors from using tanning beds, or at ...
... could have cardiovascular benefits according to new research by Ryan ... in the US. Their study, looking at the effect of ... found that those participants who slept for at least 45 ... psychological stress than those who did not sleep. The work ...
... NY - A brain imaging study at the U.S. Department ... between ordinary obese subjects and those who compulsively overeat, or ... mere sight or smell of favorite foods triggers a spike ... motivation. The findings - published online on February 24, 2011, ...
... FL (February 28, 2011) The University of ... School of Medicine were recently awarded a Howard ... an innovative competency-based premedical curriculum in response to ... Medical Institute "Scientific Foundations for Future Physicians (SFFP)" ...
Cached Medicine News:Health News:LA BioMed and CellSeed to launch joint research project on regenerative medicine technology 2Health News:Study finds close linkage between a rare, deadly lung condition and blood cell abnormalities 2Health News:Pediatricians' Group Backs Ban on Tanning Booth Use by Minors 2Health News:Blood pressure management: Sleep on it 2Health News:Binge eaters' dopamine levels spike at sight, smell of food 2Health News:Binge eaters' dopamine levels spike at sight, smell of food 3Health News:University of Miami awarded Howard Hughes Medical Institute experiment grant 2
(Date:6/19/2013)... -- Dr. Davis Lee , CMIO for PIH ... the 2013 AMDIS Award, a prestigious recognition saluting excellence ... "On behalf of Allscripts, I,d like to congratulate ... continuous efforts to improve patient care and population health," ... Executive Officer of Allscripts. "We are committed to our ...
(Date:6/19/2013)... WASHINGTON , June 19, 2013 The American ... provider from Maryland , announced today the ... in Washington, D.C. , asking that the ... (CBP) for durable medical equipment (DME) be stopped because of ... of Health and Human Services (HHS) Secretary Kathleen ...
(Date:6/19/2013)... Calif. , June 19, 2013 Amgen is ... the United States , Canada ... year,s recipients of the Amgen Award for Science Teaching Excellence ... teachers at the kindergarten through 12th grade level who have ... science education. With a long-standing commitment to science ...
Breaking Medicine Technology:Allscripts Congratulates Dr. Davis Lee, Winner of the 2013 Association of Medical Directors of Information Systems (AMDIS) Award 2Allscripts Congratulates Dr. Davis Lee, Winner of the 2013 Association of Medical Directors of Information Systems (AMDIS) Award 3Allscripts Congratulates Dr. Davis Lee, Winner of the 2013 Association of Medical Directors of Information Systems (AMDIS) Award 4Allscripts Congratulates Dr. Davis Lee, Winner of the 2013 Association of Medical Directors of Information Systems (AMDIS) Award 5AAHomecare and Maryland DME Provider Take Medicare Agency to Court Over Competitive Bidding Program 2AAHomecare and Maryland DME Provider Take Medicare Agency to Court Over Competitive Bidding Program 3AAHomecare and Maryland DME Provider Take Medicare Agency to Court Over Competitive Bidding Program 4AAHomecare and Maryland DME Provider Take Medicare Agency to Court Over Competitive Bidding Program 5Amgen Award For Science Teaching Excellence Honors Outstanding Teachers 2Amgen Award For Science Teaching Excellence Honors Outstanding Teachers 3
... , LOS ANGELES , Jan. ... on Tuesday, 4 Survival To Go , an emergency preparedness company ... Alonzo Mourning to help provide aid to the impoverished nation via ... the end of February, 4 Survival To Go will donate 20% ...
... 7 The Providence Service Corporation (Nasdaq: PRSC ... is scheduled to present an overview of the Company,s operations at ... January 11, 2010 at The Grand Hyatt Hotel in New York ... , On Thursday, January 14, 2010, Mr. McCusker will also ...
Cached Medicine Technology:Help the Haitian Community and Prepare for an Unexpected Disaster 2Help the Haitian Community and Prepare for an Unexpected Disaster 3Help the Haitian Community and Prepare for an Unexpected Disaster 4Providence Service Corporation to Present at the Sidoti & Company, LLC Micro Cap Conference on Monday, January 11th and at the CJS Securities 'New Ideas for the New Year' Conference on Thursday, January 14th 2
For use in implant arthroplasty associated with comminuted fractures, or rheumatoid, degenerative or post-traumatic disease of the radial head. Designed for higher demand patients requiring superior ...
For connection to the bipolar output of electrosurgical generators....
This legless table has adjustable height and round post. Pad sold separately....
This legless table has adjustable height and blade post. Includes standard 2" (5 cm) pad....
Medicine Products: