Navigation Links
New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes
Date:11/21/2008

ay.
  • rat fertility studies with oral gavage doses of 125, 250, and 1000mg/kg, males were treated for 4 weeks prior to mating, during mating, up to scheduled termination (approximately 8 weeks total) and females were treated 2 weeks prior to mating through gestation day 7. No adverse effect on fertility was observed at 125mg/kg (approximately 12 times human exposure at the MRHD of 100mg/day based on AUC comparisons). At higher doses, nondose-related increased resorptions in females were observed (approximately 25 and 100 times human exposure at the MRHD based on AUC comparison).

  • CLINICAL STUDIES

There were approximately 3800 patients with type 2 diabetes randomized in six double-blind, placebo-controlled clinical safety and efficacy studies conducted to evaluate the effects of sitagliptin on glycemic control. The ethnic/racial distribution in these studies was approximately 60% white, 20% Hispanic, 8% Asian, 6% black, and 6% other groups. Patients had an overall mean age of approximately 55 years (range 18 to 87 years). In addition, an active (glipizide)-controlled study of 52-weeks duration was conducted in 1172 patients with type 2 diabetes who had inadequate glycemic control on metformin.


    Source: PRWeb
    Copyright©2008 Vocus, Inc.
    All rights reserved  

    Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33

    Related medicine news :

    1. STAAR Surgical Forms Team of Leading Ophthalmic Surgeons to Study the Use of Collamer(R) Material for Accommodating Intraocular Lenses
    2. Landmark study defines benefits of early HIV testing and treatment for infected infants
    3. Study identifies causes of bone loss in breast cancer survivors
    4. New Study by BioTrends Highlights Practice Management Shifts Among Canadian Nephrologists
    5. Study Suggests Need for More Aggressive Outpatient Monitoring of Patients Hearts When Cause of Stroke is Unclear
    6. Rutgers researchers study cites media violence as critical risk factor for aggression
    7. Brigham and Womens Researchers Partner with Vocantas to use CallAssure in Clinical Research Study
    8. Analyst Available to Comment on New JUPITER Study That Shows AstraZenecas Crestor Significantly Reduces CV Risk
    9. New Study Finds CO2 Ablative Fractional Resurfacing Safe And Effective For Deep Acne Scarring
    10. Study investigates Gore-tex-type device to stop strokes and mini-strokes
    11. The smart way to study
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    Related Image:
     New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes 
    (Date:5/1/2015)... Islands, BWI (PRWEB) May 02, 2015 ... It is http://www.thevenetiangracebay.com , and it is ... incorporates the stunning white and attractive turquoise hues of ... of Google, sixty seven percent of leisure travelers used ... showed that smartphones were used in the planning and ...
    (Date:5/1/2015)... 01, 2015 Royal River Natural Foods, ... reports on a new study that found two natural ... and improved physical function as well as standard drug ... of the knee. , The report is part of ... Well Being® ,” which Royal River Natural Foods publishes ...
    (Date:5/1/2015)... Washington, DC (PRWEB) May 01, 2015 It’s ... Senate and House introducing proposals to expand federal support for ... 22 years that ATA has been working with Congress,” said ... “These actions signify how the nation is poised to embrace ... This is one more step in fulfilling ATA’s mission to ...
    (Date:5/1/2015)... Yorba Linda, CA (PRWEB) May 01, 2015 ... of our genetic makeup and the interplay of genes ... Keeping up with developments can be daunting. , LabRoots, ... sciences and clinical diagnostics professionals, will soon host its ... Genomics. , At BioConference Live Genetics and Genomics ...
    (Date:5/1/2015)... Denver, Colorado (PRWEB) May 01, 2015 ... United States approaches its 18-month anniversary, many people in ... what’s been achieved. , According the latest annual report ... industry expanded 74 percent in 2014, and reached nearly ... Meanwhile, America’s decades-long love affair with cannabis, combined with ...
    Breaking Medicine News(10 mins):Health News:Turks and Caicos Resort, The Venetian on Grace Bay, Launches New Web Presence 2Health News:New Study Finds Nutrients Ease Arthritis Pain, Retailer Reports 2Health News:ATA: Congress Floods the Halls with Telemedicine Proposals 2Health News:Recent Advances in Genetics and Genomics: A BioConference Live 2015 Virtual Event 2Health News:Recent Advances in Genetics and Genomics: A BioConference Live 2015 Virtual Event 3Health News:Colorado cannabis dispensary owner credits employees for successful “420” retail sales figures 2Health News:Colorado cannabis dispensary owner credits employees for successful “420” retail sales figures 3
    ... Arrangement with ... ... ASPV ; TSX: ASV) today announced that meeting materials,regarding a special ... Group (SWX: GALN) have been,mailed to Aspreva shareholders and optionholders of ...
    ... StructuRad to Demonstrate Innovative Radiology Reporting Solutions, ... announces,MacroLive, a macro reporting service, at RSNA 2007 ... INFINITT and RamSoft, will offer,this service as an ... is a subscription service that allows a radiologist ...
    ... to Finally Announce Second-Line AIDS Treatment Provision on World AIDS ... ... Nov. 22 Bowing to an,increasing need for more effective AIDS treatments ... activists,India,s National AIDS Control Organization (NACO) and Health Minister A.,Ramadoss will announce ...
    ... Toronto, Canada People with a devastating brain injury ... may still be able to understand other peoples feelings ... Rotman Research Institute at the Baycrest Centre for Aging ... Faculty of Health. , The study, published in the ...
    ... priorities that will impact on the future treatment of breast ... the disease. Research published in the online open access ... issues highlighted as top priorities. , A team led ... Marsden NHS Foundation Trust, based in London and Surrey, together ...
    ... on hearts, researchers say , , WEDNESDAY, Nov. 21 (HealthDay ... together to boost death risks from heart disease and ... -- which brings more heat and more ozone -- ... of cardiovascular events. , "Temperature and ozone are strong ...
    Cached Medicine News:Health News:Aspreva Sends Materials for Special Meeting to be Held December 17 2Health News:Aspreva Sends Materials for Special Meeting to be Held December 17 3Health News:Aspreva Sends Materials for Special Meeting to be Held December 17 4Health News:StructuRad Launches MacroLive(TM) with INFINITT and RamSoft at RSNA 2007 2Health News:StructuRad Launches MacroLive(TM) with INFINITT and RamSoft at RSNA 2007 3Health News:NACO Bows to Activists' Pressure on AIDS Treatment in India, Says AHF 2Health News:NACO Bows to Activists' Pressure on AIDS Treatment in India, Says AHF 3Health News:People with rare type of memory loss still sensitive to others, study shows 2Health News:People with rare type of memory loss still sensitive to others, study shows 3Health News:Found in translation: Prioritizing research questions in breast cancer 2Health News:Global Warming May Trigger Rise in Heart Deaths 2Health News:Global Warming May Trigger Rise in Heart Deaths 3
    (Date:5/1/2015)... N.J. , May 1, 2015 /PRNewswire/ ... has expanded its current therapeutic focus beyond ... other serious psychiatric disorders. Braeburn has acquired ... (or second-generation) antipsychotic risperidone for treatment of ... acquisition Braeburn acquires global rights to other ...
    (Date:5/1/2015)... 2015 Semler Scientific, Inc. (Nasdaq: SMLR ... manufactures and markets products that assist healthcare providers in ... results for the first quarter ended March 31, 2015. ... Semler reported continued progress with year over year growth ... of 14%," said Doug Murphy-Chutorian , M.D., chief ...
    (Date:4/30/2015)... , April 30, 2015 /PRNewswire/ - Pivotal ... pharmaceutical company with a focus on Omega-3 therapies ... its operational highlights and financial results for the ... amounts referenced herein are in Canadian dollars unless ... have been significant, with the right strategic partners ...
    Breaking Medicine Technology:Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 2Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 3Braeburn Pharmaceuticals expands pipeline to include two schizophrenia treatments 4Semler Reports First Quarter 2015 Financial Results 2Semler Reports First Quarter 2015 Financial Results 3Semler Reports First Quarter 2015 Financial Results 4Semler Reports First Quarter 2015 Financial Results 5Pivotal Therapeutics Announces 2014 Financial Results 2Pivotal Therapeutics Announces 2014 Financial Results 3Pivotal Therapeutics Announces 2014 Financial Results 4Pivotal Therapeutics Announces 2014 Financial Results 5Pivotal Therapeutics Announces 2014 Financial Results 6
    ... NEW YORK, Jan. 25, 2011 Reportlinker.com announces ... in its catalogue: Future Technological ... Market through 2018 http://www.reportlinker.com/p0365289/Future-Technological-Breakthroughs-And-Their-Impact-on-the-US-Diagnostics-Market-through-2018.html ... will be marked by significant technological developments in ...
    ... Angelini Labopharm, LLC, today confirmed Mary ... Senior Vice President, Sales and Marketing for Labopharm Inc. ... USA, Inc., Ms. Heino,s primary focus will be to ... of OLEPTRO™, as well as to explore opportunities for ...
    Cached Medicine Technology:Reportlinker Adds Future Technological Breakthroughs and Their Impact on the US Diagnostics Market Through 2018 2Angelini Labopharm Confirms Appointment of Mary Anne Heino as President 2Angelini Labopharm Confirms Appointment of Mary Anne Heino as President 3
    ... with its new stand F19 contains three high ... one hand to homogenously move the arms and ... solid and stable microscope. The Leica M844 F19 ... on the same small footprint and holds the ...
    ... is a high-throughput immunoassay system built around ... 2000 with the important addition of Logic ... to be designed for optimal performance with ... for critical assays such as the cardiac ...
    ... Detection Of Serum C-Peptide ... Measurement:, Evaluating patients ... Assisting in the classification ... Differentiating insulin dependent patients ...
    Measles IgG ELISA test system is designed for the qualitative detection of IgG antibodies to Measles (Rubeola) virus in human serum, and is for in vitro diagnostic use....
    Medicine Products: