Navigation Links
New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes
Date:11/21/2008

ay.
  • rat fertility studies with oral gavage doses of 125, 250, and 1000mg/kg, males were treated for 4 weeks prior to mating, during mating, up to scheduled termination (approximately 8 weeks total) and females were treated 2 weeks prior to mating through gestation day 7. No adverse effect on fertility was observed at 125mg/kg (approximately 12 times human exposure at the MRHD of 100mg/day based on AUC comparisons). At higher doses, nondose-related increased resorptions in females were observed (approximately 25 and 100 times human exposure at the MRHD based on AUC comparison).

  • CLINICAL STUDIES

There were approximately 3800 patients with type 2 diabetes randomized in six double-blind, placebo-controlled clinical safety and efficacy studies conducted to evaluate the effects of sitagliptin on glycemic control. The ethnic/racial distribution in these studies was approximately 60% white, 20% Hispanic, 8% Asian, 6% black, and 6% other groups. Patients had an overall mean age of approximately 55 years (range 18 to 87 years). In addition, an active (glipizide)-controlled study of 52-weeks duration was conducted in 1172 patients with type 2 diabetes who had inadequate glycemic control on metformin.


    Source: PRWeb
    Copyright©2008 Vocus, Inc.
    All rights reserved  

    Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33

    Related medicine news :

    1. STAAR Surgical Forms Team of Leading Ophthalmic Surgeons to Study the Use of Collamer(R) Material for Accommodating Intraocular Lenses
    2. Landmark study defines benefits of early HIV testing and treatment for infected infants
    3. Study identifies causes of bone loss in breast cancer survivors
    4. New Study by BioTrends Highlights Practice Management Shifts Among Canadian Nephrologists
    5. Study Suggests Need for More Aggressive Outpatient Monitoring of Patients Hearts When Cause of Stroke is Unclear
    6. Rutgers researchers study cites media violence as critical risk factor for aggression
    7. Brigham and Womens Researchers Partner with Vocantas to use CallAssure in Clinical Research Study
    8. Analyst Available to Comment on New JUPITER Study That Shows AstraZenecas Crestor Significantly Reduces CV Risk
    9. New Study Finds CO2 Ablative Fractional Resurfacing Safe And Effective For Deep Acne Scarring
    10. Study investigates Gore-tex-type device to stop strokes and mini-strokes
    11. The smart way to study
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    Related Image:
     New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes 
    (Date:12/26/2014)... It is said that nothing makes a lady feel ... wedding dress supplier, shows its new selection of navy ... , UWDress.com’s navy cocktail gowns are the cornerstones of ... fashion styles. Simple dresses in bright neon colors can be ... specially designed for those who want to shine among the ...
    (Date:12/26/2014)... Aliso Viejo, California (PRWEB) December 26, 2014 ... have announced the TransPack Volume 5 Plugin for Final Cut ... to manipulate a hard light tool to pull off an ... Studios. “When users get their hands on TransPack Volume 5, ... TransPack Volume 5 is a set of over 50 Final ...
    (Date:12/26/2014)... DW-InductionHeating.com (DaWei Induction Heating Co.) is a comprehensive ... and marketing of a series of induction heating equipment. ... series of induction brazing equipments . , According ... brazing refers to the joining of two or ... The manager says that there are fundamental differences in ...
    (Date:12/25/2014)... December 26, 2014 The ... combines beauty, strength and durability. Today, the business ... which is valid until Jan. 30, 2015. , ... of traditional hardwood. BambooFlooringChina.com is a well-known brand ... consumers worldwide to find a reliable bamboo flooring ...
    (Date:12/25/2014)... months the trends for evening dresses shift and ... of the hottest styles in the next few months.” The ... 26 A-line sweetheart evening dresses, and announces the availability of ... trying our best to help a lady to show off ... prices, we provide discounted delivery costs to our customers worldwide. ...
    Breaking Medicine News(10 mins):Health News:UWDress.com Shows Its New Navy Cocktail Dresses For 2015 2Health News:Today a new plugin was announced from Pixel Film Studios, TransPack Volume 5 for Final Cut Pro X 2Health News:Induction Brazing Equipment Series From DaWei Induction Heating Co., A Reliable Supplier Of Induction Heating Equipment 2Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2
    ... IL Earlier school start times are associated with increased ... will be presented Wednesday, June 9, 2010, in San Antonio, ... Associated Professional Sleep Societies LLC. Results indicate that in ... in Virginia Beach, Va., where high school classes began at ...
    ... called tasquinimod slowed the rate of disease progression in ... to experts at Johns Hopkins, Roswell Park Cancer Institute ... drug that squeezes off blood supply to prostate tumors ... these vast networks of blood vessels to supply nutrients. ...
    ... common, they are only partially effective without standardized, ... to a study conducted by University of Cincinnati ... UC associate professor of emergency medicine Stewart Wright, ... treatment of pneumonia to create clinical guidelines for ...
    ... get from restaurants, cafeterias and other food-service providers? A new ... to place video cameras in commercial kitchens to see how ... risky practices happen more often than previously thought. "Meals ... 70 percent of food poisoning outbreaks, making them a vital ...
    ... IL Regulations that limit the number of hours ... to maximize workers, sleep opportunity and minimize the risk ... will be presented Tuesday, June 8, 2010, in San ... of the Associated Professional Sleep Societies LLC. Results ...
    ... A community-based health promotion program delivered by over 500 ... seniors, Canadian Stroke Network researcher Dr. Janusz Kaczorowski told ... the Cardiovascular Health Awareness Program (CHAP), family physicians in ... over to attend risk assessment sessions held at local ...
    Cached Medicine News:Health News:Teen automobile crash rates are higher when school starts earlier 2Health News:Drug that restricts blood supply to prostate tumors delays disease progression 2Health News:'Knowledge translation' keeps treatment current 2Health News:Video study finds risky food-safety behavior more common than thought 2Health News:Video study finds risky food-safety behavior more common than thought 3Health News:The best and worst work schedules: Shift start times can impact sleep and alertness 2Health News:The best and worst work schedules: Shift start times can impact sleep and alertness 3Health News:A good CHAP reduces rates of heart disease and stroke in communities. 2
    (Date:12/24/2014)... 2014  The International Trade Commission (ITC) issued its final ... Medical. In a notice issued on December 23, the ITC ... on its humidifier was invalid. BMC President, ... are very excited with the ITC,s decision in this case. ... taken since the very beginning on the key patents in ...
    (Date:12/24/2014)... Mich. , Dec. 24, 2014  Diplomat Pharmacy, ... independent specialty pharmacy, is proud to announce Jennifer ... quality at Diplomat, will take office as the president ... The formal induction ceremony will take place Feb. 28, ... will be held at the Renaissance Center in ...
    (Date:12/24/2014)... YORK and LONDON , ... global orthopedic industry are expected to grow at an ... in terms of value and volume. Hip, knee and ... developed world while in emerging economies they have a ... rates are challenging the use of composites. Non-metallic orthopedic ...
    Breaking Medicine Technology:ITC Final Decision Goes Against ResMed (RMD) Monumental Win for 3B/BMC 2Diplomat's senior director of education and quality to be inducted as 2015 president of the Michigan Pharmacists Association 2Diplomat's senior director of education and quality to be inducted as 2015 president of the Michigan Pharmacists Association 3Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3
    ... Inc., the maker of OneTouch® Brand Blood Glucose Monitoring Systems, ... Rite Track Diabetes Tour . Beginning on November ... will travel to various Rite Aid pharmacies in eight cities ... A1c testing, educational materials and free product samples and offers ...
    ... Holdings, Inc. (NYSE and SIX: ZMH), a global leader ... in the 2011 Credit Suisse Annual Health Care Conference ... Arizona on November 9, 2011, at 8:00 a.m. local ... presentation can be accessed via Zimmer,s Investor Relations website ...
    Cached Medicine Technology:Celebrity Chef Sam Talbot Gets on Board for Diabetes Testing 2Celebrity Chef Sam Talbot Gets on Board for Diabetes Testing 3Celebrity Chef Sam Talbot Gets on Board for Diabetes Testing 4Zimmer Holdings to Present at 2011 Credit Suisse Annual Health Care Conference 2
    Integrate RFID and bar code technology with the new DR1000 Dual RFID/Bar Code Reader by Precision Dynamics Corporation (PDC). It provides an easy migration from bar codes to RFID tags for healthcare ...
    ... The Health Trax System ... (RTLS), long range active RFID, ... in a single intergrated infrastructure. ... valuble assets and people in ...
    ... is part of the Kisses mother/infant ... The Kisses tag is given to ... been bonded with the Hugs tag ... tags remain electronically bonded throughout the ...
    The PDC Smart® Key Fob can be programmed on demand using a 13.56 MHz RFID reader/writer and is ideal for long-term use applications such as electronic access control or loyalty programs....
    Medicine Products: