Navigation Links
New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes
Date:11/21/2008

glucose load or a meal.
  • a two-day study in healthy subjects, sitagliptin alone increased active GLP-1 concentrations, whereas metformin alone increased active and total GLP-1 concentrations to similar extents. Co-administration of sitagliptin and metformin had an additive effect on active GLP-1 concentrations. Sitagliptin, but not metformin, increased active GIP concentrations. It is unclear how these findings relate to changes in glycemic control in patients with type 2 diabetes.

  • studies with healthy subjects, JANUVIA did not lower blood glucose or cause hypoglycemia.

Cardiac Electrophysiology

  • a randomized, placebo-controlled crossover study, 79 healthy subjects were administered a single oral dose of JANUVIA 100mg, JANUVIA 800mg (8 times the recommended dose), and placebo. At the recommended dose of 100mg, there was no effect on the QTc interval obtained at the peak plasma concentration, or at any other time during the study. Following the 800mg dose, the maximum increase in the placebo-corrected mean change in QTc from baseline was observed at 3 hours postdose and was 8.0msec. This increase is not considered to be clinically significant. At the 800mg dose, peak sitagliptin plasma concentrations were approximately 11 times higher than the peak concentrations following a 100mg dose.

  • patients with type 2 diabetes administered JANUVIA 100mg (N=81) or JANUVIA 200mg (N=63) daily, there were no meaningful changes in QTc interval based on ECG data obtained
    '/>"/>

Source: PRWeb
Copyright©2008 Vocus, Inc.
All rights reserved  

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33

Related medicine news :

1. STAAR Surgical Forms Team of Leading Ophthalmic Surgeons to Study the Use of Collamer(R) Material for Accommodating Intraocular Lenses
2. Landmark study defines benefits of early HIV testing and treatment for infected infants
3. Study identifies causes of bone loss in breast cancer survivors
4. New Study by BioTrends Highlights Practice Management Shifts Among Canadian Nephrologists
5. Study Suggests Need for More Aggressive Outpatient Monitoring of Patients Hearts When Cause of Stroke is Unclear
6. Rutgers researchers study cites media violence as critical risk factor for aggression
7. Brigham and Womens Researchers Partner with Vocantas to use CallAssure in Clinical Research Study
8. Analyst Available to Comment on New JUPITER Study That Shows AstraZenecas Crestor Significantly Reduces CV Risk
9. New Study Finds CO2 Ablative Fractional Resurfacing Safe And Effective For Deep Acne Scarring
10. Study investigates Gore-tex-type device to stop strokes and mini-strokes
11. The smart way to study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
 New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes 
(Date:7/23/2014)... 23, 2014 Thousands of DePuy Pinnacle ... in a federal multidistrict litigation underway in U.S. District ... According to an Order dated July 18th, U.S. District ... payment of a $1,000 fee for the preservation and ... Among other things, the Order noted that there is ...
(Date:7/23/2014)... RIVERSIDE, Calif. Fragile X syndrome ( FXS ) ... behaviors, and other behaviors on the autistic spectrum, as ... inherited cause of mental impairment and the most common ... University of California, Riverside have published a study ... behaviors in FXS. Appearing online today (July 23) in ...
(Date:7/23/2014)... The voice on the recording was low and calm as the ... infected with the human immunodeficiency virus (HIV) that causes AIDS: “My ... know I was on the floor flat on my face boohooing, ... the recording ended less than 10 minutes later. “Don’t feel like ... it is just God setting you up for something greater,” the ...
(Date:7/23/2014)... Roanoke, Virginia (PRWEB) July 23, 2014 ... Levelers headquarters in Roanoke, Virginia on Friday, July 18. ... Virginia Amateur Sports Subway Commonwealth Games, an Olympic-style event ... in its first year as a premier sponsor of ... lifestyles to people of all ages and all activity ...
(Date:7/23/2014)... (HealthDay News) --,Jealousy may not be the sole domain ... downright possessive when it comes to the love of ... what was actually a stuffed dog, the real puppies ... stuffed dog aside, report researchers from the University of ... surfaced when owners were attending to the stuffed dog ...
Breaking Medicine News(10 mins):Health News:DePuy Pinnacle Hip Lawsuits Move Forward, as Federal Judge Denies Hospital Bid for $1000 Explant Fee, Bernstein Liebhard LLP Reports 2Health News:DePuy Pinnacle Hip Lawsuits Move Forward, as Federal Judge Denies Hospital Bid for $1000 Explant Fee, Bernstein Liebhard LLP Reports 3Health News:DePuy Pinnacle Hip Lawsuits Move Forward, as Federal Judge Denies Hospital Bid for $1000 Explant Fee, Bernstein Liebhard LLP Reports 4Health News:Study links enzyme to autistic behaviors 2Health News:Study links enzyme to autistic behaviors 3Health News:HIV clinic-based audio project emphasizes the power of patient voices 2Health News:HIV clinic-based audio project emphasizes the power of patient voices 3Health News:US Olympian Chad Hedrick Visits Foot Levelers 2Health News:Dogs Can Get Jealous, Too 2
... Abbott, has agreed to lower the prices of Kaletra/Aluvia ... US dollars, on a request from the World Health ... indicated for the treatment of HIV-1 infected adults and ... with other antiretroviral agents. It is in a category ...
... in the April 10, 2007, issue of Neurology, has ... suffering ‘Restless Legs Syndrome (RLS). The risk increases in ... at the University of Montreal’s Sacré-Coeur Hospital, ten people ... laboratory, where researchers monitored periodic leg movements and blood ...
... groups are joining forces to fund three promising lung ... Society// are contributing $370,000 to fund the first-ever LUNGevity ... The grants will go to three researchers whose novel ... cancer develops and could lead to more effective treatments. ...
... to a survey, which was carried out to mark Mental ... respondents know two friends// who have experienced mental distress at ... showed that almost 90 percent of those suffering from mental ... of shame for appearing weak or because they felt their ...
... Public Health has found that the state level rates of suicide ... ownership of firearm. ,"We found that where there ... Professor of Health Policy and Management at HSPH and lead author ... 15 leading causes of death in the U.S.; among persons less ...
... entire life from one moment to the next, and experts ... than the psychological after-effects. ,"Every person reacts differently ... emergency rescue services in the northern German port city of ... shock like screaming is seldom the case, she says. "Some ...
Cached Medicine News:Health News:Abbott to Subsidize Price of HIV Drug 2Health News:Restless Legs Syndrome Poses Risk of Cardiovascular Disease 2Health News:Groups Join Forces to Fund Promising Lung Cancer Research 2Health News:Household Guns Associated With Higher Rates of Suicide in US 2Health News:Accident Victims Often Need Psychological Help 2
(Date:7/23/2014)... , July 23, 2014 Research ... the "Global Electrophysiology Ablation Catheters Market 2014-2018" ... http://photos.prnewswire.com/prnh/20130307/600769 Catheter ablation ... or destroy faulty electrical pathways from sections of ... known as cardiac arrhythmias). Cardiac arrhythmias can be ...
(Date:7/23/2014)... 23, 2014 Creekridge Capital, an independent ... new vendors so far in 2014 to their ... vendors are from both the healthcare and technology ... large, well-known multi-national companies. Each of these new ... financing products including: standard leasing products, subscription solutions, ...
(Date:7/23/2014)... MINNEAPOLIS , July 23, 2014  Nonin Medical, ... leader in noninvasive medical monitoring, announced today that ... OEM, has been elected Chairman of the American Telemedicine ... Board of Directors. The ATA is the ... advanced remote medical technologies. The ATA and its diverse ...
Breaking Medicine Technology:Global Electrophysiology Ablation Catheters Market 2014-2018: Key Vendors are Boston Scientific, Johnson & Johnson, Medtronic and St. Jude Medical 2Global Electrophysiology Ablation Catheters Market 2014-2018: Key Vendors are Boston Scientific, Johnson & Johnson, Medtronic and St. Jude Medical 3Creekridge Capital Signs Several New Vendor Partners 2Nonin Medical Announces that Mark VanderWerf has been Elected Chairman of the American Telemedicine Association's Industry Council 2
... QGLY ) today reported net sales of $11.8 ... to $11.5 million,reported for the same period in 2006. ... $25.9 million compared to $27.9 million reported,for the same ... nine months of 2007 reflect a net sales,increase for ...
... parents provide different responses ... ORLANDO, Fla., Oct. 25 According ... parents have,significantly different perceptions of the importance ... the patients, most,concerning behavior. The study, which ...
Cached Medicine Technology:The Quigley Corporation Reports Third Quarter Results, Increases Investment in Pharmaceutical R&D for Diabetic Neuropathy 2The Quigley Corporation Reports Third Quarter Results, Increases Investment in Pharmaceutical R&D for Diabetic Neuropathy 3The Quigley Corporation Reports Third Quarter Results, Increases Investment in Pharmaceutical R&D for Diabetic Neuropathy 4The Quigley Corporation Reports Third Quarter Results, Increases Investment in Pharmaceutical R&D for Diabetic Neuropathy 5The Quigley Corporation Reports Third Quarter Results, Increases Investment in Pharmaceutical R&D for Diabetic Neuropathy 6The Quigley Corporation Reports Third Quarter Results, Increases Investment in Pharmaceutical R&D for Diabetic Neuropathy 7A Sociolinguistic Analysis of In-Office Dialogue Reveals Psychiatrists and Parents Have Significantly Different Perceptions on ADHD and Psychiatric Comorbidities 2A Sociolinguistic Analysis of In-Office Dialogue Reveals Psychiatrists and Parents Have Significantly Different Perceptions on ADHD and Psychiatric Comorbidities 3A Sociolinguistic Analysis of In-Office Dialogue Reveals Psychiatrists and Parents Have Significantly Different Perceptions on ADHD and Psychiatric Comorbidities 4
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: