Navigation Links
New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes
Date:11/21/2008

p to drug exposure.
Hypersensitivity reactions include anaphylaxis, angioedema, rash, urticaria, and exfoliative skin conditions including Stevens-Johnson syndrome [see Warnings and Precautions (5.3); hepatic enzyme elevations.

  • DRUG INTERACTIONS

  • Digoxin

There was a slight increase in the area under the curve (AUC, 11%) and mean peak drug concentration (Cmax, 18%) of digoxin with the co-administration of 100mg sitagliptin for 10 days. Patients receiving digoxin should be monitored appropriately. No dosage adjustment of digoxin or JANUVIA is recommended.

  • USE IN SPECIFIC POPULATIONS

  • Pregnancy

Pregnancy CategoryB:

Reproduction studies have been performed in rats and rabbits. Doses of sitagliptin up to 125mg/kg (approximately 12 times the human exposure at the maximum recommended human dose) did not impair fertility or harm the fetus. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Merck & Co., Inc. maintains a registry to monitor the pregnancy outcomes of women exposed to JANUVIA while pregnant. Health care providers are encouraged to report any prenatal exposure to JANUVIA by calling the Pregnancy Registry at (800) 986-8999.

Sitagliptin administered to pregnant female rats and rabbits from gestation day 6 to 20 (organogenesis) wa
'/>"/>

Source: PRWeb
Copyright©2008 Vocus, Inc.
All rights reserved  

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33

Related medicine news :

1. STAAR Surgical Forms Team of Leading Ophthalmic Surgeons to Study the Use of Collamer(R) Material for Accommodating Intraocular Lenses
2. Landmark study defines benefits of early HIV testing and treatment for infected infants
3. Study identifies causes of bone loss in breast cancer survivors
4. New Study by BioTrends Highlights Practice Management Shifts Among Canadian Nephrologists
5. Study Suggests Need for More Aggressive Outpatient Monitoring of Patients Hearts When Cause of Stroke is Unclear
6. Rutgers researchers study cites media violence as critical risk factor for aggression
7. Brigham and Womens Researchers Partner with Vocantas to use CallAssure in Clinical Research Study
8. Analyst Available to Comment on New JUPITER Study That Shows AstraZenecas Crestor Significantly Reduces CV Risk
9. New Study Finds CO2 Ablative Fractional Resurfacing Safe And Effective For Deep Acne Scarring
10. Study investigates Gore-tex-type device to stop strokes and mini-strokes
11. The smart way to study
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
 New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes 
(Date:6/1/2015)... Linda Kincaid, age 67, knew something was wrong. She constantly ... thought it was just a part of getting older, but ... After going to the doctor, she received a distressing diagnosis: ... might happen to her. , Linda is not alone. As ... each year. Valve disease involves damage to one or more ...
(Date:6/1/2015)... Portland, Ore. (PRWEB) June 01, 2015 ... Plans (AHIP) announced today a new, interactive Affordable ... support large employers. The course, called “Affordable Care ... care professionals with the strategic and consultative insights ... employers as they navigate the impacts of the ...
(Date:6/1/2015)... NY (PRWEB) June 01, 2015 For ... patients requesting celebrity features. Much like one would request ... stars’ noses, eyes, cheeks, chin and more to illustrate ... filtering apps like FaceTune are ushering in a new ... Manhattan facial plastic surgeon, Sam Rizk, MD, FACS notes ...
(Date:6/1/2015)... June 01, 2015 Listen to Volvo’s ... automotive companies are using more granular data to create ... comparatively new industry voices in Josep Celaya Gonzalez, CIO ... start-up ParkTAG. As an automotive insurer, MAPFRE are well ... an easy-to-use solution to the driver. Award winning start-up ...
(Date:6/1/2015)... 2015 A University of Texas ... signaling proteins that activate protein degradation, which helps ... 1 , The study published April 3rd ... Spraque-Dawley rats 2-3 months of age who performed ... given either whey protein (.4g/kg), low-dose Sustamine (.1g/kg), ...
Breaking Medicine News(10 mins):Health News:A New Online Resource for Those Living with Heart Valve Disease 2Health News:A New Online Resource for Those Living with Heart Valve Disease 3Health News:Cambia Partners with AHIP to Offer Expert Series ACA Training Course 2Health News:Cambia Partners with AHIP to Offer Expert Series ACA Training Course 3Health News:Instagram Filters Launch New Facial Plastic Surgery Trend 2Health News:Complimentary Webinar: Volvo, MAPFRE and Award Winning Start-Up discuss new Frontier of In-Car Services 2Health News:Study Shows Taking Sustamine® L-Alanyl-L-Glutamine May Reduce Muscle Protein Breakdown After Resistance Exercise 2Health News:Study Shows Taking Sustamine® L-Alanyl-L-Glutamine May Reduce Muscle Protein Breakdown After Resistance Exercise 3
... of poor children with congenital heart diseases (CHD) here moved ... the US by a non-profit organization. About 40-50 NRIs have ... keen to sponsor a child or two every year ... born in India with CHD. Only six to eight percent ...
... devised a new system that ranks foods according to ... and developed// by a panel of independent nutritionists, dietitians, ... as well as members of the government’s Scientific Advisory ... developed by the UK’s Food Standards Agency (FSA) has ...
... change in the genetic constitution is what makes each ... is unraveled, then health care can be individualized according ... same genetic code, how those genes express themselves at ... medicines and dietary advice. According to a recent study, ...
... among couples who smoke according to a new study// which ... stroke than cigarette-smoking women with non-smoking spouses. ,The study ... total stroke and ischemic stroke (a stroke caused by a ... groups of women. The relative risk of total stroke was ...
... fine combing of wet hair may be far more ... ,Researchers have used single blind randomized controlled trial ... counter insecticide treatments against head lice in United Kingdom. ... more effective than current over the counter chemical treatments ...
... with severe asthma according to a recent study.// This ... of antioxidants such as vitamin C and incidence of ... intakes and blood concentrations of antioxidants, including vitamin C, ... without asthma. , ,Men with severe asthma had ...
Cached Medicine News:Health News:Nutrient Profiling System Launched By Food Officials in UK 2Health News:Learning Just How Different We Are 2Health News:Combing Hair More Effective Than OTC Medicine For Head Lice 2
(Date:6/1/2015)... Novel t reatments   entering the ... GBI Research . ... driven primarily by the introduction of numerous premium therapies, particularly ... or combine with generic chemotherapies. Analysis from business ... Market to 2020 - forecasts the value of the ...
(Date:6/1/2015)... , June 1, 2015 Symbiotix Biotherapies, ... $2.3 million Phase 2 Small Business Technology Transfer (STTR) ... National Institute of Allergy and Infectious Diseases (NIAID). The ... developing a novel class of molecular therapeutics from ... clinical candidate, Polysaccharide A (PSA), is the first molecule ...
(Date:6/1/2015)... June 1, 2015   OTC Markets Group ... and Connected financial marketplaces for 10,000 U.S. and ... San Diego -based biopharmaceutical company, on ... America,s only public venture market for entrepreneurial and ... http://photos.prnewswire.com/prnh/20110118/MM31963LOGO "We,re happy to ...
Breaking Medicine Technology:New Therapies to Enhance Increasingly Competitive Non-Small Cell Lung Cancer Treatment Market 2New Therapies to Enhance Increasingly Competitive Non-Small Cell Lung Cancer Treatment Market 3Symbiotix Biotherapies Announces $2.3 Million Award from NIH's National Institute of Allergy and Infectious Diseases (NIAID) 2OTC Markets Group Congratulates OncoSec Medical on NASDAQ Listing 2
... /PRNewswire-Asia/ -- Bristol-Myers Squibb Company (NYSE: ... (NYSE: SCR ), a leading pharmaceutical company ... the strategic partnership formed last year to include a ... agreed to co-develop BMS-795311, Bristol-Myers Squibb,s preclinical small molecule ...
... SAN DIEGO, Dec. 13, 2011  BioMed Realty Trust, Inc. ... has entered into a definitive agreement to acquire Prudential ... Street properties.  BioMed previously acquired a 20% interest in ... venture entered into between BioMed and PREI.  The Rogers ...
Cached Medicine Technology:Simcere and Bristol-Myers Squibb Enter Innovative Partnership to Develop Cardiovascular Compound 2Simcere and Bristol-Myers Squibb Enter Innovative Partnership to Develop Cardiovascular Compound 3Simcere and Bristol-Myers Squibb Enter Innovative Partnership to Develop Cardiovascular Compound 4Biomed Realty Trust to Acquire Remaining 80% Interest in Rogers Street Properties in Cambridge, Massachusetts for $308 Million - Increasing Ownership to 100% 2Biomed Realty Trust to Acquire Remaining 80% Interest in Rogers Street Properties in Cambridge, Massachusetts for $308 Million - Increasing Ownership to 100% 3Biomed Realty Trust to Acquire Remaining 80% Interest in Rogers Street Properties in Cambridge, Massachusetts for $308 Million - Increasing Ownership to 100% 4
Coibri handle. Pierse tips with 6 mm platform. 2.5 mm angled tips. Manufactured in titanium....
Straight shafts with 2.0 mm, 1 x 2 Elschnig style teeth. Serrated handle with polished finish. Handle: Wide....
Straight shafts with 45 degrees, 0.12 mm, 2 x 3 teeth and tying platform. Serrated handle with polished finish....
Straight shafts with 0.1 mm Pierse tips. Flat smooth handle with dull finish....
Medicine Products: