Navigation Links
New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes
Date:11/21/2008

-height:1.5em; list-style-image: url(/images_v4/bullet_solid2.gif);">
  • the prespecified pooled analysis of the two monotherapy studies, the add-on to metformin study, and the add-on to pioglitazone study, the overall incidence of adverse reactions of hypoglycemia in patients treated with JANUVIA 100mg was similar to placebo (1.2% vs 0.9%). Adverse reactions of hypoglycemia were based on all reports of hypoglycemia; a concurrent glucose measurement was not required. The incidence of selected gastrointestinal adverse reactions in patients treated with JANUVIA was as follows: abdominal pain (JANUVIA 100mg, 2.3%; placebo, 2.1%), nausea (1.4%, 0.6%), and diarrhea (3.0%, 2.3%).

    • an additional, 24-week, placebo-controlled factorial study of initial therapy with sitagliptin in combination with metformin, the adverse reactions reported (regardless of investigator assessment of causality) in >=5% of patients are shown in Table 2. The incidence of hypoglycemia was 0.6% in patients given placebo, 0.6% in patients given sitagliptin alone, 0.8% in patients given metformin alone, and 1.6% in patients given sitagliptin in combination with metformin.

    Table 2

    Initial Therapy with Combination of Sitagliptin and Metformin:

    Adverse Reactions Reported (Regardless of Investigator Assessment of Causality) in >=5% of PatientsReceiving Combination Therapy (and Greater than in Patients Receiving Metformin alone, Sitagliptinalone, and Placebo)†

    Number of Patients (%) Placebo

    Sitagliptin(JANUVIA)100 mg QD

    Metformin500 or 1000 mg bid ††

    Sitagliptin50 mg bid +Metformin500 or 1000 mg bid ††

    N = 176 N = 179 N = 364†† N = 372†† Upper Respiratory Infection 9 (5.1) 8 (4.5) 19 (5.2) 23 (6.2) Headache 5 (2.8) 2 (1.1) 14
    '/>"/>

    Source: PRWeb
    Copyright©2008 Vocus, Inc.
    All rights reserved  

    Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33

    Related medicine news :

    1. STAAR Surgical Forms Team of Leading Ophthalmic Surgeons to Study the Use of Collamer(R) Material for Accommodating Intraocular Lenses
    2. Landmark study defines benefits of early HIV testing and treatment for infected infants
    3. Study identifies causes of bone loss in breast cancer survivors
    4. New Study by BioTrends Highlights Practice Management Shifts Among Canadian Nephrologists
    5. Study Suggests Need for More Aggressive Outpatient Monitoring of Patients Hearts When Cause of Stroke is Unclear
    6. Rutgers researchers study cites media violence as critical risk factor for aggression
    7. Brigham and Womens Researchers Partner with Vocantas to use CallAssure in Clinical Research Study
    8. Analyst Available to Comment on New JUPITER Study That Shows AstraZenecas Crestor Significantly Reduces CV Risk
    9. New Study Finds CO2 Ablative Fractional Resurfacing Safe And Effective For Deep Acne Scarring
    10. Study investigates Gore-tex-type device to stop strokes and mini-strokes
    11. The smart way to study
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    Related Image:
     New Study Data: JANUVIA™ (sitagliptin) Significantly Reduced Blood Sugar Levels and Was Not Associated with Hypoglycemia in Elderly Patients with Type 2 Diabetes 
    (Date:7/25/2014)... The North America Artificial lift market report ... with analysis and forecast of revenue. The artificial lift market ... billion in 2013 to around $7 billion by 2018, at ... Browse through the TOC of North America artificial lift market ... also provides a glimpse of the segmentation in North America ...
    (Date:7/25/2014)... Agoura Hills dentist , Dr. Amir ... Zoom Whitening is one of the most powerful whitening treatments ... professional. This light-assisted treatment uses a prescription-strength gel that can ... to break up stains that are in both the enamel ... soft drink and tobacco stains. , About Dr. Amir ...
    (Date:7/25/2014)... July 25, 2014 The rising pharmaceutical sale ... to the growth of the US PBM industry. A slow ... value of pharmaceutical sales in the US over the past ... attributed to rise in the prescription volume over the past ... Benefit Management (PBM): 2013 Edition” the demand for the pharmacy ...
    (Date:7/25/2014)... 25, 2014 Ross A. Clevens, MD, ... invited to join the exclusive Obagi Clinical Advisory Board, ... plastic surgeons, plastic surgeons and dermatologists. , Dr. ... Advisory Board of thought leaders held its first meeting ... was to give Obagi the opportunity to meet with ...
    (Date:7/25/2014)... FRIDAY, July 25, 2014 (HealthDay News) -- Dietary changes ... gut on a daily basis, according to a new ... systems that might help detect and ease flare-ups for ... disease (ulcerative colitis and Crohn,s disease), the researchers said. ... but their effect on human health isn,t well understood, ...
    Breaking Medicine News(10 mins):Health News:North America Artificial Lift Services Market is Expected to Reach $7 Billion in 2018 - New Report by MicroMarket Monitor 2Health News:North America Artificial Lift Services Market is Expected to Reach $7 Billion in 2018 - New Report by MicroMarket Monitor 3Health News:North America Artificial Lift Services Market is Expected to Reach $7 Billion in 2018 - New Report by MicroMarket Monitor 4Health News:Agoura Hills Dentist, Dr. Amir Choroomi, is Now Offering a Promotion on Zoom Whitening 2Health News:US Pharmacy Benefit Management (PBM) Market Trends and Developments Now Available at MarketReportsOnline.com 2Health News:US Pharmacy Benefit Management (PBM) Market Trends and Developments Now Available at MarketReportsOnline.com 3Health News:Renowned Melbourne Plastic Surgeon to Join Private Medical Advisory Board 2Health News:Diet Changes Can Alter Gut Bacteria, Study Says 2
    ... 10 The Community Oncology Alliance (COA) today issued a ... their practices if critical Medicare reimbursement fixes for treating cancer ... reform. , "Current health reform legislation before Congress does not ... in January to cancer care," said Patrick Cobb, ...
    ... , SACRAMENTO, Calif., Dec. 10 ... California Affiliates of Susan G. Komen for the Cure® signaled ... Every Woman Counts program, which would effectively shut ... low-income and uninsured women for the first six months of ...
    ... A never-approved drug developed to prevent the death of nerve ... keeping normal cells healthy and intact, an international team led ... journal Breast Cancer Research . Prof. Malka ... stroke drug a member of a family of phenanthridine ...
    ... ... Laser-type device to be ... San Diego (PRWEB) ... jointly entered into a letter of intent with Advanced Light Devices to develop a proprietary laser system. It ...
    ... , SILVER SPRING, Md., Dec. 10 The U.S. ... approved to replace a portion of plasma used when storing ... donor plasma to be used for other purposes. , (Logo: ... platelets, which are blood components that help with blood clotting, ...
    ... SALEM, Ore., Dec. 10 West Coast Bank,s Salem Battle Creek ... hospitalized at the Salem Hospital Pediatric Wing and Neonatal Intensive Care ... branch, 5686 Commercial St. SE, Suite 110 on week days from ... Manager of Pediatrics at Salem Hospital said, "The hospital is in ...
    Cached Medicine News:Health News:National Oncologist Group Warns: Current Health Care Reform Legislation Woefully Short in Addressing Cancer Care Crisis 2Health News:National Oncologist Group Warns: Current Health Care Reform Legislation Woefully Short in Addressing Cancer Care Crisis 3Health News:National Oncologist Group Warns: Current Health Care Reform Legislation Woefully Short in Addressing Cancer Care Crisis 4Health News:California Breast Cancer Survivors and Advocates Call on State to Nix Screening Cuts 2Health News:California Breast Cancer Survivors and Advocates Call on State to Nix Screening Cuts 3Health News:Finding the Achilles' heel of cancer 2Health News:Entest BioMedical Enters into LOI with Advanced Light Devices to Develop Laser Platform for Stem Cell / Laser COPD Treatment 2Health News:Entest BioMedical Enters into LOI with Advanced Light Devices to Develop Laser Platform for Stem Cell / Laser COPD Treatment 3Health News:FDA Approves First Additive Solution for Platelet Storage Up to 5 Days 2
    (Date:7/24/2014)... , July 24, 2014   AcelRx Pharmaceuticals, Inc. ... focused on the development and commercialization of innovative therapies ... confirmed the PDUFA date for Zalviso remains July 27, ... rumor circulated online stating the Food and Drug Administration ... there has been no notification to the company from ...
    (Date:7/24/2014)... , July 24, 2014  Restore Health, ... and compounded pharmaceuticals, announced that it is now ... unique to each individual based upon their particular ... by understanding the interaction between a patient,s genetics ... "We,re very excited to provide this new service ...
    (Date:7/24/2014)... 24, 2014  Uroplasty, Inc. (NASDAQ: UPI ... and markets innovative proprietary products to treat voiding ... 2015 first quarter ended June 30, 2014.  ... Neuromodulation System grew 19% to $4.1 million, as ... of the prior year.  Total revenue for the ...
    Breaking Medicine Technology:AcelRx Pharmaceuticals Confirms July 27, 2014 PDUFA Date for Zalviso 2Restore Health Launches Pharmacogenetic Testing, Enhancing Its Suite of Personalized Medicine Goods and Services 2Restore Health Launches Pharmacogenetic Testing, Enhancing Its Suite of Personalized Medicine Goods and Services 3Uroplasty Reports Fiscal First Quarter Results 2Uroplasty Reports Fiscal First Quarter Results 3Uroplasty Reports Fiscal First Quarter Results 4Uroplasty Reports Fiscal First Quarter Results 5Uroplasty Reports Fiscal First Quarter Results 6Uroplasty Reports Fiscal First Quarter Results 7Uroplasty Reports Fiscal First Quarter Results 8Uroplasty Reports Fiscal First Quarter Results 9Uroplasty Reports Fiscal First Quarter Results 10Uroplasty Reports Fiscal First Quarter Results 11
    ... Feb. 24, 2011 Reportlinker.com announces that a ... catalogue: Global Computer Assisted ... http://www.reportlinker.com/p0397748/Global-Computer-Assisted-Surgical-CAS-Systems-Industry.html This report analyzes ... Systems in US$ Million by the following Product ...
    ... Reportlinker.com announces that a new market research report is ... Drug-Eluting Stents Industry http://www.reportlinker.com/p080457/Global-Drug-Eluting-Stents-Industry.html ... for Drug-Eluting Stents in US$ Million. The report provides ... Rest of World. Annual estimates and forecasts are provided ...
    Cached Medicine Technology:Reportlinker Adds Global Computer Assisted Surgical (CAS) Systems Industry 2Reportlinker Adds Global Drug-Eluting Stents Industry 2
    ... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
    ... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
    ... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
    ... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
    Medicine Products: