Digestive Disease Week study examined ACR's guidelines for CT colonography inte... (fore these lesions progress to advanced ...)

Digestive Disease Week study examined ACR's guidelines for CT colonography interpretation

Date:7/10/2008

fore these lesions progress to advanced disease. Researchers looked to characterize pancreatic neoplastic lesions detected by imaging tests in high risk individuals; to compare the diagnostic yield and incremental benefit of EUS over CT/MRCP; and to determine the incremental benefit of fine needle aspiration (FNA) over EUS alone.

Data prospectively collected from 1998-2007 from two screening studies and the center's clinical screening program were analyzed. High risk individuals with Peutz-Jeghers syndrome or first degree relatives from familial ductal adenocarcinoma kindreds with at least two affected, had either multi-detector CT and or MRI/MRCP, and EUS. Radiologic and EUS features of each preoperatively detected lesion were compared with the pathologic findings. The diagnostic yield of each imaging modality was calculated on a per lesion basis.

Of 165 patients who had EUS and CT/MRCP, 19 asymptomatic high risk individuals underwent partial resection (15), partial followed by completion pancreatectomy (3), or total pancreatectomy (1) for 44 pancreatic lesions (size range 2.6-21 mm) detected by EUS, CT or MRCP. Researchers concluded that most pancreatic neoplasms detected by screening tests are small and low grade, but six percent of intraductal papillary mucinous neoplasms < 3 cm may contain high grade dysplasia. EUS detects almost twice as many neoplastic lesions as CT/MRCP, regardless of size, and FNA adds little to EUS.

Peroral Cholangioscopy Guided Stone Therapy C Report of an International Multicenter Registry

A study by Mansour A. Parsi, MD, department of gastroenterology at the Cleveland Clinic Foundation, examined peroral cholangioscopy used for the management of biliary stones that cannot be removed by conventional methods. The need for two expert operators and technical limitations of cholangioscopes has hampered its widespread adoption for the management of difficult to remove biliary stones. Researchers exa
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Contact: Anne Brownsey
abrownsey@asge.org
630-570-5635
American Society for Gastrointestinal Endoscopy
Source:Eurekalert

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