Bruker Daltonics today is showcasing several new high performance mass spectrometry products and applications for proteomics at the 7th HUPO World Congress 2008:
AMSTERDAM, The Netherlands (Business Wire EON) August 17, 2008 -- maXis™ is the world's first high speed Ultra High Resolution TOF (UHR-TOF) mass spectrometer platform, and truly represents a revolution in tandem mass spectrometry. maXis offers exceptional proteomics performance with sub-ppm mass accuracy, mass resolution of 40,000 to 60,000 across a broad mass range, outstanding sensitivity and five orders of dynamic range - all at the high spectral rate of 20 Hz for MS and MS/MS that is essential for quantitative proteomics and to take full advantage of ultra-high performance liquid chromatography. ETD II is the next-generation electron transfer dissociation module for Bruker's HCTultra™ high capacity ion trap. It is based on a novel and compact nCI (negative chemical ionization) source with increased ETD/PTR reactant ion generation, resulting in rapid, confident characterization of PTMs such as phosphorylations or glycosylations at sub-fmol sensitivity. In combination with the major and fundamental ETD efficiency and sensitivity advantages of the spherical high capacity trap design, ETD II is designed to provide the most sensitive, fastest and most robust ETD fragmentation. Due to HCTultra's inherent m/z range of greater 3,000 and its superior mass resolution that can resolve 3+ and 4+ charge states of peptides on-the-fly at full analytical speed, ETD/PTR on the HCT-Ultra can even be used for up to 12 kDa proteins and beyond. MALDI-TDS™ Top-Down Sequencing (TDS) solution provides unparalleled levels of information from undigested proteins in pharmaceutical and biotechnology applications, including C- and N- terminal assignments even in the case of N-terminally blocked proteins. MALDI-TDS is available on Bruker's top-of-
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