Navigation Links
Nosespray vaccine using aloe vera has exciting potential, researcher says

COLLEGE STATION, Sept. 25, 2007 -- Researchers at Texas A&M University are participating in developing a medicine that is worth sneezing about: a treatment for influenza that forms a jelly when sprayed into the nose.

Even though trial treatments are being used to treat bird flu in humans, technically termed the H5N1 virus, the vaccine has the potential for numerous other uses, such as for the common flu shot, says Dr. Ian Tizard, professor of pathobiology in the College of Veterinary Medicine & Biomedical Sciences.

The project is funded in part by a $6 million grant from the National Institutes of Health awarded to DelSite Biotechnologies in conjunction with the Texas A&M teams. DelSite, an Irving-based company, has a facility in College Station.

Tizard says the method in which the vaccine gets delivered into the body is the key to the new treatment.

We take Aloe vera leaves and put them through a series of complex extraction steps to produce a chemically pure powder, and then we combine the flu vaccine with it, he explains.

When this powder vaccine is puffed into the nose, it forms a jelly-like substance that clings to the inside of the nose and is absorbed into the body much more effectively. It stays longer and it has more time to do its work.

Tizard says one or two puffs into the nose is all thats needed in most cases to get good results. This powder form is more effective than a liquid spray because the nose tends to clear liquid sprays out, while the powder turns into a sticky gel and can be a much more potent vaccine.

Also, in this powder form, it can be stored for a long period of time, which is great news if thousands or even millions of doses should be needed in the case of an emergency. Aloe vera plants are native to North Africa but can be found worldwide. There are more than 100 species of Aloe vera.

Tizard, who has conducted research using Aloe vera plants for many years, says the special carbohydrate in Aloe vera leaves is perfect for forming the gel-like substance needed to act as a carrier for the vaccine.

Tests using the new vaccine have been successful in animal trials, Tizard says, and tests on humans will begin next year.

The plan was to try this first as a vaccine for bird flu in humans because there was an immediate concern there, and there still is the possibility that a widespread bird flu epidemic could break out somewhere in the world, Tizard adds.

But there is no reason to think this method of vaccine treatment would not work for many other diseases, too. We think its an exciting breakthrough that has great potential.


Contact: Keith Randall
Texas A&M University

Related medicine news :

1. Vaccine to quit smoking?
2. First Vaccine Designed for Africa Cleared for Testing in Humans
3. New hope for cancer victims – will vaccine cure the deadly bug
4. Vaccine for Alzheimer’s diseas
5. New vaccine helps allergy and asthma patients
6. Man against HIV – new vaccine ready for human trials
7. New vaccine helps allergy and asthma patients
8. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
9. HIV did not arise from polio vaccine
10. Double impact vaccine
11. Vaccine Reduces antibiotic-resistant infections in Children
Post Your Comments:
(Date:12/1/2015)... ... 01, 2015 , ... Visage accelerates mobile imaging results access ... of Pro Medicus Ltd. (ASX: PME), has announced they are demonstrating new work-in-progress ... (RSNA) 2015 annual meeting through December 3 in Chicago, Illinois, at Booth #1350, ...
(Date:12/1/2015)... ... December 01, 2015 , ... ... been selected as a finalist in this year’s Fierce Innovation Awards: Healthcare Edition, ... Healthcare was recognized as a finalist in the category of Digital Solutions for ...
(Date:12/1/2015)... ... December 01, 2015 , ... Lutronic, a leading innovator ... the latest addition to the devices for sale in the United States. Clarity ... and long-pulsed 1064 nm Nd:YAG lasers, into a single platform that is easy to ...
(Date:12/1/2015)... ... December 01, 2015 , ... PYA’s latest ... Integration ,” addresses a main “pain point” for merging or aligning healthcare provider ... a deal is signed. This quick-read guidance suggests that failing to recognize ...
(Date:12/1/2015)... ... December 01, 2015 , ... ... and SACC-USA through membership and leadership since 2008. Gary Bruce, President of ... SACC-USA . Gary has spent a significant amount of time in Sweden since ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... , Dec. 1, 2015  AccuTEC Blades, a ... new corporate logo and brand identity program. The ... and engineering of bladed products where "the edge ... --> Serving manufacturers and distributors ... auto glass equipment, AccuTEC,s product lines include those ...
(Date:12/1/2015)... , Dec. 1, 2015 Building ... HIV/AIDS, Johnson & Johnson (NYSE: JNJ ) ... Janssen Pharmaceutical Companies to significantly reduce the burden ... make up 74 percent of new HIV infections ... on World AIDS Day, these new initiatives include ...
(Date:12/1/2015)... , December 1, 2015 ... Contraceptive Injectables, Topical Contraceptives, Male Condoms, Female ... Vaginal Rings, Contraceptive Diaphragms, Contraceptive Sponges, Non-Surgical ... Size, Share, Growth, Trends and Forecast 2014 ... Transparency Market Research (TMR).The report states that ...
Breaking Medicine Technology: