Navigation Links
Nosespray vaccine using aloe vera has exciting potential, researcher says
Date:9/25/2007

COLLEGE STATION, Sept. 25, 2007 -- Researchers at Texas A&M University are participating in developing a medicine that is worth sneezing about: a treatment for influenza that forms a jelly when sprayed into the nose.

Even though trial treatments are being used to treat bird flu in humans, technically termed the H5N1 virus, the vaccine has the potential for numerous other uses, such as for the common flu shot, says Dr. Ian Tizard, professor of pathobiology in the College of Veterinary Medicine & Biomedical Sciences.

The project is funded in part by a $6 million grant from the National Institutes of Health awarded to DelSite Biotechnologies in conjunction with the Texas A&M teams. DelSite, an Irving-based company, has a facility in College Station.

Tizard says the method in which the vaccine gets delivered into the body is the key to the new treatment.

We take Aloe vera leaves and put them through a series of complex extraction steps to produce a chemically pure powder, and then we combine the flu vaccine with it, he explains.

When this powder vaccine is puffed into the nose, it forms a jelly-like substance that clings to the inside of the nose and is absorbed into the body much more effectively. It stays longer and it has more time to do its work.

Tizard says one or two puffs into the nose is all thats needed in most cases to get good results. This powder form is more effective than a liquid spray because the nose tends to clear liquid sprays out, while the powder turns into a sticky gel and can be a much more potent vaccine.

Also, in this powder form, it can be stored for a long period of time, which is great news if thousands or even millions of doses should be needed in the case of an emergency. Aloe vera plants are native to North Africa but can be found worldwide. There are more than 100 species of Aloe vera.

Tizard, who has conducted research using Aloe vera plants for many years, says the special carbohydrate in Aloe vera leaves is perfect for forming the gel-like substance needed to act as a carrier for the vaccine.

Tests using the new vaccine have been successful in animal trials, Tizard says, and tests on humans will begin next year.

The plan was to try this first as a vaccine for bird flu in humans because there was an immediate concern there, and there still is the possibility that a widespread bird flu epidemic could break out somewhere in the world, Tizard adds.

But there is no reason to think this method of vaccine treatment would not work for many other diseases, too. We think its an exciting breakthrough that has great potential.


'/>"/>

Contact: Keith Randall
keith-randall@tamu.edu
979-845-4644
Texas A&M University
Source:Eurekalert

Related medicine news :

1. Vaccine to quit smoking?
2. First Vaccine Designed for Africa Cleared for Testing in Humans
3. New hope for cancer victims – will vaccine cure the deadly bug
4. Vaccine for Alzheimer’s diseas
5. New vaccine helps allergy and asthma patients
6. Man against HIV – new vaccine ready for human trials
7. New vaccine helps allergy and asthma patients
8. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
9. HIV did not arise from polio vaccine
10. Double impact vaccine
11. Vaccine Reduces antibiotic-resistant infections in Children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... ... August 18, 2017 , ... As an industry leader, Eppendorf ... they will present the line of epMotion automated liquid handling system. This automated ... automate everyday pipetting tasks. , Ideal for scientists and lab technicians with no ...
(Date:8/18/2017)... ... August 18, 2017 , ... Radabaugh ... protection assistance to communities in North-Central West Virginia, is embarking on a cooperative ... boys in the area. , The Chestnut Mountain Ranch (CMR) is a Christ-centered ...
(Date:8/18/2017)... IN (PRWEB) , ... August 18, 2017 , ... The ... communities in northwest Indiana, is campaigning in support of Campagna Academy in a charity ... to as the “Hoosier Boys’ Town of Indiana,” Campagna Academy is a nonprofit organization ...
(Date:8/18/2017)... ... August 18, 2017 , ... “Emotions are sacred, valid, honored, encouraged. This ... positive education company Generation Mindful. To help change the mindset of parents and educators ... skills, she created the Time-In Toolkit, which launched on Kickstarter 3 weeks ago and ...
(Date:8/18/2017)... ... August 18, 2017 , ... Alcovit, a lime-flavored beverage that rids the ... efforts with its product now available through Jet.com. , After 25 years of ... powdered drink is designed to quickly detox the body thereby avoiding alcohol-induced hangovers. Whether ...
Breaking Medicine News(10 mins):
(Date:8/8/2017)... Second-quarter 2017 revenues of $876 ... from continuing operations Second-quarter ... $110 million Second-quarter 2017 ... Second-quarter 2017 adjusted diluted ... percent to $0.93 Second-quarter ...
(Date:8/7/2017)...  Endo International plc (NASDAQ: ENDP ) ... all known U.S. mesh product liability claims and that ... remaining U.S. claims at reasonable values. Under the agreements, ... quarter of 2017 and continuing through the fourth quarter ... results, the Company intends to increase its mesh product ...
(Date:8/2/2017)... and BENTON, Ky. , Aug. 2, 2017   Marshall County ... its environmental services (ES) team to proactively reduce the risk of hospital-acquired infections (HAIs). The ... disinfection robot that uses UVC light energy to kill deadly pathogens such as C. ... Tru-D SmartUVC ... Tru-D in action in ...
Breaking Medicine Technology: