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£5 million investment in personalized medicines to cut patient deaths
Date:9/5/2007

  • Acute coronary syndrome and variability in response to treatments
  • Non steroidal anti-inflammatory drug (NSAID)-induced peptic ulceration

    Professor Pirmohamed said: The study of pharmacogenetics is vital to the public health of this country. One of our recent studies showed that at any one time the equivalent of more than seven 800-bed hospitals are taken up with the patients who have suffered the side effects of drugs they have been prescribed.

    This new investment will allow Liverpool to tackle this problem by providing the evidence base that is necessary to revolutionise the way important illnesses are treated in the UK and worldwide.

    It is important to note that the way we respond to drugs is determined not only by genetic factors but also by environmental factors such as our diet and if we smoke. Through this comprehensive research strategy, we will build up a very detailed clinical picture of each individual patient and link it to genetic profiles with the aim of maximising the efficacy and reducing the potential toxicity of treatments.

    Minister for Health, Ben Bradshaw MP, said: I am delighted to announce the award of the contract to host the NHS Chair in Pharmacogenetics to the University of Liverpool. Pharmacogenetics has enormous potential to improve the effectiveness and safety of the treatment patients receive and this post will make a major contribution to both boosting research capacity and raising awareness of pharmacogenetics among NHS clinicians.

    A further 2 million has been awarded to the University by The Wolfson Foundation toward the Centre for Personalised Medicines. The unique centre will accommodate the research activity of the Chair as well as cutting-edge equipment such as a state-of-the-art DNA archiving system. The archive will hold up to 300,000 DNA samples of patients and will sort and select samples via an automated robotic system, enabling high-throughput genotypi
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  • Contact: Joanna Robotham
    joanna.robotham@liv.ac.uk
    44-015-179-42026
    University of Liverpool
    Source:Eurekalert

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