Navigation Links
$8 million NIH grant for heart cell development and study
Date:10/21/2009

macology and toxicology; and Stephen Dalton, professor and eminent scholar of biochemistry and molecular biology at the University of Georgia.

These investigators will pool their expertise to generate heart muscle from pluripotent stem cells. Pluripotent cells can be obtained from two sources. Induced pluripotent stem cells (iPSCs) are re-programmed from a patient's donor cells, which can therefore be transplanted without immune rejection. Embryonic stem cell (hESC) lines are derived from blastocysts obtained from in vitro fertilization clinics.

Specifically, the researchers will exploit the ability of stem cell-generated endoderm cells, the innermost of the three primary germ layers which induces the heart to develop in the embryo, to induce the pluripotent stem cells into cardiac myocytes, in numbers sufficient for remedial transplantation using animal models of heart disease. Therapeutic regeneration of diseased or damaged heart muscle with stem cells will depend on how efficiently the researchers can induce stem cells in culture dishes to develop into specialized endpoints of cardiac muscle maturation.

Success achieving these tasks will be promoted by synergy provided by the Medical College's many shared core facilities, and by the expertise of its world-class Cardiovascular Center and Human and Molecular Genetics Center to help meet these goals.

Ability to obtain this award was facilitated by local support from Advancing a Healthier Wisconsin, which provided grants to Drs. Duncan and Lough for preliminary aspects of the work.


'/>"/>

Contact: Toranj Marphetia
Toranj@mcw.edu
414-955-4744
Medical College of Wisconsin
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. HHS Announces $75 Million in Supplemental Funding to States for Pandemic Flu Preparedness
2. AUDIO from Medialink and Pfizer: Number of Uninsured Americans Grows to 47 Million
3. Majority of 2.4 Million U.S. Children With ADHD Not Diagnosed or Consistently Treated, According to New Gold Standard Study by Cincinnati Childrens Researchers
4. 1.5 million children could be saved
5. The Philadelphia Walk Now for Autism Expected to Draw 10,000 Walkers and Raise $1 Million to Help Find Answers About the Nations Fastest-Growing Developmental Disorder
6. UVa researcher awarded $3.6 million grant to fight drug-resistant bacteria
7. EaglePicher Corporation Completes Transaction to Sell EaglePicher Boron, LLC to Ceradyne, Inc. for $69 Million
8. R. P. Simmons Family Foundation Pledges $2 Million for New Childrens Hospital of Pittsburgh of UPMC Campus
9. £5 million investment in personalized medicines to cut patient deaths
10. Keane Wins $1 Million Electronic Medical Record (EMR) Implementation at New Jersey-Based Acute Care Facility
11. PainCare Receives $14.4 Million in Cash From Completed Sale of South Florida Ambulatory Surgery Centers
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
$8 million NIH grant for heart cell development and study
(Date:9/3/2014)... September 03, 2014 Independent review ... of appropriate evidence-based health care along the continuum. ... from the expertise of accredited independent review organizations ... care system. , As a core function, IROs ... settle questions of medical necessity. Yet backed by ...
(Date:9/2/2014)... Autumn is well under way ... the new season with worldwide people. Recently, it ... that Hostgator ( http://secure.hostgator.com/~affiliat/cgi-bin/affiliates/clickthru.cgi?id=seohosts ), Arvixe, and Bluehost ... , Since 2002 HostGator has been known ... company’s reputation for reliability remains with it today. ...
(Date:9/2/2014)... FL (PRWEB) September 03, 2014 Everyone of ... Beauty® offers two easy ways to help minimize them and ... care ingredients. Aging skin needs to boost collagen levels, which ... and sagging skin. Skin also needs to be well hydrated, ... protection from the sun and good diet that nourishes skin, ...
(Date:9/2/2014)... Chicago, IL (PRWEB) September 02, 2014 ... upcoming Ambulatory Surgery Center Educational Program on October ... Becker's ASC 21st Annual Meeting - The Business ... health system executives through high-quality continuing education, networking ... healthcare services and technologies. , Outstanding educational offerings ...
(Date:9/2/2014)... 2, 2014 4 pm EDT): In a Viewpoint published ... Association , a team of Boston researchers call for ... quality in the United States. The researchers from the ... University, Harvard University and Boston Children,s Hospital write that ... foods could both help people make meaningful dietary changes ...
Breaking Medicine News(10 mins):Health News:Independent Review Expands Its Scope: Case Studies in Context 2Health News:Independent Review Expands Its Scope: Case Studies in Context 3Health News:Top10BestSEOHosting.com Celebrates The Coming Of Autumn And Release Reseller Hosting Suppliers Of 2014 2Health News:2 Natural Ways to Relax and Reduce Wrinkles From Sublime Beauty® 2Health News:Becker's Healthcare Announces Ambulatory Surgery Center Educational Program 2Health News:Becker's Healthcare Announces Ambulatory Surgery Center Educational Program 3Health News:Taxes and subsidies could encourage healthier diet and lower healthcare costs 2
... skin cancer in men has increased by 12% in six years, ... year are now diagnosed with the disease, 3,000 of those are ... in men is that they tend to occur more commonly on ... leg and more noticeable. Up to 77% of cases are caused ...
... Research suggests that anxiety during pregnancy can increase a ... indicated that women who were very anxious// in the ... behavioural problems. ,Lead researcher Professor Vivette Glover, ... to women who had extreme anxiety, and were frequently ...
... way to predict when somebody is likely to have ... occur suddenly and without warning and can lead to ... de la Pitie-Salpetriere, Paris, believe ,it may be possible ... an electroencephalogram ,(EEG). ,An ECG records electrical activity ...
... for more than 100 years. And while most of the ... the use of aspirin has increased. This powerful pill will ... the risk of heart attacks and stroke. ,In ... were first discovered, relatively few drugs have been developed that ...
... have the option of having one blast of radiotherapy ... 25 sessions afterwards, researchers said. //They believe the new ... and may improve the treatment of breast cancer for ... world. ,Dr. Emiel Rutgers, of the Netherlands Cancer ...
... developed for preventing and treating the flue have shown ... dose to be effective.// The compounds, known collectively as ... relenza, or zanamivir, which the U.S. Food and Drug ... B. ,Researchers reported at the International Conference on ...
Cached Medicine News:
(Date:9/2/2014)... , Sept. 2, 2014 Reportlinker.com ... available in its catalogue: Acute Heart ... http://www.reportlinker.com/p0689743/Acute-Heart-Failure-Global-Clinical-Trials-Review-H2-2014.html Acute ... Summary GlobalData,s clinical trial report, ... 2014" provides data on the Acute Heart Failure ...
(Date:9/2/2014)... 2014    - Los ... agentes antitrombóticos no utilizados óptimamente para prevenir la ... presentaciones de GARFIELD-AF en el ESC CONGRESS 2014 ... resultados de pacientes en riesgo de sufrir apoplejía ... Los datos de casi 12.500 pacientes reclutados ...
(Date:9/2/2014)... , -- GARFIELD-AF ... into treatment and outcomes of patients at risk ... Data from nearly 12,500 patients enrolled ... Fibrillation (GARFIELD-AF), an innovative, independent academic research initiative, ... fibrillation (AF) patients remain sub-optimal despite the transition ...
Breaking Medicine Technology:Acute Heart Failure Global Clinical Trials Review, H2, 2014 2Acute Heart Failure Global Clinical Trials Review, H2, 2014 3Acute Heart Failure Global Clinical Trials Review, H2, 2014 4Acute Heart Failure Global Clinical Trials Review, H2, 2014 5Acute Heart Failure Global Clinical Trials Review, H2, 2014 6Acute Heart Failure Global Clinical Trials Review, H2, 2014 7Acute Heart Failure Global Clinical Trials Review, H2, 2014 8Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 2Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 3Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 4Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 5Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 6Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 7Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 8Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 9Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 10Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía 11Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 2Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 3Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 4Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 5Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 6Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 7Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 8Data From Global Atrial Fibrillation Registry Show Antithrombotic Agents Not Optimally Used to Prevent Stroke 9
... HORSHAM, Pa. , July 28 Teva Respiratory ... efficacy and safety of beclomethasone dipropionate (BDP) hydrofluoroalkane (HFA) Nasal Aerosol ... all efficacy endpoints, demonstrating a statistically significant benefit as compared to ... similar to placebo. , , ...
... BOCA RATON, Fla. , July 28 ... Pharma, the company will market Methylphenidate Solution, the generic ... an Abbreviated New Drug Application (ANDA).  Under the terms ... Tris Pharma, and marketed and distributed by Breckenridge on ...
Cached Medicine Technology:Teva Respiratory Announces Positive Results From Phase III Trial of BDP HFA Nasal Aerosol in Seasonal Allergic Rhinitis 2Teva Respiratory Announces Positive Results From Phase III Trial of BDP HFA Nasal Aerosol in Seasonal Allergic Rhinitis 3Teva Respiratory Announces Positive Results From Phase III Trial of BDP HFA Nasal Aerosol in Seasonal Allergic Rhinitis 4Teva Respiratory Announces Positive Results From Phase III Trial of BDP HFA Nasal Aerosol in Seasonal Allergic Rhinitis 5Teva Respiratory Announces Positive Results From Phase III Trial of BDP HFA Nasal Aerosol in Seasonal Allergic Rhinitis 6Breckenridge Pharmaceutical to Market Methylphenidate Oral Solution Through Agreement With Tris Pharma (Monmouth Junction, NJ) 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: