Navigation Links
$8.9 million NIH grant to study genomic link to premature heart disease
Date:9/14/2012

WINSTON-SALEM, N.C., Sept. 10, 2012 Researchers at Wake Forest Baptist Medical Center are leading a four-year, $8.9 million national project to identify variations in the human genome and corresponding changes in the arterial proteins associated with premature development of atherosclerosis.

The other institutions collaborating with Wake Forest Baptist in this project are Harvard Medical School, The Johns Hopkins UniversityBayview Campus, Virginia Polytechnic Institute and State University, Blacksburg, Va., The University of Texas Science Center at Houston, and Louisiana State Health Sciences Center, New Orleans.

The purpose of this collaborative study is to provide novel insights into the interdependent networks of genes and proteins that put some individuals at risk of premature cardiovascular disease. Ultimately, such information could lead to new screening strategies and help identify new therapeutic targets to reduce the human and financial costs of cardiovascular disease worldwide.

Researchers will analyze data from a unique, NIH-funded repository held at Louisiana State Health Sciences Center that provides data, DNA and tissue samples from 3,400 young (15- to 34-year-old) multi-ethnic subjects who died of non-cardiovascular causes.

David M. Herrington, M.D., MHS, professor of Cardiology, and principal investigator for this national collaboration, says the aim is to create a detailed molecular characterization of arterial tissue with the purpose of identifying the genetic variants associated with premature cardiovascular disease. "By using state-of-the-art molecular and analytic methods, we will be able to determine the genomic and proteomic architecture of premature atherosclerosis," Herrington said. "This will add fundamentally new knowledge about the link between the genome and the proteome in the artery wall."


'/>"/>

Contact: Paula Faria
pfaria@wakehealth.edu
336-716-1279
Wake Forest Baptist Medical Center
Source:Eurekalert

Page: 1

Related medicine news :

1. UCF nanoscientist receives $2 million NIH award
2. Saving brains in developing countries: $11.8 million for innovative ideas worldwide
3. Funding for neglected global diseases research at UBC exceeds $20 million
4. Cedars-Sinai Heart Institute awarded $1.3 million to study cardiac stem cells
5. Millions of Americans Have Uncontrolled High Blood Pressure: CDC
6. Weill Cornell awarded $1.8 million for translational blood cancer research
7. UTMB receives $1.2 million to provide HPV vaccine
8. Johns Hopkins Armstrong Institute receives $8.9 million patient safety grant
9. Germany launches a €16 million epigenome program
10. Fit Brains, online portfolio of cognitive games, reaches milestone of 75 million brain scores
11. NIH awards $7.8 million for innovative HIV vaccine approaches
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... ... October 12, 2017 , ... Leading pediatric oncology experts at Children’s ... the 49th Congress of the International Society of Paediatric Oncology (SIOP) Oct. ... Center for Cancer and Blood Disorders at Children’s National, and Stephen P. Hunger, ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... named one of Michigan’s 2017 Best and Brightest in Wellness® by Best and ... Wellness® awards program on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... in property taxes a year. In some states—like New York, New Jersey, Massachusetts, ... contrast, many overseas retirement havens have extremely low property-tax rates, which contributes to ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... of California Berkeley, and other leading institutions in announcing the launch of the ... to change the way animals are raised for food. , Founding members of ...
(Date:10/12/2017)... ... October 12, 2017 , ... Nvision Biomedical Technologies ... with the addition of industry sales leader, Thomas (Tom) Slott, as Senior Vice ... distribution and sales network, direct the efforts of the surgical sales teams, manage ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... 2017   Divoti USA will engrave and ... standard of the latest FDA requirements, which stipulates new criteria regarding ... in need of Medical ID jewelry such as Medical ID Bracelets, ... engraved in terms of the new FDA requirements . ... Divoti offers this dark mark fiber ...
(Date:10/11/2017)... , Oct. 11, 2017  Caris Life Sciences ® ... fulfilling the promise of precision medicine, today announced that ... Caris, Precision Oncology Alliance™ (POA) as its 17 th ... the St. Jude Crosson Cancer Institute will help develop ... use of tumor profiling, making cancer treatment more precise ...
(Date:10/10/2017)... Calif. , Oct. 10, 2017  NDS received FDA 510(k) ... — a medical-grade battery-powered display stand specifically designed for endoscopy environments. ... transform technology into a clinical solution to support the improvement of ... Innovative Design ... Mobile Wireless Solution ...
Breaking Medicine Technology: