Navigation Links
$8.9 million NIH grant to study genomic link to premature heart disease
Date:9/14/2012

WINSTON-SALEM, N.C., Sept. 10, 2012 Researchers at Wake Forest Baptist Medical Center are leading a four-year, $8.9 million national project to identify variations in the human genome and corresponding changes in the arterial proteins associated with premature development of atherosclerosis.

The other institutions collaborating with Wake Forest Baptist in this project are Harvard Medical School, The Johns Hopkins UniversityBayview Campus, Virginia Polytechnic Institute and State University, Blacksburg, Va., The University of Texas Science Center at Houston, and Louisiana State Health Sciences Center, New Orleans.

The purpose of this collaborative study is to provide novel insights into the interdependent networks of genes and proteins that put some individuals at risk of premature cardiovascular disease. Ultimately, such information could lead to new screening strategies and help identify new therapeutic targets to reduce the human and financial costs of cardiovascular disease worldwide.

Researchers will analyze data from a unique, NIH-funded repository held at Louisiana State Health Sciences Center that provides data, DNA and tissue samples from 3,400 young (15- to 34-year-old) multi-ethnic subjects who died of non-cardiovascular causes.

David M. Herrington, M.D., MHS, professor of Cardiology, and principal investigator for this national collaboration, says the aim is to create a detailed molecular characterization of arterial tissue with the purpose of identifying the genetic variants associated with premature cardiovascular disease. "By using state-of-the-art molecular and analytic methods, we will be able to determine the genomic and proteomic architecture of premature atherosclerosis," Herrington said. "This will add fundamentally new knowledge about the link between the genome and the proteome in the artery wall."


'/>"/>

Contact: Paula Faria
pfaria@wakehealth.edu
336-716-1279
Wake Forest Baptist Medical Center
Source:Eurekalert

Page: 1

Related medicine news :

1. UCF nanoscientist receives $2 million NIH award
2. Saving brains in developing countries: $11.8 million for innovative ideas worldwide
3. Funding for neglected global diseases research at UBC exceeds $20 million
4. Cedars-Sinai Heart Institute awarded $1.3 million to study cardiac stem cells
5. Millions of Americans Have Uncontrolled High Blood Pressure: CDC
6. Weill Cornell awarded $1.8 million for translational blood cancer research
7. UTMB receives $1.2 million to provide HPV vaccine
8. Johns Hopkins Armstrong Institute receives $8.9 million patient safety grant
9. Germany launches a €16 million epigenome program
10. Fit Brains, online portfolio of cognitive games, reaches milestone of 75 million brain scores
11. NIH awards $7.8 million for innovative HIV vaccine approaches
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... Orion, Clarkston, Michigan (PRWEB) , ... June 26, ... ... with respect to fertility once they have been diagnosed with endometriosis. These women ... intercourse but they also require a comprehensive approach that can help for preservation ...
(Date:6/25/2016)... ... , ... The temporary closing of Bruton Memorial Library on June 21 due to a possible ... often overlooked aspect of head lice: the parasite’s ability to live away from a human ... but a necessary one in the event that lice have simply gotten out of control. ...
(Date:6/25/2016)... ... , ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors ... Geffen School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green ... hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train ...
(Date:6/25/2016)... ... ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter of ... too high can result in disappointment, perhaps even self-loathing. However, those who set the ... Research from PsychTests.com reveals that behind the tendency to set low expectations ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort to ... treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain management ... (SCD) is a disorder of the red blood cells, which can cause episodes of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 The Academy of Managed Care ... that would allow biopharmaceutical companies to more easily ... make formulary and coverage decisions, a move that addresses ... medicines. The recommendations address restrictions in the ... the drug label, a prohibition that hinders decision makers ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... "The World Market for Companion Diagnostic Tests" report to ... World Market for Companion Diagnostics The World ... diagnostic and personalized medicine diagnostics. Market analysis in the report ... Diagnostics Test Market (In Vitro Diagnostic Kits) by Region (N. ...
(Date:6/24/2016)... , Belgium , June 24, ... VNRX), today announced the appointment of Dr. ... Directors as a Non-Executive Director, effective June 23, ... Audit, Compensation and Nominations and Governance Committees.  As ... Futcher will provide independent expertise and strategic counsel ...
Breaking Medicine Technology: