Navigation Links
$8.9 million NIH grant to study genomic link to premature heart disease
Date:9/14/2012

WINSTON-SALEM, N.C., Sept. 10, 2012 Researchers at Wake Forest Baptist Medical Center are leading a four-year, $8.9 million national project to identify variations in the human genome and corresponding changes in the arterial proteins associated with premature development of atherosclerosis.

The other institutions collaborating with Wake Forest Baptist in this project are Harvard Medical School, The Johns Hopkins UniversityBayview Campus, Virginia Polytechnic Institute and State University, Blacksburg, Va., The University of Texas Science Center at Houston, and Louisiana State Health Sciences Center, New Orleans.

The purpose of this collaborative study is to provide novel insights into the interdependent networks of genes and proteins that put some individuals at risk of premature cardiovascular disease. Ultimately, such information could lead to new screening strategies and help identify new therapeutic targets to reduce the human and financial costs of cardiovascular disease worldwide.

Researchers will analyze data from a unique, NIH-funded repository held at Louisiana State Health Sciences Center that provides data, DNA and tissue samples from 3,400 young (15- to 34-year-old) multi-ethnic subjects who died of non-cardiovascular causes.

David M. Herrington, M.D., MHS, professor of Cardiology, and principal investigator for this national collaboration, says the aim is to create a detailed molecular characterization of arterial tissue with the purpose of identifying the genetic variants associated with premature cardiovascular disease. "By using state-of-the-art molecular and analytic methods, we will be able to determine the genomic and proteomic architecture of premature atherosclerosis," Herrington said. "This will add fundamentally new knowledge about the link between the genome and the proteome in the artery wall."


'/>"/>

Contact: Paula Faria
pfaria@wakehealth.edu
336-716-1279
Wake Forest Baptist Medical Center
Source:Eurekalert

Page: 1

Related medicine news :

1. UCF nanoscientist receives $2 million NIH award
2. Saving brains in developing countries: $11.8 million for innovative ideas worldwide
3. Funding for neglected global diseases research at UBC exceeds $20 million
4. Cedars-Sinai Heart Institute awarded $1.3 million to study cardiac stem cells
5. Millions of Americans Have Uncontrolled High Blood Pressure: CDC
6. Weill Cornell awarded $1.8 million for translational blood cancer research
7. UTMB receives $1.2 million to provide HPV vaccine
8. Johns Hopkins Armstrong Institute receives $8.9 million patient safety grant
9. Germany launches a €16 million epigenome program
10. Fit Brains, online portfolio of cognitive games, reaches milestone of 75 million brain scores
11. NIH awards $7.8 million for innovative HIV vaccine approaches
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... Four hospitals affiliated with the ... latest ranking of the country’s best hospitals by ... today and slated for publication in August, the U.S. ... (AGH), Forbes Hospital, Saint Vincent Hospital and West Penn ... specialties. , “There is no higher priority ...
(Date:7/23/2014)... Kathleen Doheny HealthDay Reporter ... surgery appears to have an additional side benefit -- ... to a new study. The study found that ... reported having incontinence prior to the procedure. After surgery, ... improved or disappeared, said study researcher Dr. Leslee Subak, ...
(Date:7/23/2014)... News) -- For patients infected with both HIV and ... both viruses, a small study suggests. Researchers said ... for people with the two diseases. "The ... an important role in the management of individuals with ... Kenneth Sherman, a professor of medicine at the University ...
(Date:7/23/2014)... BOSTON In a massive effort to catalog ... researchers at Dana-Farber Cancer Institute, have identified four ... other molecular abnormalities. They say the new classification ... therapies for the third-leading cancer killer worldwide. , ... of The Cancer Genome Atlas Research Network said ...
(Date:7/23/2014)... focused on the regions of the coding genome (exons) ... amino acids thus proteins. But just before each gene, ... the expression and activity of the adjacent gene. Until ... such DNA fragment in tumor development. , An ... with the group of Manel Esteller, Director of Epigenetics ...
Breaking Medicine News(10 mins):Health News:Four Allegheny Health Network Hospitals Named High Performers by U.S. News 2Health News:Four Allegheny Health Network Hospitals Named High Performers by U.S. News 3Health News:Weight Loss Surgery May Help Ease Urinary Incontinence 2Health News:Weight Loss Surgery May Help Ease Urinary Incontinence 3Health News:HIV Meds May Also Help Control Hepatitis C, Study Finds 2Health News:New view of stomach cancer could hasten better therapies 2Health News:New view of stomach cancer could hasten better therapies 3
... 10 Amedica Corporation, an,orthopedic implants company focused ... paper it presented on the in-vitro,testing and evaluation ... arthroplasty won the HAP Paul Award from the ... HAP Paul Award, which,was presented to Amedica at ...
... Shows Majority of Americans Would Like to See the United States ... ... a national bipartisan poll,commissioned by the US Coalition for Child Survival, ... cause of,child deaths in the world,s poorest countries. In reality, pneumonia,diarrhea, ...
... its 60th anniversary, the American Association for Cancer ... health disparities and minority cancer education. , AACEs ... Sheraton Birmingham Hotel, 2101 Richard Arrington Jr. Boulevard ... Minority and Underserved Populations. , The AACE meeting ...
... Ala., Oct. 10 Major financial implications are,at ... accurately record,the health conditions of patients that are ... the Centers for Medicare and Medicaid,Services (CMS). ... Group (DRG),assignment, including new methods for identifying patients ...
... 10 The American Medical,Student Association (AMSA), ... announced that a coalition representing the,majority of ... to pass the National Health Service Corps ... of 2007 (H.R. 2915). The NHSC ...
... YORK, Oct. 10 Buck Consultants, an ACS ... and benefits consulting firms,today announced the results of ... Buck,s study, "WORKING WELL: A Global Survey of ... 555 organizations,representing approximately 7 million employees. Such ...
Cached Medicine News:Health News:Amedica's Silicon Nitride Ceramic Bearing Technology Receives Prestigious HAP Paul Award for Use in Total Hip Arthroplasty 2Health News:Sixty Percent of Americans Cannot Name Top Killers of Kids 2Health News:Sixty Percent of Americans Cannot Name Top Killers of Kids 3Health News:US, European cancer educators gather in Alabama for meeting 2Health News:Use of Technology to Document Comorbid Conditions May Improve Reimbursement, Increase Documentation Accuracy Study Confirms 2Health News:Use of Technology to Document Comorbid Conditions May Improve Reimbursement, Increase Documentation Accuracy Study Confirms 3Health News:Coalition Urges Congress to Increase Funding for National Health Service Corps 2Health News:Coalition Urges Congress to Increase Funding for National Health Service Corps 3Health News:Buck Consultants Reports Wellness Programs Are Truly Global; Objectives Vary by Region 2Health News:Buck Consultants Reports Wellness Programs Are Truly Global; Objectives Vary by Region 3Health News:Buck Consultants Reports Wellness Programs Are Truly Global; Objectives Vary by Region 4
(Date:7/23/2014)... ROCHESTER, N.Y. , July 23, 2014 ... VSCP ), a leading provider of clinical trial ... , 48, has been named president and chief executive ... of Directors in August 2013 and has held the ... October 25, 2013. Dr. Charles E. ...
(Date:7/23/2014)... 23, 2014 Research and Markets ... in Consumer Healthcare by Application, Sensor Type & by ... 2020" report to their offering. ... an increasing momentum for consumer healthcare monitoring and sensing ... consumer healthcare will lessen the healthcare cost of the ...
(Date:7/23/2014)... MOUNTAIN VIEW, Calif. , July 23, ... in translational preclinical research, today unveiled their new logo ... the transformation of Surpass, corporate culture to one where ... customers. This press release comes on the heels of ... added to the Silicon Valley Team:  David Craig, a ...
Breaking Medicine Technology:Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 2Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 3Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 4Sensor Market in Consumer Healthcare (Patient Monitoring, Therapeutic, Handheld and Homecare, & Fitness and wellness) - Analysis & Forecast to to 2013 - 2020 2Sensor Market in Consumer Healthcare (Patient Monitoring, Therapeutic, Handheld and Homecare, & Fitness and wellness) - Analysis & Forecast to to 2013 - 2020 3SURPASS Launches New Company Logo and Corporate Website, Symbolizing Transformation of Company Culture to Meet the Changing Needs of Clients in the Life Science Community Today. 2SURPASS Launches New Company Logo and Corporate Website, Symbolizing Transformation of Company Culture to Meet the Changing Needs of Clients in the Life Science Community Today. 3
... Sept. 30, 2011 Haemonetics Corporation (NYSE: ... quarter of its 2012 fiscal year on October 31, ... hold a webcast to discuss and answer questions about ... 31, 2011. Webcast Link: http://phx.corporate-ir.net/phoenix.zhtml?p=irol-eventDetails&c=72118&eventID=4204617 ...
... Sept. 29, 2011 Boston Scientific Corporation (NYSE: ... ( NE ural C ardiac T her A ... a prospective, randomized, international clinical feasibility study designed to assess ... heart failure patients.  The study will evaluate 96 patients with ...
Cached Medicine Technology:Boston Scientific Begins Enrollment in NECTAR-HF Clinical Trial 2Boston Scientific Begins Enrollment in NECTAR-HF Clinical Trial 3Boston Scientific Begins Enrollment in NECTAR-HF Clinical Trial 4
... seats and large backrests with lumbar support ... and casters and glides. • Choose the ... variety of environments including: industry, education, laboratory, ... office. • With cast aluminum base • ...
... concave seats and large backrests with ... seats, backrests, armrests, and casters and ... for top performance in a variety ... clean room, static control, health care ...
... ergonomic chairs with concave seats and ... Select options like seats, backrests, armrests, ... the BE Series for top performance ... industry, education, laboratory, clean room, static ...
... seats and large backrests with lumbar support ... and casters and glides. • Choose the ... variety of environments including: industry, education, laboratory, ... office. • With cast aluminum base • ...
Medicine Products: