Navigation Links
$2.5 million Defense Department grant funds gene therapy study for Lou Gehrig's disease
Date:4/1/2014

tory failure when the diaphragm muscles become incapacitated," said Svendsen, who has studied ALS for more than a decade and whose team will perform the leg muscle studies while Suzuki's group conducts the respiratory muscle experiments.

The Department of Defense grant will support all animal studies needed to take these experiments from the bench side to the bedside leading to the filing of an Investigational New Drug application with the Food and Drug Administration. The IND process is a regulatory step between preclinical study and human clinical trials. If approved, Cedars-Sinai's large ALS Program, led by Robert H. Baloh, MD, PhD, has a clinical trials group in place to move this research into the clinic.

"Muscle is much more readily accessible for treatment and biopsy than brain tissue or the spinal cord, which makes this strategy very appealing," Svendsen said. "Our previous findings provide strong evidence that the viral vector can transfer the GDNF protein into muscle, and we have shown that GDNF delivered to muscle may slow disease progression. We appreciate the Department of Defense's interest and funding, which will make it possible for us to further this exciting research."

Svendsen's research group in 2012 received a $17.8 million grant from the California Institute for Regenerative Medicine to develop stem cell treatments for patients with ALS based on injections of stem cells releasing GDNF into the spinal cord.


'/>"/>

Contact: Sandy Van
sandy@prpacific.com
808-526-1708
Cedars-Sinai Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Marriage linked to lower heart risks in study of 3.5+ million adults
2. Scripps Florida scientist awarded $2.3 million to study dengue fever and related viruses
3. The Brain & Behavior Research Foundation awards $4 million in NARSAD Grants
4. Einstein helps establish $28 million consortium to find ebola treatment
5. Stroke in children will be focus of $3 million grant
6. UTMB receives $3.2 million to continue collaborative research on cancer in Texas
7. NCI recommends the Wistar Institute receive $14.9 million support grant renewal
8. Cancer treatment, artery repair are goals of $3 million in NIH grants
9. UC Irvine stem cell researchers awarded $1.54 million in state funding
10. UCSF receives $50 million gift
11. UCSF team wins $2.7 million grant for innovative project to reduce premature births
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/27/2014)... (PRWEB) November 27, 2014 In order to ... from Sharpes, Fla., designed an easy way to avoid touching ... , He then created a prototype of the patent-pending Toilet ... lower a toilet seat and/or lid in a more sanitary ... the spread of germs. Overall, it promotes good hygiene and ...
(Date:11/27/2014)... November 27, 2014 The founders of VIM ... comfortable and high functioning compression socks, are proud to announce ... use an innovative Gradient Pressure (TM) knitting technology that is ... VIM & VIGR’s commitment to adding flair and style to ... functional recently caught the eye of a writer at ...
(Date:11/27/2014)... Jeffrey Carlini has practiced public ... area providing audits, reviews, compilations, tax preparation, business ... varying size across numerous industries. Jeff has worked ... of their accounting and tax needs. , Jeff ... Program. When asking Mr. Carlini about his recent ...
(Date:11/27/2014)... Vegas, NV (PRWEB) November 27, 2014 ... 2014 shopping season has officially launched, Emassagechair.com ... and Cyber Monday Discount Event. , Negotiating on ... relationships with top massage chair brands, Emassagechair.com has generated ... their best deals and biggest discounts yet. , Shoppers ...
(Date:11/27/2014)... York, New York (PRWEB) November 27, 2014 ... of individuals who were allegedly injured by the medication ... where a federal litigation is looking ahead to a ... , According to a Scheduling Order issued earlier this ... place on December 16th at 10:00 a.m. Items likely ...
Breaking Medicine News(10 mins):Health News:VIM & VIGR Announces Launch of Men’s Line of Compression Socks 2Health News:Jeffrey Carlini becomes Intuit Proadvisor and receives QuickBooks certification 2Health News:Emassagechair.com is Excited to Announce Their Biggest Discount Event of the Year, Starting the Day After Thanksgiving and Lasting Through The Holiday Weekend. 2Health News:Emassagechair.com is Excited to Announce Their Biggest Discount Event of the Year, Starting the Day After Thanksgiving and Lasting Through The Holiday Weekend. 3Health News:Emassagechair.com is Excited to Announce Their Biggest Discount Event of the Year, Starting the Day After Thanksgiving and Lasting Through The Holiday Weekend. 4Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 2Health News:Federal Litigation Presiding over Tylenol Lawsuits Looks Ahead to Status Conference in December, Bernstein Liebhard LLP Reports 3
... type 1 a rare disease in which tumors grow ... by crosstalk between cells in the nerves and cells in ... National Institutes of Health (NIH) and the Department of Defense ... treating certain kinds of blood cancer curbs tumor growth in ...
... One errant cough or unexpected,sneeze and the workplace ... As the flu season approaches, HR managers prepare to,deal ... estimates that the cost of influenza to the U.S. ... can range from $71 billion,to $167 billion a year., ...
... Living,Inc. (NYSE: SRZ ) today announced that it ... 7, 2008, at 9:00 a.m. ET to discuss the,financial ... executive,officer (effective November 1, 2008), Richard Nadeau, chief financial,officer, ... call., The call-in number for the conference call ...
... Institute of Health and Nutrition, Latino Nutrition Coalition are ... ... Inc. (GMI), today,announced the launch of a unique, three-year, grassroots program ... nutritious food as part of their daily routine. Called Mente,Sana en ...
... Action Network, American,Heart Association, American Lung Association, American ... Oct. 30 Demonstrating again that,it is not ... Philip Morris,is launching an aggressive new campaign to ... campaign is built around a new look for ...
... LLC formally launched a,refreshed website ( ... and,potential customers on October 28, 2008. The ... target-market, including temporary,nurse staffing agencies, medical transcription ... healthcare vendors., Some of the site,s ...
Cached Medicine News:Health News:Researchers identify mechanism, possible drug treatment for tumors in neurofibromatosis 2Health News:Researchers identify mechanism, possible drug treatment for tumors in neurofibromatosis 3Health News:Going 'Green' May Mean Fewer Colds This Season 2Health News:Going 'Green' May Mean Fewer Colds This Season 3Health News:Sunrise to Host Conference Call and Webcast to Discuss the Company's Financial Results for the Third Quarter 2008 2Health News:General Mills, Inc. Launches One-Of-A-Kind Grassroots Health and Nutrition Initiative Designed to Help Hispanic Families Eat Better 2Health News:General Mills, Inc. Launches One-Of-A-Kind Grassroots Health and Nutrition Initiative Designed to Help Hispanic Families Eat Better 3Health News:Deadly in Pink: Philip Morris' New Look for Virginia Slims Cigarettes Shows Contempt for Women's Health 2Health News:Deadly in Pink: Philip Morris' New Look for Virginia Slims Cigarettes Shows Contempt for Women's Health 3Health News:PRN Funding Refreshes Website Experience 2
(Date:11/27/2014)... -- - New Solution That Makes JINS ... JIN Co., Ltd. will launch JINS MEME "ACADEMIC PACK" in ... or $5,000 (without tax /including two pairs of JINS MEME ... dedicated solution of "JINS MEME" to academic researchers, and it ... by electrooculography and six-axis sensors without API. (*Physiological data that ...
(Date:11/26/2014)... 26, 2014  Thoratec Corporation (NASDAQ: THOR ... therapies to save, support and restore failing hearts, said ... conferences. On Tuesday, December 2, the company ... Jaffray Healthcare Conference.  D. Keith Grossman , President ... the company beginning at 11:30 a.m., Eastern Standard Time ...
(Date:11/26/2014)...   Royal Philips (NYSE: ... of its portfolio of diagnostic X-ray solutions ... , ProGrade and PrimaryDiagnost[ii]. With new releases of ... U.S., and availability of all these solutions in ... innovative solutions designed to meet the needs and ...
Breaking Medicine Technology:JIN to Launch JINS MEME ACADEMIC PACK in Late April 2015 2JIN to Launch JINS MEME ACADEMIC PACK in Late April 2015 3Thoratec Announces Presentations At Investor Conferences For December 2014 2Philips expands global reach of diagnostic X-Ray solutions 2Philips expands global reach of diagnostic X-Ray solutions 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: