Navigation Links
$12 million NIH grant to study acute lung injury
Date:7/29/2011

Researchers at the University of Illinois at Chicago College of Medicine have been awarded more than $11.7 million to study the pathology of severe lung injury.

The study, part of a multi-pronged investigation into acute lung injury, or ALI, is funded by the National Heart, Lung and Blood Institute, one of the National Institutes of Health.

ALI and its even more severe form, acute respiratory distress syndrome, result from pulmonary edema -- leaky blood vessels -- and inflammation. Direct lung injury from infection or indirect injury from trauma, sepsis, pancreatitis, transfusions, radiation or drug overdose can trigger ALI. It is fatal almost 40 percent of the time.

"We are now ready to address the very important, clinically relevant aspects of the pathobiology of ALI and investigate novel therapeutic approaches," said Natarajan, program director and professor of pharmacology and medicine at UIC, who has been studying ALI for 20 years. Natarajan also co-directs the Institute for Personalized Respiratory Medicine at UIC with Dr. Joe G.N. "Skip" Garcia, University of Illinois vice president for health affairs, UIC vice chancellor for research and Earl M. Bane Professor of Medicine.

The NIH Program Project Grant is an interdisciplinary investigation of a bio-active lipid called sphingosine-1-phosophate, or S1P, and its receptors and their role in lung cell signaling, inflammation and injury caused by sepsis or radiation.

One project, led by Natarajan, will use animal and cell-culture models to investigate how S1P is generated inside cells and how it exerts a protective effect in ALI -- an effect which Garcia, Natarajan and their collaborators had demonstrated previously in animal models of ALI.

A second project, headed by Garcia, will investigate the role of S1P receptors in ALI.

"Dr. Garcia brings cutting-edge expertise in genomics, genetics and clinical medicine to the project," Natarajan said, "a
'/>"/>

Contact: Jeanne Galatzer-Levy
jgala@uic.edu
312-996-1583
University of Illinois at Chicago
Source:Eurekalert

Page: 1 2

Related medicine news :

1. WU studies obesity, cancer link with $9.2 million grant
2. NIH awards WSU researcher $1.7 million to study non-alcoholic fatty liver disease
3. Harvard School of Public Health receives $14.1 million to test childbirth checklist
4. INFORMS study: OR models of hepatitis B prove decisive in treating millions in US, China
5. Penn receives $10 million to create center for orphan disease research and therapy
6. Study: Doctors differ in how best to care for Americas 12 million cancer survivors
7. BUSM/BMC researchers awarded $3.5 million grant from the NIDA
8. Lifestyle Changes Might Prevent Millions of Cases of Alzheimers
9. Columbia University Medical Center receives $38.9 million to help translate science into treatment
10. New therapy provides hope for millions of people suffering from bowel incontinence
11. UCSF receives $112 million to help translate science into cures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... By Maureen Salamon ... -- A crucial part of conventional in vitro fertilization (IVF) ... can instead take place in a device inside the vagina, ... Colombia contend that the device, called an INVOcell, might sharply ... could also make the technology more accessible to those who ...
(Date:10/22/2014)... HealthDay Reporter TUESDAY, Oct. 21, 2014 ... while working for NBC News in Liberia has cleared ... unit at Nebraska Medical Center in Omaha, where he had been ... A blood test confirmed by the U.S. Centers for Disease Control ... Providence, R.I., NBC News reported Tuesday night. "Recovering ...
(Date:10/20/2014)... October 20, 2014 Allegheny General Hospital’s ... that enables physicians to repair a damaged mitral valve ... MitraClip system, developed by Abbott Vascular , ... progressive and life-threatening condition in which the heart’s mitral ... flow backward from the heart’s left ventricle into the ...
(Date:10/20/2014)... 2014 Women’s health specialist, Dr. Amber ... Gynecology of Columbus, Inc., A Division of MaternOhio Clinical ... more than 100,000 patients annually. Dr. Murphy will provide ... stages of a women’s life. She is accepting new ... Westerville and Dublin. , Dr. Murphy offers a wide ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 Zereana Jess-Huff, a ... Mrs. Maryland 2014 on a platform to think outside the ... and uses her position to raise awareness about women’s other ... for breast cancer. You say the color pink and everybody ... know for a fact that it has not been won ...
Breaking Medicine News(10 mins):Health News:Experimental Infertility Treatment Seems Effective, Cheaper 2Health News:Experimental Infertility Treatment Seems Effective, Cheaper 3Health News:Experimental Infertility Treatment Seems Effective, Cheaper 4Health News:U.S. Cameraman Treated for Ebola 'Free' of the Virus 2Health News:U.S. Cameraman Treated for Ebola 'Free' of the Virus 3Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 2Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 3Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 2Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 3Health News:Ovarian Cancer Survivor Mrs. Maryland Urges Media to Think Outside the Bra 2Health News:Ovarian Cancer Survivor Mrs. Maryland Urges Media to Think Outside the Bra 3
... of Cost-Effective High-Quality Home Infusion Can be ... WASHINGTON, March 5 Patients on Medicare ... Johnny Isakson (R-GA) and Representative Eliot L. ... a flaw in the Medicare program which ...
... YORK (March 5, 2009) -- Two highly lethal viruses that ... established drug used to prevent and treat malaria, according to ... Medical College in the Journal of Virology . Due ... advance of the first April print issue. , The two ...
... of Nutrition and Physical Activity at the Indiana State ... GoTrybe.com to provide Indiana kids and teens with a ... fun. Young Hoosiers can enjoy FREE memberships to the ... www.GoTrybeIN.com . A 2007 Youth Risk Behavior Survey showed ...
... the commercial printing superstore was honored for ecommerce expertise when President ... the online version of the highly respected Entrepreneur magazine. , ... ... selected Mr. Del Chiaro for the interview based on his proven ...
... on annual listOAKLAND, Calif., March 5 ... been recognized by DiversityMBA ... was ranked No. 1 in the publication,s fourth annual ... Diverse Managers to Work," which will hit newsstands in ...
... don,t offer emergency contraception pills to adolescents who ... because of misinformation about how the medicine works, ... of Philadelphia. Improved physician education may increase prescription ... said. Researchers surveyed 291 members of the ...
Cached Medicine News:Health News:Patients, Senate, House Members Identify Significant Medicare Savings While Increasing Quality of Patient Care 2Health News:Patients, Senate, House Members Identify Significant Medicare Savings While Increasing Quality of Patient Care 3Health News:Drug blocks 2 of world's deadliest emerging viruses 2Health News:Drug blocks 2 of world's deadliest emerging viruses 3Health News:GoTrybe.com Launched in Indiana to Promote Children's Health 2Health News:My1Stop.com President Michael Del Chiaro Interviewed by Entrepreneur.com for ecommerce Expertise 2Health News:Kaiser Permanente Recognized as Best Place for Diverse Managers 2Health News:Kaiser Permanente Recognized as Best Place for Diverse Managers 3Health News:Research Says Better Physician Education Would Improve Hospital Prescription of Emergency Birth Control to Teens 2Health News:Research Says Better Physician Education Would Improve Hospital Prescription of Emergency Birth Control to Teens 3
(Date:10/22/2014)... Oct. 21, 2014   BioNano Genomics , ... genomics research centers to purchase an Irys™ System ... National Cancer Institute (NCI), NIH Intramural Sequencing Center (NISC) ... Irys, obtaining a comprehensive view of a genome ... (NGS) does not deliver the scalability or reliability ...
(Date:10/22/2014)... 2014 InVivo Therapeutics Holdings Corp. (OTCQB: NVIV) ... revolutionizing spinal cord injury (SCI) treatment with their novel ... in tissue regrowth in the spinal cord area when ... FDA approved polymer, the scaffold ultimately breaks down to ... human body. NVIV has recently attracted significant investor attention ...
(Date:10/22/2014)... Calif. , Oct. 22, 2014  AcelRx ... announced that results from the  IAP310 study have ... Medicine (RAPM), a peer-reviewed journal with broad, ... 3 trial evaluating the safety and efficacy of ... tablet system (SSTS), for the treatment of post-operative ...
Breaking Medicine Technology:BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 2BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 3InVivo Therapeutics Analyst Coverage Initiated: Analyst Report by BrokerBank Securities, Inc. 2InVivo Therapeutics Analyst Coverage Initiated: Analyst Report by BrokerBank Securities, Inc. 3AcelRx Announces Publication of Zalviso Phase 3 Abdominal Trial Results 2
Hudson Drill hand drill....
Hudson Brace, snap lock chuck....
Binocular operation microscope with innovative mechanism for smooth operation....
... has pioneered the development of ... system, an innovative solution that ... efficient and less invasive. The ... the OME-7000 surgical microscope, the ...
Medicine Products: