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$100 million gift launches Sanford Stem Cell Clinical Center
Date:11/4/2013

deal of the progress in stem cell research has occurred at UC San Diego School of Medicine. For example:

Catriona H.M. Jamieson, MD, PhD, associate professor of medicine at UC San Diego School of Medicine and director of the UC San Diego Moores Cancer Center stem cell program, and colleagues are conducting or planning trials for several stem cell-derived treatments of leukemia and other blood diseases that have shown encouraging results in animal models and human clinical trials.

Mark H. Tuszynski, MD, PhD, professor in the UC San Diego Department of Neurosciences and director of the UC San Diego Translational Neuroscience Institute, investigates both the slowly evolving neurological damage of Alzheimer's disease and the sudden, catastrophic consequences of traumatic spinal cord injuries. In the latter work, Tuszynski and colleagues recently reported using introduced neural stem cells to regenerate axon growth at the site of severe spinal cord injuries in rats, restoring some movement. Goldstein's lab has created, for the first time, stem cell-derived, in-vitro models of sporadic and hereditary Alzheimer's disease using induced pluripotent stem cells from patients with AD. These functional Alzheimer's neurons in a dish promise to be an unprecedented tool for developing and testing drugs to treat the dreaded neurodegenerative disorder.

The Sanford Stem Cell Clinical Center will advance these and other stem cell projects in crucial ways, said Goldstein, accelerating their movement into clinical trials with patients. The Center will deepen the connection with stem cell research partners in San Diego, allowing them to collaborate with one of the country's leading academic medical centers. It will establish the best standards in stem cell testing, safety and efficacy. It will effectively tackle the necessary regulatory requirements. All of these efforts, Goldstein said, are critical to speeding experimental therapies to use by patients.

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Contact: Debra Kain
ddkain@ucsd.edu
619-543-6163
University of California - San Diego
Source:Eurekalert  

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