Navigation Links
$1.9 million grant to help UCF find multiple sclerosis 'nerve-ana'

A National Institutes of Health grant will help University of Central Florida researchers explore new ways to potentially reverse the damage caused by multiple sclerosis and other neurological disorders.

Stephen Lambert, an associate professor in the College of Medicine and a member of UCF's Hybrid Systems Laboratory, has received $428,000, the first installment of a four-year, $1.9 million project. His team will study the breakdown of myelin, a substance that coats and protects nerves inside the brain and spinal cord, enabling electrical signals to reach distant nerve cells and muscles.

About 400,000 Americans and about 2.5 million people worldwide suffer from MS, according to the National Multiple Sclerosis Society. The drugs that are available now focus mainly on controlling the inflammatory nature of the diseases to limit the development of neuronal damage. They do not reverse the damage caused by the diseases.

"The process of myelination is extremely complex. By reproducing these complex phenomena in our laboratories, we can learn more about what causes debilitating diseases that affect so many people around the world," Lambert said. "We hope our research will ultimately lead to new drugs that reverse the damage caused by these diseases and help patients lead longer, healthier lives."

Most of the research will take place in the Hybrid Systems Lab in UCF's NanoScience Technology Center. At the center, a research team led by UCF bioengineer James Hickman showed for the first time last year that specialized myelin coating could be produced in the lab environment without the use of any type of growth serum.

The finding is significant because it allows researchers to more clearly study the causes of breaks in myelin and also the impact of proposed chemical treatments. Both could potentially lead to a greater understanding of the causes of neurological disorders such as MS and diabetes-induced peripheral neuropathy.

Hickman's previous work focused on cells in the peripheral nervous system and the nerves that connect the body's limbs and organs to the brain. The new research will, for the first time, explore the breakdown of myelin in the areas inside the brain and the spinal cord using nanotechnology tools.

"The application of the high-tech tools developed in my lab at the NanoScience Center to this complex problem brings us that much closer to developing new drugs and, at some stage, a cure for diseases such as MS," Hickman said.


Contact: Barb Abney
University of Central Florida

Related medicine news :

1. Kaiser Permanente Gives $5 Million to Childrens Healthcare of Atlanta
2. RadioShack Customers Donate $1.3 Million to LIVESTRONG
3. Michael J. Fox Foundation Awards $2.8 Million to Drive Development of Parkinsons Disease Biomarker Pipeline
4. Human Rights Denied: Obama Leaves 75 Million Children Behind
5. NVHR: Administrations 2011 Budget Proposal Shortchanges Five Million Americans Afflicted with Chronic Viral Hepatitis
6. State $200 Million Behind in Payments to Agencies Providing Care to Thousands of Older Illinoisans
7. Prominent Beverly Hills Law Firm Awarded $16.5 Million Medical Malpractice Jury Verdict
8. Esperanza Health Center Receives $6.5 Million in Stimulus Funds
9. Fitch, Standard & Poor's Upgrade Scripps Health to AA-; Scripps to Issue $220 Million in Hospital Revenue Bonds
10. millionants productions Launches and is “Making a Scene”
11. MAP International Provides $10 Million in Essential Medicines and Medical Supplies to Haiti Relief
Post Your Comments:
(Date:11/25/2015)... ... 2015 , ... Beddit® has launched a new Android app for ... features a more intuitive SleepScore™ that rates sleep quality on a 100-point scale and ... created by a proprietary algorithm. Beddit analyzes the data to provide an easy to ...
(Date:11/25/2015)... ... November 25, 2015 , ... ... for people struggling with eating disorders as a result of the $20,000 raised ... event, held at Fox Run Golf Club in Eureka, will help individuals who ...
(Date:11/25/2015)... ... 2015 , ... Many people know of the common symptoms of low thyroid ... skin. But many people who find their cholesterol levels and weight are creeping up ... especially if they don’t have any of the other symptoms. , Thyroid hormone plays ...
(Date:11/24/2015)... Florida (PRWEB) , ... November 25, 2015 , ... ... planning and monitoring. Their Care Plan software creates an agreement between the ... patient care plan, including financial, scheduling, monitoring, notification, and projections. Click ...
(Date:11/24/2015)... ... ... Charitable giving is at its peak during the holidays. In fact, nearly ... year totalling over $358 billion in 2014. With more than 1.5 million U.S. ... who want to “give back” during the holidays. , “With so many charities to ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... Calif. , Nov. 24, 2015 /PRNewswire/ ... leader in non-invasive genetic testing and the ... that it will present at the 27 ... York on Wednesday, December 2, 2015 at 1:00 p.m. ET.  Matthew Rabinowitz, ... Company,s financial results, business activities and financial ...
(Date:11/24/2015)... November 2015 Avery Biomedical Devices ... ist erfreut, die Berufung von Anders Jonzon, ... zu können.   ... Foto -   ... 1984-1986 war er Fellow des Cardiovascular Institute ...
(Date:11/24/2015)... 2015   HeartWare International, Inc . (NASDAQ: ... support technologies that are revolutionizing the treatment of advanced ... Officer Doug Godshall is scheduled to present ... Conference on December 1, 2015 at 3:00 p.m. ET.  ... New York . ...
Breaking Medicine Technology: