Navigation Links
$1.8 million grant to support research on impact of social stress
Date:7/31/2013

ATLANTADr. Kim Huhman, a researcher in the Center for Behavioral Neuroscience (CBN) at Georgia State University, has received a federal five-year, $1.8 million grant for research that may lead to improved strategies for treating and preventing mental health problems associated with exposure to social stress.

The grant from the National Institute of Mental Health will aid Huhman's study of how exposure to social stress causes changes in brain and behavior. Most humans experience social stress as the result of exposure to bullying, abuse or conflict in school, home and the workplace.

"These social stressors have been shown to cause or contribute to a wide variety of illnesses, including heart disease, depression and anxiety disorders," said Huhman, who, in addition to her role as a CBN researcher, is a professor in Georgia State's Neuroscience Institute and Department of Psychology. "The current treatment strategies for stress-related illnesses such as depression and anxiety disorders are inadequate for a significant number of patients. We hope to improve these outcomes significantly."

To study how social stress leads to changes in the brain and behavior, Huhman developed an animal model of social stress in hamsters. After being defeated even a single time by a larger, more aggressive opponent, hamsters exhibit pronounced social avoidance even when interacting with much smaller, non-aggressive individuals. The Huhman lab calls this pronounced change in behavior "conditioned defeat."

Conditioned defeat occurs even though hamsters are not injured during the initial defeat. The social stress is relatively mild and mainly psychological. Defeated hamsters (as well as rats and mice) also show anxiety- and depression-like changes in behavior such as alterations in feeding, sleep and startle responses, and decreases in interest in previously preferred stimuli. By studying how social stress causes conditioned defeat, Huhman aims to improve understanding of how, from a neurobiological standpoint, psychological stress has deleterious effects on physical and psychological health.

Conditioned defeat offers a unique opportunity to explore how multiple brain circuits that mediate fear/anxiety, emotional learning, social behavior and motivation interact to control complex social behavior and to "shift" or "switch" individuals among stable behavioral states. The nature of such switches and how they can have such a dramatic impact on future behavior is a fundamental unanswered question in behavioral neuroscience.

According to Huhman, "because these brain circuits are largely the same in rodents and humans, the data generated by this project will have important implications for the potential therapeutic usefulness of drugs, currently in the testing phase, to alter behavioral responses to social stress".


'/>"/>

Contact: Natasha De Veauuse Brown
ndeveauusebrown@gsu.edu
404-413-3602
Georgia State University
Source:Eurekalert

Related medicine news :

1. NIH awards $20 million over 5 years to train next generation of global health researchers
2. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
3. David H. Koch donates $10 million to Mount Sinais Jaffe Food Allergy Institute
4. $9 million grant awarded to UH to study, treat learning disabilities
5. New report shows 15 million babies born too soon every year
6. Southeast program to fight diabetes awarded nearly $10 million by HHS
7. OHSU study: Misdiagnosis of MS is costing health system millions per year
8. Enzyme corrects more than 1 million faults in DNA replication
9. 53 million Americans might have diabetes by 2025, according to a new study in Population Health Management
10. Asthma Cases Continue to Rise in U.S., Affecting Millions
11. UC San Diego Superfund Research Program receives $15 million grant renewal
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar ... M.D from the David Geffen School of Medicine at UCLA. He trained in Internal ... complete his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had ...
(Date:6/25/2016)... ... ... On Friday, June 10, Van Mitchell, Secretary of the Maryland Department of Health and ... their exemplary accomplishments in worksite health promotion. , The Wellness at Work Awards took ... the BWI Marriott in Linthicum Heights. iHire was one of 42 businesses to receive ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... A ... procedures that most people are unfamiliar with. The article goes on to state that ... but also many of these less common operations such as calf and cheek reduction. ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort ... holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain ... Disease (SCD) is a disorder of the red blood cells, which can cause episodes ...
(Date:6/24/2016)... Texas (PRWEB) , ... June 24, 2016 , ... ... International Conference and Scientific Sessions in Dallas that it will receive two significant ... of the grants came as PHA marked its 25th anniversary by recognizing patients, ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016   Bay Area Lyme ... Dean Center for Tick Borne Illness , ... Rehabilitation, MIT Hacking Medicine, University of California, Berkeley, ... announced the five finalists of Lyme Innovation ... More than 100 scientists, clinicians, researchers, entrepreneurs, and ...
(Date:6/24/2016)... , June 24, 2016  American Respiratory Labs (ARL), a ... now able to perform sophisticated lung assessments in patients, homes, thanks ... Inc. Patients are no longer limited to having ... PRO ® , ARL patients like Jeanne R. of ... the comfort of her own home. ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, a ... invasive and more durable cerebrospinal fluid treatments, today ... The Series-A funding is led by Innova Memphis, ... and other private investors.  Arkis, new financing will ... and the market release of its in-licensed Endexo® ...
Breaking Medicine Technology: