Navigation Links
$1.8 Million Grant to Support Research on Impact of Social Stress
Date:7/31/2013

Atlanta, GA (PRWEB) August 01, 2013

Dr. Kim Huhman, a researcher in the Center for Behavioral Neuroscience (CBN) at Georgia State University, has received a federal five-year, $1.8 million grant for research that may lead to improved strategies for treating and preventing mental health problems associated with exposure to social stress.

The grant from the National Institute of Mental Health will aid Huhman’s study of how exposure to social stress causes changes in brain and behavior. Most humans experience social stress as the result of exposure to bullying, abuse or conflict in school, home and the workplace.

“These social stressors have been shown to cause or contribute to a wide variety of illnesses, including heart disease, depression and anxiety disorders,” said Huhman, who, in addition to her role as a CBN researcher, is a professor in Georgia State’s Neuroscience Institute and Department of Psychology. “The current treatment strategies for stress-related illnesses such as depression and anxiety disorders are inadequate for a significant number of patients. We hope to improve these outcomes significantly.”

To study how social stress leads to changes in the brain and behavior, Huhman developed an animal model of social stress in hamsters. After being defeated even a single time by a larger, more aggressive opponent, hamsters exhibit pronounced social avoidance even when interacting with much smaller, non-aggressive individuals. The Huhman lab calls this pronounced change in behavior “conditioned defeat.”

Conditioned defeat occurs even though hamsters are not injured during the initial defeat. The social stress is relatively mild and mainly psychological. Defeated hamsters (as well as rats and mice) also show anxiety- and depression-like changes in behavior such as alterations in feeding, sleep and startle responses, and decreases in interest in previously preferred stimuli. By studying how social stress causes conditioned defeat, Huhman aims to improve understanding of how, from a neurobiological standpoint, psychological stress has deleterious effects on physical and psychological health.

Conditioned defeat offers a unique opportunity to explore how multiple brain circuits that mediate fear/anxiety, emotional learning, social behavior and motivation interact to control complex social behavior and to “shift” or “switch” individuals among stable behavioral states. The nature of such switches and how they can have such a dramatic impact on future behavior is a fundamental unanswered question in behavioral neuroscience.

According to Huhman, “because these brain circuits are largely the same in rodents and humans, the data generated by this project will have important implications for the potential therapeutic usefulness of drugs, currently in the testing phase, to alter behavioral responses to social stress.”

An abstract of the grant is available on the NIH’s Project RePORTER website, http://projectreporter.nih.gov.

For more information about Dr. Huhman and the research being conducted in her laboratory, visit http://neuroscience.gsu.edu/khuhman.html.

Read the full story at http://www.prweb.com/releases/2013/8/prweb10986399.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. NIH awards $20 million over 5 years to train next generation of global health researchers
2. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
3. David H. Koch donates $10 million to Mount Sinais Jaffe Food Allergy Institute
4. $9 million grant awarded to UH to study, treat learning disabilities
5. New report shows 15 million babies born too soon every year
6. Southeast program to fight diabetes awarded nearly $10 million by HHS
7. OHSU study: Misdiagnosis of MS is costing health system millions per year
8. Enzyme corrects more than 1 million faults in DNA replication
9. 53 million Americans might have diabetes by 2025, according to a new study in Population Health Management
10. Asthma Cases Continue to Rise in U.S., Affecting Millions
11. UC San Diego Superfund Research Program receives $15 million grant renewal
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2016)... ... May 25, 2016 , ... DKT International, ... the developing world, is pleased to release their 2015 global impact data. In ... pregnancies, almost 14,000 maternal deaths and 3.8 million unsafe abortions across 21 countries ...
(Date:5/25/2016)... ... May 25, 2016 , ... Conrad Siegel Actuaries, delivering ... and Prescription Drug survey , an employee benefits survey measuring how ... in December 2015, indicates that employers are turning to consumer directed health care ...
(Date:5/25/2016)... ... May 25, 2016 , ... "FCPX LUT Intense allows ... your footage," said Christina Austin - CEO of Pixel Film Studios. , With ... and easily add stylish color grades to their footage. A LUT is a Lookup ...
(Date:5/25/2016)... ... May 25, 2016 , ... HealthPostures ... will join America's leading engineers at the American Society of Safety Engineers Conference ... Congress Center. , Engineers, speakers and exhibitors from more than 40 countries ...
(Date:5/24/2016)... ... May 24, 2016 , ... BTC Media, ... blockchain event, Distributed: Health, to be held in Nashville, Tennessee on September 7, ... A 24-hour Hackathon preceding the event will host teams from around the world, ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... 2016 ReportsnReports.com adds "Chronic ... that provides an overview on therapeutic pipeline of ... stages, therapeutics assessment by drug target, mechanism of ... type, along with latest updates, and featured news ... involved in the therapeutic development for Chronic Cough ...
(Date:5/24/2016)...   , ... primären Endpunkte und demonstriert Ebenbürtigkeit bei der Gesamtreinigung ... plus guter , Reinigung des ...      (Logo: http://photos.prnewswire.com/prnh/20130829/633895-a ) , ... von der MORA-Studie der Phase III für NER1006 ...
(Date:5/24/2016)... Zealand , May 24, 2016 ... informatics solutions for the healthcare sector, has been named the ... Zealand Hi-Tech Awards 2016. Dr Bruce Davey ... acknowledgement for our team.  It,s really good to be recognised ... healthcare internationally. Our products are used in 35 countries around ...
Breaking Medicine Technology: