Navigation Links
$1.8 Million Grant to Support Research on Impact of Social Stress
Date:7/31/2013

Atlanta, GA (PRWEB) August 01, 2013

Dr. Kim Huhman, a researcher in the Center for Behavioral Neuroscience (CBN) at Georgia State University, has received a federal five-year, $1.8 million grant for research that may lead to improved strategies for treating and preventing mental health problems associated with exposure to social stress.

The grant from the National Institute of Mental Health will aid Huhman’s study of how exposure to social stress causes changes in brain and behavior. Most humans experience social stress as the result of exposure to bullying, abuse or conflict in school, home and the workplace.

“These social stressors have been shown to cause or contribute to a wide variety of illnesses, including heart disease, depression and anxiety disorders,” said Huhman, who, in addition to her role as a CBN researcher, is a professor in Georgia State’s Neuroscience Institute and Department of Psychology. “The current treatment strategies for stress-related illnesses such as depression and anxiety disorders are inadequate for a significant number of patients. We hope to improve these outcomes significantly.”

To study how social stress leads to changes in the brain and behavior, Huhman developed an animal model of social stress in hamsters. After being defeated even a single time by a larger, more aggressive opponent, hamsters exhibit pronounced social avoidance even when interacting with much smaller, non-aggressive individuals. The Huhman lab calls this pronounced change in behavior “conditioned defeat.”

Conditioned defeat occurs even though hamsters are not injured during the initial defeat. The social stress is relatively mild and mainly psychological. Defeated hamsters (as well as rats and mice) also show anxiety- and depression-like changes in behavior such as alterations in feeding, sleep and startle responses, and decreases in interest in previously preferred stimuli. By studying how social stress causes conditioned defeat, Huhman aims to improve understanding of how, from a neurobiological standpoint, psychological stress has deleterious effects on physical and psychological health.

Conditioned defeat offers a unique opportunity to explore how multiple brain circuits that mediate fear/anxiety, emotional learning, social behavior and motivation interact to control complex social behavior and to “shift” or “switch” individuals among stable behavioral states. The nature of such switches and how they can have such a dramatic impact on future behavior is a fundamental unanswered question in behavioral neuroscience.

According to Huhman, “because these brain circuits are largely the same in rodents and humans, the data generated by this project will have important implications for the potential therapeutic usefulness of drugs, currently in the testing phase, to alter behavioral responses to social stress.”

An abstract of the grant is available on the NIH’s Project RePORTER website, http://projectreporter.nih.gov.

For more information about Dr. Huhman and the research being conducted in her laboratory, visit http://neuroscience.gsu.edu/khuhman.html.

Read the full story at http://www.prweb.com/releases/2013/8/prweb10986399.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. NIH awards $20 million over 5 years to train next generation of global health researchers
2. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
3. David H. Koch donates $10 million to Mount Sinais Jaffe Food Allergy Institute
4. $9 million grant awarded to UH to study, treat learning disabilities
5. New report shows 15 million babies born too soon every year
6. Southeast program to fight diabetes awarded nearly $10 million by HHS
7. OHSU study: Misdiagnosis of MS is costing health system millions per year
8. Enzyme corrects more than 1 million faults in DNA replication
9. 53 million Americans might have diabetes by 2025, according to a new study in Population Health Management
10. Asthma Cases Continue to Rise in U.S., Affecting Millions
11. UC San Diego Superfund Research Program receives $15 million grant renewal
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... Oklahoma City, Oklahoma (PRWEB) , ... June 25, ... ... to helping both athletes and non-athletes recover from injury. Recently, he has implemented ... for the Oklahoma City area —Johnson is one of the first doctors to ...
(Date:6/24/2016)... Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... surgery procedures that most people are unfamiliar with. The article goes on to state ... procedures, but also many of these less common operations such as calf and cheek ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Marcy was in a crisis. Her son James, ... out at his family verbally and physically. , “When something upset him, he couldn’t control ... use it. He would throw rocks at my other children and say he was going ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda ... orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including ... accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening ... Talker Award, an essay contest in which patients and their families pay tribute to ... at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016 Bracket , ... launch its next generation clinical outcomes platform, Bracket eCOA (SM) ... held on June 26 – 30, 2016 in ... first electronic Clinical Outcome Assessment product of its kind to ... #715. Bracket eCOA 6.0 is a flexible platform ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 ... Tomorrow,s Leaders Scholarship is any indication, the future is ... online at www.diabetesscholars.org by the Diabetes Scholars ... in the way of academic and community service excellence. ... program since 2012, and continues to advocate for people ...
(Date:6/23/2016)... 2016 Revolutionary technology includes multi-speaker ... , industry leaders in advanced audiology and hearing aid ... Opn ™, the world,s first internet connected hearing aid ... devices.      (Photo: http://photos.prnewswire.com/prnh/20160622/382240 ) ... of ,world firsts,: , TwinLink™ - the ...
Breaking Medicine Technology: