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$1.4 million grant awarded to study 2 little-understood neurological disorders
Date:12/18/2007

isturbances in gait, balance, control of urination and memory.

This investigation will be led by Dr. Norman Relkin, an authority in the diagnosis of the condition and author of international guidelines for the diagnosis of NPH. He is director of the Memory Disorders Program at NewYork-Presbyterian Hospital/Weill Cornell Medical Center and associate professor of clinical neurology and neuroscience at Weill Cornell Medical College.

"NPH is treatable, but grossly under-recognized. Sadly, its symptoms are too often mistaken for Alzheimer's, Vascular Dementia or Parkinson's disease," explains Dr. Relkin. "There is currently no single method for objectively diagnosing NPH, and the available means of diagnosis involve a costly and time-consuming combination of clinical examinations, brain imaging and cerebrospinal fluid (CSF) drainage procedures. Furthermore, in published studies, the accuracy of this conventional approach is only about 50 percent in the hands of most physicians."

The three-year study will examine two techniques: Quantitative Diffusion Tensor Magnetic Resonance Imaging (QDT-MRI) and Proteomic Analysis of Cerebrospinal Fluid (PA-CSF) -- approaches Dr. Relkin says "have shown excellent promise in our preliminary study and could revolutionize NPH diagnosis and management."

Shelby White, founding trustee of the Leon Levy Foundation, says, "Leon was interested in the function of the human brain and its effects on behavior. He also had a very high regard for the work of Dr. Norman Relkin. This important research should advance our knowledge of these two perplexing neurological disorders. We have great confidence in the excellence of Dr. Relkin and Dr. Correa, and the NewYork-Presbyterian/Weill Cornell neurological program, and are therefore pleased to support this critical effort."


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Contact: Andrew Klein
ank2017@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

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