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Protein C


Protein C is a major physiological anticoagulant. It is a vitamin K-dependent serine protease enzyme (EC 3.4.21.69) that is activated by thrombin into activated protein C (APC). The activated form degrades Factor Va and...
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Protein C deficiency is a rare genetic trait that predisposes to thrombotic disease. It was first described in 1981. The disease belongs to a group of genetic disorders known as thrombophilias. The prevalence of protein C deficiency has been estimated to about 0.2% to...
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protein C n. A vitamin-K dependent plasma protein that enzymatically cleaves activated forms of factors V and VIII, thus inhibiting the coagulation of
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Protein C is a substance that prevents ... lack (deficiency) of protein C can lead to ... Protein C deficiency can be either passed down through families ...
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... mutation, deficiencies in protein S, ... and organization of the human protein C gene. Proc Natl Acad Sci U ... cytoprotective protein C pathway. Blood ...
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Protein C deficiency is a genetic trait that predisposes one to the formation of ... The function of protein C is to inactivate factor Va and factor VIIIa (the 'a' ...
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A lack (deficiency) of protein C can lead to excess clotting. ... Protein C deficiency can be either passed down through families (inherited) or ...
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Protein C is a Vitamin K-dependent protease that functions as an anticoagulant ... This was expected given the role of Protein C in inhibiting factors Va and VIIIa. ...
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Activated Protein C is a serine protease which functions to inactivate Factors Va and VIIIa. ... normal level of Protein C, but decreased functional activity. ...
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Mouse protein-coding gene Proc. Represented by 121 ESTs from 30 cDNA libraries. ... Mus musculus protein C, mRNA (cDNA clone MGC:13870 IMAGE:4211329), complete ...
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List of 5 disease causes of Decreased protein C, patient stories, diagnostic guides. Diagnostic checklist, medical tests, doctor questions, and related signs or ...
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Results: The dynamics of the anticoagulant, anti-inflammatory and pro-fibrinolytic action of rhAPC in patients with ... deficient in protein C inhibitor with ...
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Severe protein C deficiency (i.e. protein C activity <1 IU dL1) is a rare ... Low levels of plasma protein C were first associated with venous thrombosis in a ...
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Protein C - Overview, Protein C is a substance that prevents blood clotting. ... Protein C and protein S help regulate blood clotting. ...
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The world's first wiki where authorship really matters. Due credit and ... Activated protein C reduces stress-induced gastric mucosal injury in rats by ...
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Protein C deficiency can be either passed down through ... Clot-related events, like clots in the lung (pulmonary embolism), reduce protein C and S levels. ...
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