McCune

McCune-Albright syndrome: A genetic disorder of bones, skin pigmentation and hormonal problems with premature sexual development. Also called Albright syndrome or polyostotic fibrous dysplasia.
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MCCUNE-ALBRIGHT SYNDROME - The abnormal development of multiple bones, hormonal disorder, and brownish skin lesions.
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McCune-Albright syndrome is a genetic disease affecting the bones and pigmentation of the skin, which also causes hormonal problems and premature sexual development.
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Anterior Skeletal Anatomy ...
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No consistent familial or hereditary factors have been identified. However, a genetic mutation of the Gs alpha gene has been identified in patients with McCune-Albright syndrome.
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Mono -- one bone is affected
Polyostic -- several bones are affected
McCune Albright -- in addition to the bone abnormalities, there are skin pigmentation and endocrine abnormalities.
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El gigantismo tambin puede ser causado por condiciones mdicas subyacentes tales como la neoplasia endocrina mltiple tipo-1 (NEM 1), el sndrome de McCune-Albright (SMA), la neurofibromatosis o el complejo de Carney.
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