Navigation Links
Hematopathology


Hematopathology is the branch of pathology which studies diseases of hematopoietic cells (see below). A hematopathologist looks at peripheral blood smears, bone marrow aspirates and biopsies, lymph nodes, and other tissues, and uses his/her expertise to diagnose diseases such as lymphomas and leukemias. The hematopathologist uses traditional microscopy to look at the specimen, but also relies on laboratory values, immunohistochemistry, flow cytometry, and molecular diagnostic tests to make the most accurate diagnosis. The hematopathologist works closely with the hematologist/oncologist specialty doctor who sees the patient and decides on the best treatment based upon the diagnosis.

Diseases of Hematopoietic Cells

The major disease of hematopoietic cells fall into several categories, which include chronic myeloproliferative disease, myelodysplastic syndromes, leukemias, lymphomas, plasma cell neoplasms, and histiocytic and mast cell neoplasms. Hematopathologists from all over the world have agreed on a standard classification system, called the "WHO classification".[1] Leukemias are mainly bone marrow and blood based and can be subclassified as chronic leukemia and acute leukemia. Chronic leukemia is the proliferation of too many mature blood cells, and is called that because it is a chronic process clinically. Examples are chronic myelogenous leukemia and chronic lymphocytic leukemia. Acute leukemia is the proliferation of too many immature blood cells, called myeloblasts, which have lost the ability to become mature cells. This is usually a very aggressive disease if untreated. Fortunately, treatment of both types of leukemia has improved greatly over the past few decades. Lymphomas are diseases that are mainly based in lymph nodes. Hematopathologists have named different lymphomas after the type of lymphocyte that has become malignant. Thus there are B cell lymphomas, T cell lymphomas, and NK cell lymphomas. The hematopathologist uses immunohistochemistry and flow cytometry, techniques using antibodies to specific lymphocyte surface markers, to determine the type of lymphoma in the pathology specimen.

Notes

  1. ^ Jaffe, ES, Harris, NL, Stein, H., and Vardiman, JW, eds. Pathology and Genetics: Tumours of Haematopoietic and Lymphoid Tissues, World Health Organization Classification of Tumors Series. Lyon: IARC Press, 2001.

External links



'"/>


(Date:3/29/2017)... ... March 29, 2017 , ... The Professional Squash Association, ... enlisted New York City-based sports and entertainment marketing firm Leverage Agency as its ... for the Professional Squash Association (PSA), which includes first-time ever title sponsorship, naming ...
(Date:3/29/2017)... ... ... pollen is the main cause of hay fever in the United States, with an estimated ... from May to July each year; with the worst time for sufferers being June and ... ( http://www.haymax.us ) provide an effective defense against grass pollen; they are proven in independent ...
(Date:3/29/2017)... (PRWEB) , ... March 30, 2017 , ... Youth Futures ... great success and feedback from high school and college students who have participated in ... held July 7-23 and YFI is now accepting applications for enrollment. Visit ...
(Date:3/29/2017)... (PRWEB) , ... March 30, 2017 , ... Sports Brand ... brace, which retails normally at $29.97; for the remaining days of March, the ... also been reduced to a special price of just $10 (regular retail price $19.97). ...
(Date:3/29/2017)... Louisiana (PRWEB) , ... March 29, 2017 , ... ... in three Hours at a Walgreens store in Mississippi. AngioGenesis Labs, makers of ... Walgreens Stores in two southeastern states. Ingredients in HeartBoost, an over the counter ...
Breaking Medicine News(10 mins):
Other medicine definition