Navigation Links
Hematopathology


Hematopathology is the branch of pathology which studies diseases of hematopoietic cells (see below). A hematopathologist looks at peripheral blood smears, bone marrow aspirates and biopsies, lymph nodes, and other tissues, and uses his/her expertise to diagnose diseases such as lymphomas and leukemias. The hematopathologist uses traditional microscopy to look at the specimen, but also relies on laboratory values, immunohistochemistry, flow cytometry, and molecular diagnostic tests to make the most accurate diagnosis. The hematopathologist works closely with the hematologist/oncologist specialty doctor who sees the patient and decides on the best treatment based upon the diagnosis.

Diseases of Hematopoietic Cells

The major disease of hematopoietic cells fall into several categories, which include chronic myeloproliferative disease, myelodysplastic syndromes, leukemias, lymphomas, plasma cell neoplasms, and histiocytic and mast cell neoplasms. Hematopathologists from all over the world have agreed on a standard classification system, called the "WHO classification".[1] Leukemias are mainly bone marrow and blood based and can be subclassified as chronic leukemia and acute leukemia. Chronic leukemia is the proliferation of too many mature blood cells, and is called that because it is a chronic process clinically. Examples are chronic myelogenous leukemia and chronic lymphocytic leukemia. Acute leukemia is the proliferation of too many immature blood cells, called myeloblasts, which have lost the ability to become mature cells. This is usually a very aggressive disease if untreated. Fortunately, treatment of both types of leukemia has improved greatly over the past few decades. Lymphomas are diseases that are mainly based in lymph nodes. Hematopathologists have named different lymphomas after the type of lymphocyte that has become malignant. Thus there are B cell lymphomas, T cell lymphomas, and NK cell lymphomas. The hematopathologist uses immunohistochemistry and flow cytometry, techniques using antibodies to specific lymphocyte surface markers, to determine the type of lymphoma in the pathology specimen.

Notes

  1. ^ Jaffe, ES, Harris, NL, Stein, H., and Vardiman, JW, eds. Pathology and Genetics: Tumours of Haematopoietic and Lymphoid Tissues, World Health Organization Classification of Tumors Series. Lyon: IARC Press, 2001.

External links



'"/>


(Date:3/20/2019)... JERSEY CITY, N.J. (PRWEB) , ... March 20, 2019 , ... ... 2019 Texas Regional Healthcare Information Management Systems Society (HIMSS) conference in Austin, Texas on ... by GRM’s booth (#523) to learn more about GRM’s healthcare information management solutions ...
(Date:3/20/2019)... ... March 20, 2019 , ... Vera Whole Health , ... paper that examines how on-site clinics keep employees healthy and drive down the total ... employers understand the benefits of adopting on-site clinics. , The Vera white paper ...
(Date:3/20/2019)... ... March 20, 2019 , ... Natreon has ... composition of trivalent chromium chloride combined with extracts of amla and shilajit, that ... granted patent, along with 7 clinical studies on Crominex®3+, establish this ingredient as ...
(Date:3/20/2019)... (PRWEB) , ... March 20, 2019 , ... ... a new CBD oil vape brand – Mingo Rad. , Mingo Rad ... exclusively from domestic hemp and crafted with a unique manufacturing process, Mingo Rad ...
(Date:3/20/2019)... ... ... Caring.com, the nation’s most visited website for senior living reviews, has named ... provider was recognized as the Best Standalone Mobile App . , LifeFone ... demonstration of excellent customer service, transparency and affordability. With a variety of medical alert ...
Breaking Medicine News(10 mins):
Other medicine definition