Navigation Links
YOUR DATA: ,,, Direct Real-time RT-PCR on Sympathetic Neuron Lysates,,, ,,, Silencing of Focal Adhesion Kinases with Silencer Validated siRNAs

back to top]

Ambion, in partnership with Cenix BioScience, has manufactured and validated siRNAs targeting a number of important human genes. These Silencer Validated siRNAs are individual siRNA duplexes that have been verified experimentally to reduce the mRNA levels of their target genes by at least 70%. The use of validated siRNAs saves researchers both time and money that can be better spent answering specific biological questions. Here is one example of how validated siRNAs were used in gene silencing studies.


Silencing of Focal Adhesion Kinases
Malignant gliomas such as glioblastomas are a leading cause of CNS tumor-related death. At the root of the problem is the highly invasive behavior of glioblastomas. Glioblastoma migration, like that of other cell types, is a dynamic process ultimately dependent upon the interplay between the integrin family of cell adhesion receptors and extracellular matrix environments. Integrin receptors are known to affect the dynamic balance of various non-receptor tyrosine kinases that function as effectors of integrin mediated signaling. Dr. Joseph Loftus of the Mayo Clinic, Scottsdale has been examining the role of two potential proximal integrin effectors--the closely related focal adhesion kinases FAK (PTK2) and Pyk2 (PTK2B) -- in the temporal development of the proliferative or migrational
'"/>

Source:


Page: All 1 2 3 4 5

Related biology technology :

1. YOUR DATA: Direct Real-time RT-PCR on Sympathetic Neuron Lysates Silencing of Focal Adhesion Kinases with Silencer Validated siRNAs
2. Measuring RNase Activity A Real-time Kinetic Analysis
3. Ready for Real-time in 5 Minutes
4. New Kit Generates Exceptionally Pure Total RNA for RT-PCR
5. Brilliant Core Reagent Kits for QPCR and QRT-PCR
6. Control RT-PCR Primers for Human Gene Transcripts with Varying Abundance
7. prostar RT-PCR Systems for Robust High-Fidelity RNA Amplification
8. Performance Comparisons of Commercial RT-PCR Systems
9. RT-PCR Primer Sets for Human and Mouse Mismatch Repair Genes
10. RT-PCR Primers for the Study of Apoptosis
11. cMaster RTplusPCR System for increased sensitivity and product length in RT-PCR
Post Your Comments:
(Date:7/11/2014)... Research and Markets  has announced the ... Global Industry Analysis, Size, Share, Growth, Trends and Forecast ... http://photos.prnewswire.com/prnh/20130307/600769 Transfection is ... or RNA) into cells. This technology helps the cells ... protein metabolism by affecting the nuclear genes. The transfection ...
(Date:7/11/2014)... July 11, 2014 Cayenne Medical, ... specializing in the soft tissue reconstruction segment, announced ... System for surgeries involving the shoulder and extremities. ... a novel, inserter-controlled deployment method. The unique delivery ... deployment, anchor pull-out, or anchor displacement (also commonly ...
(Date:7/10/2014)... Terascala, the industry leader in ... a former vice president of product management for Flexera ... of marketing. Terascala’s software when combined with leading compute ... highest performance and most reliable solutions for processing big ... channel expansion and broaden its product portfolio. His leadership ...
(Date:7/10/2014)... July 10, 2014 Senior supply chain ... professional associations, addressed the challenges of “Reducing Cost, Lead ... Industries” through strategic sourcing. Describing the partnership of the ... Supply Chain Management Institute ( SCMI) of the ... June 24 at the Kroc Institute of Peace and ...
Breaking Biology Technology:International Transfection Technology Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2019 2Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 2Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 3Terascala Expands Executive Team 2Terascala Expands Executive Team 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 2Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 4
... experts are urging that food additives that contain nanoscale ... that their use does not pose unintended risks. , ... regulatory challenge facing the incoming Obama administration. It also ... Food and Drug Administration (FDA) and possibly create a ...
... Once thought of as,a technology used only for ... CUDA(TM) technology are now being used for the,serious ... Network Computing (BOINC), one of the leading distributed ... to tap the massively parallel,processing power of NVIDIA ...
... DIEGO, CA, Dec. 17, 2008 Senomyx, Inc.,(Nasdaq: ... on using proprietary taste receptor,technologies to discover and ... ingredient supply industries, announced today that Kent Snyder,the ... Vice President,Chief Financial and Business Officer, will present ...
Cached Biology Technology:Experts argue nano food-additives require new oversight 2NVIDIA CUDA Technology Dramatically Advances the Pace of Scientific Research 2NVIDIA CUDA Technology Dramatically Advances the Pace of Scientific Research 3NVIDIA CUDA Technology Dramatically Advances the Pace of Scientific Research 4NVIDIA CUDA Technology Dramatically Advances the Pace of Scientific Research 5NVIDIA CUDA Technology Dramatically Advances the Pace of Scientific Research 6SENOMYX TO WEBCAST CORPORATE PRESENTATION AT THE 11TH ANNUAL NEEDHAM GROWTH STOCK CONFERENCE 2
(Date:7/11/2014)... fire started near the City of Entiat on Tuesday, ... the fire quickly grew to over 1,000 acres by ... fire is under investigation by the Washington Department of ... existing local resources in developing fire control strategies and ... Washington State Department of Natural Resources, (WA DNR), Bureau ...
(Date:7/11/2014)... in German . ... uses the refraction of X-rays through a specimen instead ... this method are often of much higher quality than ... of Prof. Franz Pfeiffer are particularly interested in developing ... including X-ray phase-contrast imaging. One main goal is to ...
(Date:7/11/2014)... 10, 2014---A team of researchers from The Chinese University ... a gene of wild soybean linked to salt tolerance, ... in saline soil. This study published online in ... novel genomic information for crop improvement. , Soybean is ... and human selection, cultivated soybeans have less genetic diversities ...
Breaking Biology News(10 mins):New simple setup for X-ray phase contrast 2BGI reports a novel gene for salt tolerance found in wild soybean 2
... locations that raise the risk of type 1 diabetes. ... genetic puzzle for this disease, the researchers expect to ... we add to our knowledge of the biology of ... disease,s genetic risk, we will be able to develop ...
... Lange will receive a $900,000 check from Donald ... (EPA) Region III which includes Pennsylvania, Virginia, ... Columbia for continued research and education in ... dormant and underused industrial or commercial properties. The ...
... from extreme environments to overcome the challenges of producing ... UK,s John Innes Centre, the Scripps Research Institute in ... a stable, modifiable virus that could be used as ... sized, can be produced in large quantities, and are ...
Cached Biology News:Researchers continue to find genes for type 1 diabetes 2Extreme nature helps scientists design nano materials 2
... critical to the maintenance of appropriate ... as important and diverse as those ... and stress response, antigen presentation, modulation ... channels, cell cycle regulation, transcription, and ...
... Proteolytic degradation is critical to the ... and regulatory proteins as important and ... metabolism, heat shock and stress response, ... receptors and ion channels, cell cycle ...
... The LIBS-ELITE houses Ocean Optics LIBS2000+ ... Research Universal Platform (UP) Ablation Chamber to ... position control. The systems features include a ... and targeting functions, precise X-Y sample positioning, ...
... modified digital scanner serves as the spot-picking ... five standard rack positions on the tray, ... well plates on the remaining two racks.,The ... spots by mouse-click on the scanned gel ...
Biology Products: