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What patients want: A story of choice, clinical trials & evidence-based medicine

Clinical trials are serious business. In addition to being big business (untold billions of dollars every year), they also involve serious ethical issues and choices. We are all aware of the fundamental ethical principle of informed consent underlying all clinical trials.

What is less obvious is that co......

Full article >>> A Randomized Trial summarized this important clinical trial. They were also accompanied by two editorials and the trial results were significant enough to raise the attention of the national media, including an article in the New York Times - Study Ques......

Full article >>> the extremely high numbers of crossovers (45 to 60 percent of patients) and, to a lesser extent, a certain degree of missing data, such analyses are significantly confounded and should not be used to compare different strategies, as Dr. David Flum, a contributing editor at JAMA, wrote in his accompanying editorial.

Instea......

Full article >>> e? Where their pain thresholds higher yet their risk tolerance less? While the study yielded indefinite results, this much is for sure: patients want (and certainly act upon) choice.

It was a bit disappointing then to read further in the JAMA editorials that designing clinical trials with sham-controlled surgeries (e.g. operations in which the patient is cut but the actual restorative pr......

Full article >>> s="AuthorBio">Dr. Ogan Gurel is chairman of the Aesis Research Group, which provides forward-looking information and research services to the healthcare and life sciences investment community. Gurel was previously CEO of Duravest, a publicly traded Chicago investment company that initiates and develops next-generation medical technologies. Previous to Duravest, he was a vice president and medical ......

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Source:wistechnology.com By Ogan Gurel 03/19/07


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