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UW-Madison scientists find a key to cell division

MADISON - A cellular structure discovered 125 years ago and dismissed by many biologists as "cellular garbage" has been found to play a key role in the process of cytokinesis, or cell division, one of the most ancient and important of all biological phenomena.

The discovery of the function of the dozens of proteins harbored within this structure - which are necessary for normal cell divis......

Full article >>> aide in wound healing, for example.

During the cell cycle, the genetic information the cell contains is copied and segregated into two new cells. During normal division, the outer membrane of the cell pinches in, forming two separate cells. Although a very simple event, scientists had not fully understood the mechanisms or identified the proteins involved in separating the two newly forme......

Full article >>> approach. The fact that the process is highly conserved across two very different species shows how ancient and conserved the process of cell division is."

The team analyzed 160 key proteins - including 103 not previously known to function in cell division - and found that 58 percent caused cytokinesis defects if they were inactivated.

"The problems ranged from cells where chrom......

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'"/> By Katie Weber 05/31/04

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