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TissueRuptor System

For low-throughput disruption of a wide range of biological samples using disposable probes


The TissueRuptor system enables rapid, efficient, and flexible disruption of a variety of biological samples, including animal and human tissues and cells and plant tissue.

The TissueRuptor system provides:
  • Disposable probes to help eliminate cross-contamination by using a new probe for each sample
  • Rapid and efficient disruption reliable disruption of a wide range of sample types
  • Time savings disposable probes are simply discarded after disruption of each sample
  • Optimized protocols seamless integration with proven QIAGEN technologies for purification of RNA, DNA, or protein
  • Flexibility compatible with different sample types, lysis buffers, and disruption vessels


  • Rapid and efficient sample disruption with disposable probes to help prevent cross-contamination
    The TissueRuptor is a handheld rotorstator homogenizer that provides rapid and efficient disruption of individual samples for a wide range of downstream applications. Disruption at full speed for as little as 30 seconds using a disposable probe is usually sufficient to release nucleic acids or proteins from starting material.

    TissueRuptor Disposable Probes enable convenient and flexible sample disruption in a wide range of volumes and formats. Using a disposable probe for each sample helps to eliminate cross-contamination, which is especially important for highly sensitive downstream applications, such as real-time PCR or
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