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The birth of biotech: San Francisco, Boston, Geneva or Chicago?

CHICAGO To start off our day, heres a pop biotech quiz to see if you know your biotech history and trivia:
  1. What were the first six biotech companies?
  2. How many of these companies still exist?
  3. How many of them are still completely independent?

While Im willing to bet that most of you will get at least three of the six companies right in the first question, ......

Full article >>> "">Wyeth.

Cetus, originally located in San Francisco and founded in the late 1970s as an innovative cancer therapy company, was acquired by Chiron in the early 1990s.

Amgen, which was originally known as Applied Molecular Genetics, was founded......

Full article >>> st monoclonal antibodies are produced.
  • 1977: The first expression of a human gene in bacteria.
  • 1978: Recombinant insulin is first produced.
  • 1979: Human growth hormone is first synthesized.
  • Also in the 1970s: RNA splicing, gene targeting, discovery of polymerases and of course the first commercial companies to develop genetically engineered products.
    During ......

    Full article >>> sity of Chicago.

    Goldwasser was born in 1922 (hes 82 today) in Brooklyn. After his family moved to Kansas City, he won a scholarship to University of Chicago and majored in biological sciences. During his initial time there, Goldwasser worked in the universitys toxicity lab on antidotes for chemical warfare agents (this was after the Japanese attack on Pearl Harbor).

    Upon graduat......

    Full article >>> o three dialysis patients with his small supply of EPO.

    His goal was to demonstrate an effect on patients with anemia of chronic renal disease. He also advised the University of Chicago and the government that he had a patentable invention. When he didnt hear back from these groups, he forgot about patenting his discovery.

    The results of his small Phase I were promising but incon......

    Full article >>> years later for $250 million). This helped the new company attract west coast VCs, which put up another $12 million. With this investment, the new company was off and running.

    Once funded, EPO became one of the lead projects and Salser invited Goldwasser to join the new Amgens scientific advisory board. Goldwasser preferred to work for Amgen as a consultant and Goldwasser provided Amgen ......

    Full article >>> wasser continued to investigate other aspects of EPO and focused on the kidney cells that produce EPO. While Amgen continued to support his lab at the rate of about $30,000 per year, the NIH lost interest in his work.

    As Goldwasser never patented any of his work, his financial share of Amgens successful sales of EPO never materialized.

    Still, he clearly was the pivotal person in ......

    Full article >>>

  • By Michael Rosen 08/25/04

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