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The New Affymetrix GeneChip Scanner 3000

on. The data for all SLR comparisons showed equivalence in the GeneChip Scanner 3000 and GeneArray 2500 performance.

The comparisons in Figure 6 are the most challenging because the target spike concentrations of 0.75 pM and 1.50 pM are close to the limit of detection of the assay. The average SLR ranges for 0.75 pM versus 1.50 pM were 0.61-0.70 and 0.57-0.69 for the GeneChip Scanner 3000 and GeneArray 2500, respectively. The average SLR ranges for 1.50 pM versus 3.00 pM were 0.79-0.85 and 0.81-0.84 for the GeneChip Scanner 3000 and GeneArray 2500, respectively. These values of

Conclusion

The results for human genome probe arrays described in this Technical Note clearly indicate that the performance of the GeneChip Scanner 3000 is equivalent to or better than the performance of the GeneArray 2500. Where statistical analysis was applied, Students t-tests provided substantial evidence of performance equivalence of the two scanner types. In the subset of cases where a bias may have been indicated, most favored the performance of the GeneChip Scanner 3000.

At Affymetrix, we take pride in the high quality of products we develop and support. We are pleased to Conclusion AFFYMETRIX UK Ltd Voyager, Mercury Park, Wycombe Lane, Wooburn Green, High Wycombe HP10 0HH United Kingdom Tel: +44 (0)1628 552550 Fax: +44 (0)1628 552585 saleseurope@affymetrix.com supporteurope@affymetrix.com www.affymetrix.com AFFYMETRIX, INC. 3380 Central Expressway Santa Clara, CA 95051 USA Tel: 1-888-362-2447 (1-888-DNA-CHIP) Fax: 1-408-731-5441 sales@affymetrix.com support@affymetrix.com For research use only. Not for use in diagnostic procedures. Part No. 701218 Rev. 1 2003 Affymetrix, Inc. All rights reserved. Affymetrix,GeneChip, , , , HuSNP, Jaguar, EASI, MicroDB, GenFlex
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1. Fine Tuning Your Data Analysis: Tunable Parameters of the Affymetrix Expression Analysis Statistical Algorithms
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3. GeneChip Sample Cleanup Module for cleanup of cDNA and in vitro transcribed cRNA
4. New statistical algorithms for Monitoring Gene Expression on GeneChip® Probe Arrays
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