Navigation Links
The Flexible matriXarray Chip System: A New Perspective,,,for Probe Optimization in Gene-Expression Profiling

und correction and normalization between the tissues via housekeeping genes was calculated. To demonstrate the approach, the resulting probe profiles of one gene for each tissue are displayed in Figure 3.

The comparison of probe profiles reveals the similar behavior of some probes, while others show distinct differences. For the brain-specific gene (GenBank acc. no. AB049056), all five probes show the same tendency; however, probes 3 and 4 display the most preferred pattern due to their high degree of profile similarity and specificity for the brain tissue. Representing the liver-specific gene (GenBank acc. no. J02585), probes 2, 5, and 6 display similar attributes; however, especially probes 4 and 7 show a more distinct pattern (a high signal in brain and/or kidney and a lower signal in liver compared to the other probes), indicating a dysfunction of these two probes. For the kidney- specific gene (GenBank acc. no. AF062389), probes 2, 5, 6, and 7 seem to be specific, while probes 1, 3, and 4 show aberrations in their intensity pattern.

In an ongoing study, the expression levels of 130 genes in 5 different human tissues are analyzed. The goal of this study is to establish an automated workflow for probe selection.

Fast and Convenient Iteration of Chip Layout

In conclusion, the data shown here demonstrate the impact of experimental probe validation in gene-expression profiling experiments. Based on the high flexibility in the production of customized chips, the matriXarray Chip System is the first platform that allows a fast and convenient iteration of chip layouts. Since probe optimization is crucial for all microarray applications, future work will extend this approach to applications outside of ex
'"/>

Source:


Page: All 1 2 3 4

Related biology technology :

1. The LightCycler is the only System for Quantitative PCR that is as Flexible as You are!
2. TripleMaster PCR System: Direct Comparison with Competitors
3. New Microarray Labeling Kit for Preparing cDNA Probes
4. QuantiTect Probe PCR Kit
5. RNase Protection Assay (RPA) Using DIG-Labeled RNA Probes
6. Detection of mRNAs on Cryosections of the Cardiovascular System Using DIG-Labeled RNA Probes
7. Prepare siRNA and miRNA Probes in Just 1 Hour
8. Rapidly Prepare Probes and Markers for Small RNA Analysis
9. New statistical algorithms for Monitoring Gene Expression on GeneChip® Probe Arrays
10. Two-dimensional Optimization of a Semi-nested PCR for Detecting Listeria monocytogenes
11. PCR Optimization
Post Your Comments:
(Date:9/1/2015)... YORK , Sept. 1, 2015 /PRNewswire-USNewswire/ ... of cancer death in American men. One ... cancer and 233,000 new cases are diagnosed annually. ... experts are using a powerful new technique, ... small and large cancer lesions, treating only the ...
(Date:9/1/2015)... ... September 01, 2015 , ... In her thought provoking debut novel ‘ ... a not-so-distant future faced with an Ebola pandemic that is on the cusp of ... to enter the world of counterterrorism, and who continues to appear in this series ...
(Date:9/1/2015)... ... September 01, 2015 , ... ... , Equine cervical facet joint problems can be caused by injuries and ... cause impingement of nerve roots or of the spinal cord itself. This can ...
(Date:9/1/2015)... ... 01, 2015 , ... Leading CEOs, CSOs, CMOs, and heads ... join prominent academics and key investors for Neuro Advance Boston, October 14, 2015 ... , Neuro Advance Boston focuses on the latest developments and opportunities in ...
Breaking Biology Technology:September Is Prostate Cancer Awareness Month 2September Is Prostate Cancer Awareness Month 3September Is Prostate Cancer Awareness Month 4Alexi Venice’s Debut Novel Takes on the Human Testing of a Vaccine for Ebola and Revenge by an Anti-Big Pharma Terrorist Group in ‘Ebola Vaccine Wars' 2Alexi Venice’s Debut Novel Takes on the Human Testing of a Vaccine for Ebola and Revenge by an Anti-Big Pharma Terrorist Group in ‘Ebola Vaccine Wars' 3VetStem Biopharma Announces New Clinical Research Program for Equine Cervical Facet Joint Disease 2VetStem Biopharma Announces New Clinical Research Program for Equine Cervical Facet Joint Disease 3Neuro Advance Boston Brings Together Leading Neuroscience Experts on October 14 at Harvard Medical School 2
... PRAIRIE, Minn., Oct. 7 ACIST Medical Systems,Inc., ... 75,000 square foot,expanded corporate Headquarters and manufacturing facility ... and Eden Prairie Mayor Phil Young will,join Fulvio ... a ribbon cutting,ceremony at the company,s new facilities. ...
... Calif., Oct. 7 Nektar,Therapeutics (Nasdaq: NKTR ) ... at the upcoming Natixis Bleichroeder Second Annual Hidden Gems,Conference ... October 13,2008 at 2:30 p.m. ET., The presentation ... the Investor Relations, Events Calendar section of the Nektar ...
... is a prominent expert on RNAi, delivery ... Paris, France, is foremost authority on bacterial ... Pharmaceuticals, a,pioneer in the development of novel products to ... that two of the,leading scientists in RNA Interference (RNAi) ...
Cached Biology Technology:ACIST Medical Systems Announces the Opening of Its New Expanded Corporate Headquarters in Eden Prairie, MN 2ACIST Medical Systems Announces the Opening of Its New Expanded Corporate Headquarters in Eden Prairie, MN 3Two Luminaries Join Cequent Scientific Advisory Board: Judy Lieberman, M.D. Ph.D., and Patrice Courvalin, M.D. 2Two Luminaries Join Cequent Scientific Advisory Board: Judy Lieberman, M.D. Ph.D., and Patrice Courvalin, M.D. 3
(Date:9/2/2015)... 2, 2015 Biometric ... in a system which uses identical human characteristic ... vein, DNA and finger print. Increasing number of ... such system which provides high level of security. ... and tokens are vulnerable to attacks. Furthermore, Biometric ...
(Date:8/28/2015)... , August 28, 2015 ... and Training Market by Assessment Type (Pen & Paper ... Brain Training, Corporate Learning, Academic Research), Vertical and Region ... Assessment and Training Market to grow from USD 2.4 ... at a Compound Annual Growth Rate (CAGR) of 25.6% ...
(Date:8/24/2015)... MOUNTAIN VIEW, Calif. , Aug. 24, 2015  Based ... & Sullivan recognizes DERMALOG with the 2015 African Biometrics Company ... manufacturer and has achieved substantial commercial success in ... Nigeria , where it has implemented one of ... equipped 23 banks as well as the Central Bank of ...
Breaking Biology News(10 mins):Biometrics Technology Market is Expected to Reach $13.8 Billion by 2015: Hexa Research Inc. 2Biometrics Technology Market is Expected to Reach $13.8 Billion by 2015: Hexa Research Inc. 3Biometrics Technology Market is Expected to Reach $13.8 Billion by 2015: Hexa Research Inc. 4Cognitive Assessment and Training Market Worth 7.5 Billion USD by 2020 2Cognitive Assessment and Training Market Worth 7.5 Billion USD by 2020 3Cognitive Assessment and Training Market Worth 7.5 Billion USD by 2020 4Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 2Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 3Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 4Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 5Frost & Sullivan Applauds DERMALOG's Rise as the Supplier of Best-in-class Biometric Solutions in Africa 6
... food prices driven down by unprecedented advances in agricultural ... wheat have tripled and those for maize and rice nearly ... will fall soon. On the contrary, economists expect larger and ... and its devastating impacts on agriculture adding greatly to the ...
... ScD, Associate Professor of Surgery at the University of ... Hospital, has been awarded a $3 million grant from ... work in molecular cardiac surgery: a unique approach to ... four-year grant will enable Dr. Bridges to expand upon ...
... security market in EMEA spurs IdentiPHI,s company ... ... in enterprise security solutions and services, announces its,expansion with the opening of ... for identity and authentication (access,management) products and solutions., "Opening the office ...
Cached Biology News:Agriculture experts meet in Beijing to examine impacts of food prices and climate change on farmers 2Pennsylvania Hospital surgeon receives grant to develop molecular cardiac surgery 2Pennsylvania Hospital surgeon receives grant to develop molecular cardiac surgery 3IdentiPHI Opens Paris Office to Boost European Sales and Support 2
...
Sheep polyclonal to Quinolone ( Abpromise for all tested applications). Antigen: Norfloxacin(N)conjugated to BSA...
Certified U.S. origin. Bovine Serum:, *Certified U.S. origin. Available raw, nonsterile filtered, or sterile filtered. , , *Sterility tested , , *Low Hemoglobin levels , , *Mycoplasma testing upon...
...
Biology Products: