Navigation Links
The Affymetrix GeneChip Scanner 3000,,, New Advances in Scanner Design for Superior Performance, Reliability, and Dynamic Range

a acquisition electronics have been implemented using the latest generation of high-speed sampling analog-to-digital converters. The use of high-quality electronic components is critical; however, it is only part of the story. The best components in the world cannot differentiate between real signal from fluorescent emissions, and noise signal caused by radiated or conducted pick-up resulting from poor circuit implementation. Electrical pollution of signals can be caused by proximity to nearby conductors carrying dirty signals, local radio or television stations, or certain types of equipment plugged into the same power source. Sampled data are used to create a snapshot in time of the signal that is presented to the system regardless of its origin. Considerable design effort was put into the optimization of the data acquisition electronics packaging and printed circuit layout to ensure exceptional immunity from external noise sources. Affymetrix specifically custom- designed and continues to build this key sub-system in the manufacturing facility to ensure complete control of the design and manufacturing quality.

REDUCED MEASUREMENT NOISE

One of the biggest hurdles to getting accurate, high-quality, biological data is measurement noise. There are two main sources of system noiseInstrument and Process. Instrument-related sources include data acquisition electronics (previously discussed), laser output noise, optical nonuniformity, auto-fluorescence of optical components, etc. Process-related sources (that, in general, are not mitigated by scanner design elements) include sample contamination, non-specific binding of fluorophores to array features, and non-uniform hybridization. System noise, or total noise from all sources, causes signal measurement uncertainty, i.e., any given data sample may be inaccurate within the system noise band. Noise becomes a significant issue when measuring very small signals. Generally, when comparing instrum
'"/>

Source:


Page: All 1 2 3 4 5 6 7 8 9 10

Related biology technology :

1. Fine Tuning Your Data Analysis: Tunable Parameters of the Affymetrix Expression Analysis Statistical Algorithms
2. The New Affymetrix GeneChip Scanner 3000
3. GeneChip Sample Cleanup Module for cleanup of cDNA and in vitro transcribed cRNA
4. New statistical algorithms for Monitoring Gene Expression on GeneChip® Probe Arrays
5. General Notes on Primer Design in PCR*
6. siRNA Design Guidelines
7. Avoid siRNA Design Altogether!
8. Cenix-Designed siRNAs for 95% of Human and Mouse Genomes
9. Designing a Successful qRT-PCR Experiment
10. Designing a Better siRNA
11. Designing Controls for siRNA Experiments
Post Your Comments:
(Date:8/22/2014)... Greenville, SC (PRWEB) August 22, 2014 ... that indisputable acknowledgement is a national disgrace. Furthermore, ... part in establishing the current, deplorable state of ... outlined "5 great mistakes," to merely serve as ... convey the extent of colossal failure(s) that have ...
(Date:8/21/2014)... team including DESY scientists has observed tiny quantum vortices ... in the journal Science that the exotic ... nanodroplets. It is the first time that the quantum ... of what is known as superfluid helium, have been ... expectations," says Andrey Vilesov of the University of Southern ...
(Date:8/21/2014)... , Aug. 21, 2014 Telomere Biosciences, ... their Nutraceutical "TELO-20 for Dogs" with Telomerase ... supplement in the world for dogs. Telomeres are ... chromosome in the body. A wealth of ground-breaking ... in Telomere Science and Aging, including Nobel laureates, ...
(Date:8/21/2014)... 2014 OTC Markets Group Inc. ... biotechnology company, on its approval to list on ... OTCQX®, the best marketplace for established U.S. and ... Logo - http://photos.prnewswire.com/prnh/20110118/MM31963LOGO ... of its growth strategy and achievement of this ...
Breaking Biology Technology:5 Great Mistakes in Healthcare and How to Fix Them by Dr. Ira Williams 2Scientists observe quantum vortices in cold helium droplets 2Telomere Biosciences Announces: TELO-20 for Dogs, the World's First Telomere-Lengthening Supplement for Dogs, to Promote Healthy Aging and Longevity 2Telomere Biosciences Announces: TELO-20 for Dogs, the World's First Telomere-Lengthening Supplement for Dogs, to Promote Healthy Aging and Longevity 3OTC Markets Group Congratulates Immune Pharmaceuticals on NASDAQ Listing 2
... BioSciences, Inc. (OTC Bulletin Board: GNLK ... that it ranked number 33 on Technology Fast 500 ... growing technology, media, telecommunications, life sciences and clean technology ... the period 2006-2010. GeneLink,s chief executive ...
... Inc ., a late-stage epigenetics oncology company, announced today that members ... BIO Investor Forum , San Francisco, CA, October ... Target , Panel Discussion: HDACi and Their Progress in the Clinic, ... Healthcare Conference , New York, NY, November 16, 1:30 PM ET ...
... 24, 2011 Modern Plastics, one of the largest ... plastics, has become ISO 13485-2003 certified for the distribution ... Resin. "This is an extraordinary achievement ... service and quality," said Bing J. Carbone, President at ...
Cached Biology Technology:GeneLink BioSciences, Inc. Ranked Number 33 Fastest Growing Company in North America on Deloitte's 2011 Technology Fast 500™ 2GeneLink BioSciences, Inc. Ranked Number 33 Fastest Growing Company in North America on Deloitte's 2011 Technology Fast 500™ 3Syndax Pharmaceuticals to Present at Upcoming Fall Conferences 2
(Date:8/21/2014)... of researchers at Louisiana Tech University has ... consumer-grade 3D printers and materials to fabricate ... and chemotherapeutic compounds for targeted drug delivery. ... and research faculty from Louisiana Tech,s biomedical ... create filament extruders that can make medical-quality ...
(Date:8/21/2014)... resulting in severe abdominal pain, vomiting and systemic inflammation. ... diagnosed with the disease resulting in 1000 deaths. There ... intravenous fluid and nutritional support. , Dr Jason ... the research, said "The major causes of pancreatitis include ... intake combined with a high fat diet. In fact, ...
(Date:8/20/2014)... Researchers at Huntsman Cancer Institute (HCI) at the University ... the gene that encodes BCR-ABL, the unregulated enzyme driving ... the American Cancer Society, nearly 6,000 new cases of ... in use, called tyrosine kinase inhibitors (TKIs), target BCR-ABL ... not cure CML but control it in a way ...
Breaking Biology News(10 mins):Louisiana Tech University researchers use 3D printers to create custom medical implants 2Louisiana Tech University researchers use 3D printers to create custom medical implants 3Insulin offers new hope for the treatment of acute pancreatitis 2Blueprint for next generation of chronic myeloid leukemia treatment 2
... the Smithsonian Institution and the Hawaii Institute of Marine ... created the first frozen bank for Hawaiian corals in ... preserve their diversity in Hawaii. Mary Hagedorn, an adjunct ... the Smithsonian Conservation Biology Institute, leads the laboratory at ...
... underlay many cancers. Rui Martinho at the Instituto Gulbenkian ... in Ghent (Belgium) and Bergen (Norway) will use the ... identified in the test-tube, impact on the way cells ... the Association for International Cancer Research (AICR), will provide ...
... of an old antibiotic may help diabetics avoid a stroke ... researchers report. Minocycline, a drug already under study at ... blood vessels in the brain that increases their stroke risk ... Dr. Adviye Ergul, physiologist in the MCG Schools of Medicine ...
Cached Biology News:Smithsonian scientists help create first frozen repository for Hawaiian coral 2Understanding cancer using the fruit fly 2Antibiotic may reduce stroke risk and injury in diabetics 2
... Desselberger (1995) • This book is ... classical and molecular techniques currently used ... and analysis of virus-specific antibodies and ... presented covering immunoassays, blotting and hybridization ...
Bovine Serum...
Mus musculus junctophilin 2 (Jph2) Antigen: Recombinant Protein...
2.0 GHz Compaq Computer with 512 MB RAM, 32 MB AGP Graphics Card, 40 GB Hard Drive, 1 Serial Port & Open PCI Slot, Windows 2000 OS, MS Office, CD Read/Writer and 18 Flat Panel Monitor...
Biology Products: