Navigation Links
Testing Compressed Air Lines for Microbiological Contamination

An air impaction microbial assessment of your air supply may indicate you have unwanted inhabitants in your compressed air system
RUDY PINA

INTRODUCTION

Manufacturers of medical devices who label their product as sterile may use compressed air in various applications. Applications include injection molding, operation of conveyor belts, and/or aseptic cleaning processes. The manufacturer may use these systems on a continuous basis or on an as-needed basis. The manufacturer may not realize that the compressed air system could be harboring microorganisms.

When the air supply system is operating, it may unleash contaminants which could adversely affect the product, including operational characteristics, by compromising sterile claims, or product aesthetics.

The condition or the quality of the supplied air, from a microbiological standpoint, may not be obvious unless microbiological testing is performed. A simple air impaction microbial assay of compressed air lines, however, will alert the manufacturer to the various types of viable microorganisms that might be present.

Manufacturers of medical devices, pharmaceutical operations, or those classified as sterile fill, are constantly assessing the environmental impact on the product during the manufacturing process. This assessment usually includes the facility, the equipment, and the personnel involved in the assembly process. Sampling may include, but is not limited to, surface sampling, particulate counts, water analysis, and product testing. However, compressed air can easily be overlooked if not initially inserted into the environmental monitoring protocol or identified by an experienced environmental scientist.

The engineering department may design the facility whereby the air compressor is segregated from the area where the product is assembled for logical hygienic
'"/>

Source:


Page: All 1 2 3 4 5 6

Related biology technology :

1. Reliable Assessment of Micronuclei for Genotoxicity Testing in Mice or Rats
2. Restriction Endonucleases Undergo Rigorous QC Testing to Ensure Optimal Performance
3. Bio-Plex Cytokine Immunoassays and ELISA: Comparison of Two Methodologies in Testing Samples From Asthmatic and Healthy Children, Rev A
4. Sciclone ALH Bulk Dispense Precision Testing
5. 96 Well Pipetting Precision Testing Using the Sciclone ALH with a 384 Fixed-Cannula Array
6. Sciclone ALH 3000 Liquid Handler: Functional Characterization of the High Volume Head - Part 1: Plate-to-Plate Precision Testing
7. Precision Testing for the Sciclone Advanced Liquid Handler Z8 Option
8. 384 Well Pipetting Precision and Accuracy Testing Using the Sciclone Advanced Liquid Handler
9. Testing Compressed Air Lines for Microbiological Contamination
10. Stable HeLa Luciferase Reporter Cell Lines Expressing GAL4 Fusion Transactivators
11. A Comparison Study of Lipid Tranfection Reagents in A549, NIH 3T3 and COS-7 Cell Lines
Post Your Comments:
(Date:7/29/2014)... Tough, ultralight foam of atom-thick sheets can be made ... invented at Rice University. , In microscopic images, ... with floors and walls that reinforce each other. The ... and walls of graphene oxide that self-assemble with the ... researchers say the foam could find use in structural ...
(Date:7/29/2014)... generation biofuels are a viable solution to the dilemma of ... is very cheap, this is affecting the biofuels market in ... could be in comparison to natural gas. This, in ... for renewable energy developers to get the economics to work ... certain companies have shifted their focused within renewable energy. ...
(Date:7/29/2014)... 2014 A new report by ... applications and geography) - Size, Share, Global Trends, Company ... Forecast, 2013 - 2020", suggests that the global surgical ... 2020 registering a CAGR of 11.1% from 2014 to ... the electro surgical devices in operative procedures by providing ...
(Date:7/29/2014)... 29, 2014 July 29, 2014 ... in the biotechnology industry, announced that it has ... Inc. to explore financing opportunities that build shareholder ... breakthrough vaccine platform with the potential to transform ... exclusively licensed the well-established LAMP platform from Johns ...
Breaking Biology Technology:Tough foam from tiny sheets 2Renewable Waste Intelligence: Could Renewable Chemicals Be the Future for the Renewable Energy Industry? 2Global Surgical Equipment Market is expected to reach $12.1 billion by 2020 - Allied Market Research 2Global Surgical Equipment Market is expected to reach $12.1 billion by 2020 - Allied Market Research 3Immunomic Therapeutics Engages Newport Coast Securities, Inc. 2Immunomic Therapeutics Engages Newport Coast Securities, Inc. 3
... Ron Van Beek, president and CEO of Van Beek ... for dogs and cats, available exclusively through veterinarians. ... supplement containing both probiotics and prebiotics that work together ... dog,s or cat,s GI tract.  Van Beek Natural Science,s ...
... Pharmaceuticals, Inc. (Nasdaq: AUXL ), a specialty biopharmaceutical ... year 2010 on Thursday, February 10, 2011 before the opening ... a conference call that day at 10:00 a.m. ET to ... year 2010.  The presentation slides to be used during the ...
... Barrow Neurological Institute scientist on the thermoregulatory effects of a ... the cover story in the Feb. 2 issue of the ... an international team led by Andrej Romanovsky, MD, PhD, Director ... a part of St. Joseph,s Hospital and Medical Center. ...
Cached Biology Technology:Van Beek Natural Science Announces New Synacore Digestive Support Product 2Auxilium Pharmaceuticals to Announce Fourth Quarter and Full Year 2010 Results and Conduct Conference Call on Thursday, February 10, 2011 2Auxilium Pharmaceuticals to Announce Fourth Quarter and Full Year 2010 Results and Conduct Conference Call on Thursday, February 10, 2011 3Auxilium Pharmaceuticals to Announce Fourth Quarter and Full Year 2010 Results and Conduct Conference Call on Thursday, February 10, 2011 4Barrow TRPV1 research highlighted in Journal of Neuroscience 2
(Date:7/28/2014)... a mechanism in part of the brain that is key ... both type 1 and type 2 diabetes. The findings are ... the National Academies of Sciences . , "We,ve discovered ... of the hypothalamus known as the ventromedial nucleus sets ... in the blood," said lead author Sabrina Diano, professor in ...
(Date:7/28/2014)... have seen an increase in so-called "nuisance flooding"--which causes ... drains and compromised infrastructure--are on the East Coast, according ... flooding, caused by rising sea levels, has increased on ... since the 1960s. , The report, Sea Level Rise ... also finds Annapolis and Baltimore, Maryland, lead the list ...
(Date:7/28/2014)... the Earth that are high priorities for conservation in ... vulnerable, as it has the lowest fraction of its ... in ,refugia, areas of biological diversity that support ... during times of great environmental change. The refugia that ... Scotland. , The biggest refugia are in the ...
Breaking Biology News(10 mins):Glucose 'control switch' in the brain key to both types of diabetes 2NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 2NOAA: 'Nuisance flooding' an increasing problem as coastal sea levels rise 3Study finds Europe's habitat and wildlife is vulnerable to climate change 2
... 2010 --Canadian biologist Chris Wood was presented with the ... was presented by Dr. Philip Campbell, editor-in-chief of ... annual meeting in Toronto earlier this week. ... Canada, is a professor in the Department of Biology ...
... mildew is a fungus that infects both crop and ornamental ... immense crop loss. Despite decades of intense research, little is ... invade the host,s epidermal cells. A European research group lead ... Zurich, now published a study in Science shedding ...
... a walk knows that children tire more quickly than adults, ... differently from taller people or do they tire faster for ... is fascinated by the effect that body size has on ... resting metabolic rates for different sized animals. He found that ...
Cached Biology News:Nature honors outstanding faculty mentor 2Fertility or powdery mildew resistance? 2Fertility or powdery mildew resistance? 3New equation calculates cost of walking for first time 2New equation calculates cost of walking for first time 3
... is a diluent that is designed for use ... are paired with a mouse monoclonal coating antibody. ... and mouse proteins to prevent non-specific binding between ... This buffer may be used to ...
... in solution or in a gel piece, we ... will be digested to produce a mixture of ... are determined by MALDI-TOF, and the amino acid ... MALDI-TOF will be determined by MALDI-TOF/TOF. The masses ...
OmniSlide Heated Wash Module. 2 independent chambers with precise temperature control from ambient of 5C to 70C. Each chamber holds 1 slide rack (20 slides). Includes 2 x Wash Sleeves, 1 x Slide R...
For cleavage of 6xHis tags from proteins containing a Factor Xa Protease recognition site Efficient 6xHis tag cleavage (greater than 90%), ...
Biology Products: