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Streamlined Transfection Protocol
siRNA transfection is traditionally a two-day procedure,
making optimization a relatively slow process. siPORT NeoFX Transfection
Agent was developed to refine siRNA transfection protocols. siPORT NeoFX
lipid-based formulation can be used to efficiently transfect adherent
cells just after trypsinization--without increased cytotoxicity. Just
add siPORT NeoFX to your diluted siRNA, incubate to form transfection
complexes, add the complexes to the culture wells, and overlay with cells
(Figure 1). This new streamlined protocol, named "neofection," will save
researchers a full day of valuable time when compared to traditional pre-plated
transfection procedures. The transfection complexes are active and stable
even in the presence of serum, so there is no need to remove or replace
media following transfection. From start to finish, successful gene silencing
experiments can be completed i
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