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Sex Steroid Regulation of Vasopressin Levels Secreted by hNT Neurons*

demonstrate that hNT neurons synthesize the neuropeptide vasopressin. As previously demonstrated with animal models,2,5 hNT neuronal vasopressin synthesis responds to testosterone treatment. Incorporation of [35S]methionine indicates that hNT neurons appear to increase total neuronal protein synthesis in response to dihydrotestosterone.

Conclusions

Stratagenes hNT Neurons provide a viable model that may resemble the human aging brain more closely than previous animal models. Our results show that these neurons respond to various sex steroids and to varying concentrations of sex steroids. hNT neurons provide opportunities for research in the areas of steroid-responsive neuropeptides and age-related neurodegeneration.

Acknowledgments

The authors would like to thank the American Osteopathic Association and Glaxo-Wellcome for fellowship support.

REFERENCES

  1. Gur, R.C., et al. (1991) Proc. Natl. Acad. Sci. USA. 88: 2845-2849.

  2. Brenner, W.J., Vitiello, M.V., and Prinz, P.N. (1983) J. Clin. Endocrinol. Metab. 56: 1278-1287.

  3. Ravid, R., et al. (1987) Gerontology 33: 87-98.

  4. Dantzer, R., et al. (1988) Brain Res. 457: 143-147.

  5. Dorsa, D.M., and Bottemiller, L.A. (1982) Brain Res. 242: 3237-3242.

  6. Fliers, E., De Vries, G.J., and Swaab, D.F. (1985) Brain Res. 348: 1-8.

  7. Dobie, D.J., et al. (1992) Brain Res. 583: 247-252.

  8. Miller, M.A., Urban, J.H., and Dorsa, D.M. (1989) Endocrinology 125: 2335-2340.

  9. Devries, G.J., Duetz, W., and Buijs, R.M. (1984) Dev. Brain Res. 298: 141-145.

  10. Paganini-Hill, A.
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